公开(公告)号：US12241900B2

公开(公告)日：2025-03-04

申请号：US18432995

申请日：2024-02-05

Applicant: IDEXX LABORATORIES, INC.

Inventor： Mahalakshimi Yerramilli ,  Michael Randolph Atkinson ,  Murthy V. S. N. Yerramilli

IPC: G01N33/68 ,  G01N33/53 ,  G01N33/92

Abstract: This invention provides reagents and methods for diagnosing renal disease. Differential levels of inosine metabolite, and proteins: apolipoprotein C-I, apolipoprotein C-II, fibrinogen alpha chain, or fibrinogen A-alpha chain, kininogen, Inter-Alpha Inhibitor H4 (ITIH4), keratin Type I cytoskeletol 10 cystatin A, cystatin B and other polypeptides and fragments thereof provide biomarkers of renal disease and are described herein.

公开(公告)号：US11933792B2

公开(公告)日：2024-03-19

申请号：US17815765

申请日：2022-07-28

Applicant: IDEXX LABORATORIES, INC.

Inventor： Mahalakshimi Yerramilli ,  Michael Randolph Atkinson ,  Murthy V. S. N. Yerramilli

IPC: G01N33/68 ,  G01N33/53 ,  G01N33/92

CPC classification number: G01N33/6893 ,  G01N33/5308 ,  G01N33/92 ,  G01N2800/347 ,  G01N2800/60

Abstract: This invention provides reagents and methods for diagnosing renal disease. Differential levels of inosine metabolite, and proteins: apolipoprotein C-I, apolipoprotein C-II, fibrinogen alpha chain, or fibrinogen A-alpha chain, kininogen, Inter-Alpha Inhibitor H4 (ITIH4), keratin Type I cytoskeletol 10 cystatin A, cystatin B and other polypeptides and fragments thereof provide biomarkers of renal disease and are described herein.