公开(公告)号：CA966144A

公开(公告)日：1975-04-15

申请号：CA132563

申请日：1972-01-17

Applicant: INDIANA UNIVERSITY FOUNDATION

Inventor： KATZ SIMON

IPC: A61K8/69 ,  A61K33/16 ,  A61K33/24 ,  A61Q11/00 ,  C01G19/00 ,  C07C55/06 ,  C07C55/07 ,  C07C69/36

Abstract: A new genus of compositions of matter, namely, difluoroxalatostannate(II) complexes has been discovered. These compounds when incorporated into oral compositions for dental caries prophylaxis (e.g., as a constituent of a dentifrice, prophylaxis paste, or mouthwash), have demonstrated substantial utility as an anticariogenic agent.

公开(公告)号：CA1029308A

公开(公告)日：1978-04-11

申请号：CA196228

申请日：1974-03-28

Applicant: INDIANA UNIVERSITY FOUNDATION

Inventor： KATZ SIMON

IPC: A61K8/00 ,  A61K8/21 ,  A61K8/24 ,  A61K8/362 ,  A61K8/55 ,  A61K8/69 ,  A61Q5/12 ,  A61Q11/00

Abstract: New compositions effective in inhibiting the formation of dental plaque comprise an antibacterial agent in combination with an enamel conditioning agent to facilitate incorporation of the antibacterial agent into the dental enamel. A new method of inhibiting the formation of dental plaque comprises the step of applying such a composition to the oral hard tissues.

公开(公告)号：DE2202142A1

公开(公告)日：1972-07-27

申请号：DE2202142

申请日：1972-01-18

Applicant: INDIANA UNIVERSITY FOUNDATION

Inventor： KATZ SIMON

IPC: A61K8/69 ,  A61K33/16 ,  A61K33/24 ,  A61Q11/00 ,  C01G19/00 ,  C07C55/06 ,  C07C55/07 ,  C07C69/36 ,  A61K7/16

Abstract: A new genus of compositions of matter, namely, difluoroxalatostannate(II) complexes has been discovered. These compounds when incorporated into oral compositions for dental caries prophylaxis (e.g., as a constituent of a dentifrice, prophylaxis paste, or mouthwash), have demonstrated substantial utility as an anticariogenic agent.

公开(公告)号：US3678153A

公开(公告)日：1972-07-18

申请号：US3678153D

申请日：1971-01-20

Applicant: INDIANA UNIVERSITY FOUNDATION

Inventor： KATZ SIMON

IPC: A61K8/69 ,  A61K33/16 ,  A61K33/24 ,  A61Q11/00 ,  C01G19/00 ,  C07C55/06 ,  C07C55/07 ,  C07C69/36 ,  A61K7/16

CPC classification number: C07C55/07 ,  A61K8/69 ,  A61Q11/00 ,  C01G19/00

Abstract: A new genus of compositions of matter, namely, difluoroxalatostannate(II) complexes has been discovered. These compounds when incorporated into oral compositions for dental caries prophylaxis (e.g., as a constituent of a dentifrice, prophylaxis paste, or mouthwash), have demonstrated substantial utility as an anticariogenic agent.

Abstract translation: 已经发现了一种新的物质组成，即二氟草酸盐（II）配合物。 这些化合物当掺入用于龋齿预防的口腔组合物中（例如，作为洁齿剂，预防膏或漱口剂的组分）已经证明作为抗龋剂的实用性。

公开(公告)号：US3897548A

公开(公告)日：1975-07-29

申请号：US34927473

申请日：1973-04-09

Applicant: INDIANA UNIVERSITY FOUNDATION

Inventor： KATZ SIMON

IPC: A61K8/00 ,  A61K8/21 ,  A61K8/24 ,  A61K8/362 ,  A61K8/55 ,  A61K8/69 ,  A61Q5/12 ,  A61Q11/00 ,  A61K7/22

CPC classification number: A61K8/21 ,  A61K8/24 ,  A61K8/362 ,  A61K8/55 ,  A61K8/69 ,  A61Q11/00

Abstract: New compositions effective in inhibiting the formation of dental plaque comprise an antibacterial agent in combination with an enamel conditioning agent to facilitate incorporation of the antibacterial agent into the dental enamel. A new method of inhibiting the formation of dental plaque comprises the step of applying such a composition to the oral hard tissues.

Abstract translation: 有效抑制牙斑形成的新组合物包括与搪瓷调理剂组合的抗菌剂，以促进抗菌剂掺入牙釉质中。 抑制牙斑形成的新方法包括将这样的组合物施用于口腔硬组织的步骤。