公开(公告)号：US20240068947A1

公开(公告)日：2024-02-29

申请号：US18269557

申请日：2021-12-22

Applicant: INDIAN INSTITUTE OF SCIENCE

Inventor： Siva UMAPATHY ,  Sanchita SIL ,  Dipak KUMBHAR ,  Srividya KUMAR

IPC: G01N21/65

CPC classification number: G01N21/65 ,  G01N2201/06113 ,  G01N2201/0631

Abstract: The invention provides a method for homogenized coherent excitation of a sample for determining molecular structure. The method includes selecting a monochromatic coherent light, homogenizing the monochromatic coherent light; irradiating the sample with the homogenized monochromatic light; collecting the Raman scattered light to obtain a profile and analyzing the profile to obtain chemical specific signature of the sample. The invention also provides a method for obtaining two dimensional imaging of a sample using irradiation of large sample area by homogenized monochromatic light without compromise in spatial resolution. A system for homogenized coherent excitation of a sample for determining molecular structure is also provided.

公开(公告)号：US20180372643A1

公开(公告)日：2018-12-27

申请号：US15781150

申请日：2016-01-27

Applicant: INDIAN INSTITUTE OF SCIENCE

Inventor： Siva UMAPATHY ,  Deepak Kumar SAINI ,  Srividya KUMAR

IPC: G01N21/65 ,  G01N1/34

Abstract: The invention provides a method for rapid detection of a specific bacterial species. The method includes preparing a sample, irradiating the prepared sample with an electromagnetic radiation of specific wavelength, capturing the electromagnetic radiation scattered by the sample to obtain a Raman spectra and analyzing the Raman spectra to obtain a unique biochemical signature. The unique biochemical signature identifies a single bacterium within the sample. The method also provides for rapid detection of a group of bacterial species within the sample. The method takes about 1 minute to about 1 hour for the detection of specific bacterial species.