公开(公告)号：DE69821019T2

公开(公告)日：2004-10-28

申请号：DE69821019

申请日：1998-10-27

Applicant: HOWARD UNIVERSITY WASHINGTON

Inventor： SCOTT R ,  LAWS L ,  ROBERTS R ,  NICHOLSON M

IPC: C07D279/20 ,  A61K31/5415 ,  A61P25/08 ,  A61P25/12

Abstract: Phenothiazines of the formula: where R1 is H or -COOR, where R is selected from the group consisting of branched or unbranched alkyl groups containing from 1 to 4 carbon atoms, and where X is selected from H, branched or unbranched alkyl groups containing from 1 to 4 carbons, and halogen, and pharmaceutically acceptable salts thereof. Particularly preferred phenothiazines are those wherein X is hydrogen, chloro, bromo or methyl, R1 is COOR, and R is methyl, ethyl or t-butyl.

公开(公告)号：DE69821019D1

公开(公告)日：2004-02-12

申请号：DE69821019

申请日：1998-10-27

Applicant: HOWARD UNIVERSITY WASHINGTON

Inventor： SCOTT R ,  LAWS L ,  ROBERTS R ,  NICHOLSON M

IPC: C07D279/20 ,  A61K31/5415 ,  A61P25/08 ,  A61P25/12

Abstract: Phenothiazines of the formula: where R1 is H or -COOR, where R is selected from the group consisting of branched or unbranched alkyl groups containing from 1 to 4 carbon atoms, and where X is selected from H, branched or unbranched alkyl groups containing from 1 to 4 carbons, and halogen, and pharmaceutically acceptable salts thereof. Particularly preferred phenothiazines are those wherein X is hydrogen, chloro, bromo or methyl, R1 is COOR, and R is methyl, ethyl or t-butyl.