公开(公告)号：CA2364686C

公开(公告)日：2007-04-24

申请号：CA2364686

申请日：2000-02-09

Applicant: ID LELYSTAD INST DIERHOUDERIJ

Inventor： LANGEVELD JOHANNES PIETER MARI ,  SMITS MARINUS ADRIANUS ,  BOSSERS ALEXANDER ,  SCHREUDER BRAM EDWARD CORNELIS ,  VAN KEULEN LUCIEN JOHANNES MAT ,  JACOBS JORG GUNTHER ,  GARSSEN GERRIT JAN

IPC: G01N33/68 ,  C12Q1/37 ,  G01N33/53

Abstract: The invention is related to diagnostic methods for detecting transmissible spongiform encephalopathies (TSEs) such as BSE and scrapie and related disea se in humans. The invention provides use of guanidine thiocyanate (gdnSCN) or a functional equivalent thereof for treating at least one sample derived from a mammal, including humans for reducing the risk of scoring a false-positive test result in testing said sample for the presence or absence of aberrant prion protein.