-
1.发明申请METHOD OF SELECTIVELY RELEASING NITROGEN MONOXIDE USING MESOPOROUS CORE-SHELL NANOPARTICLE AND CALCIUM PHOSPHATE 审中-公开使用多孔核壳纳米颗粒和磷酸钙选择性释放一氧化氮的方法
公开(公告)号：WO2017051989A1
公开(公告)日：2017-03-30
申请号：PCT/KR2015/013351
申请日：2015-12-08
Inventor： KIM, Won Jong , KIM, Jihoon , CHOI, Hyung Woo
CPC classification number: A61K41/0028 , A61K9/5115
Abstract: Provided is a method of controlling release of nitrogen monoxide, and more particularly, a method of selectively releasing nitrogen monoxide using mesoporous silica nanoparticles including a material capable of emitting protons by light irradiation and calcium phosphate. The technique according to the present invention to control release of nitrogen monoxide by light irradiation may stably deliver nitrogen monoxide to a desired part, and induces release of nitrogen monoxide only when irradiated with light, thereby maximizing a therapeutic effect.
Abstract translation: 本发明提供一种控制一氧化氮释放的方法，更具体地说，涉及使用包括能够通过光照射发射质子的材料和磷酸钙的介孔二氧化硅纳米粒子选择性地释放一氧化氮的方法。 根据本发明的用于通过光照射来控制一氧化氮释放的技术可以将一氧化氮稳定地输送到期望的部分，并且仅在用光照射时才诱导一氧化氮的释放，从而最大化治疗效果。
-
Patent Agency Ranking2.发明申请
公开(公告)号：WO2018128420A1
公开(公告)日：2018-07-12
申请号：PCT/KR2018/000190
申请日：2018-01-04
Inventor： KIM, Jihoon , KIM, Bumman , MOON, Kyunghoon , LEE, Seokwon , JEONG, Daechul , PARK, Byungjoon , SON, Juho
Abstract: The method and system for converging a 5th-generation (5G) communication system for supporting higher data rates beyond a 4th-generation (4G) system with a technology for internet of things (IoT) are provided. The method includes intelligent services based on the 5G communication technology and the IoT-related technology, such as smart home, smart building, smart city, smart car, connected car, health care, digital education, smart retail, security and safety services. The system includes a power amplification device capable of minimizing the effect of envelope impedance. The power amplification device may be incorporated in a terminal and a base station.
-
公开(公告)号：WO2012046994A3
公开(公告)日：2012-04-12
申请号：PCT/KR2011/007316
申请日：2011-10-04
Applicant: POSTECH ACADEMY-INDUSTRY FOUNDATION , KIM, Won Jong , LEE, Yanggy , PARK, Kwideok , KIM, Jihoon , HAN, Dong Keun
Inventor： KIM, Won Jong , LEE, Yanggy , PARK, Kwideok , KIM, Jihoon , HAN, Dong Keun
Abstract: A donor capable of controlled release of nitric monoxide and a prosthetic implant whose surface is coated with this donor are disclosed. The donor comprises a main chain of an organic polymer and a side chain that is covalently linked to the main chain and has a diazeniumdiolate functional group. The donor for controlled release of nitric monoxide exists in a fluid state such as liquid at room temperature and undergoes a sol-to-gel phase transition at a physiological pH as the temperature increases above the critical temperature. The critical temperature of the phase transition is in the range of 25 to 35°C, and the gel is a hydrogel without chemical cross-links.
-
4.发明申请
公开(公告)号：WO2012046994A2
公开(公告)日：2012-04-12
申请号：PCT/KR2011/007316
申请日：2011-10-04
Applicant: POSTECH ACADEMY-INDUSTRY FOUNDATION , KIM, Won Jong , LEE, Yanggy , PARK, Kwideok , KIM, Jihoon , HAN, Dong Keun
Inventor： KIM, Won Jong , LEE, Yanggy , PARK, Kwideok , KIM, Jihoon , HAN, Dong Keun
CPC classification number: C08G73/024 , A61K47/34 , A61L27/34 , A61L27/54 , A61L2300/114 , C08G63/6852 , C08G73/0206 , C08L71/02
Abstract: A donor capable of controlled release of nitric monoxide and a prosthetic implant whose surface is coated with this donor are disclosed. The donor comprises a main chain of an organic polymer and a side chain that is covalently linked to the main chain and has a diazeniumdiolate functional group. The donor for controlled release of nitric monoxide exists in a fluid state such as liquid at room temperature and undergoes a sol-to-gel phase transition at a physiological pH as the temperature increases above the critical temperature. The critical temperature of the phase transition is in the range of 25 to 35°C, and the gel is a hydrogel without chemical cross-links.
Abstract translation: 公开了一种能够控制释放一氧化氮的供体和其表面涂覆有该供体的假体植入物。 供体包含有机聚合物的主链和与主链共价连接并具有二醇二氮烯鎓官能团的侧链。 控制释放一氧化氮的供体在室温下以液体状态如液体存在，并且随着温度升高至临界温度以上而在生理pH下发生溶胶 - 凝胶相变。 相转变的临界温度在25至35℃的范围内，并且凝胶是没有化学交联的水凝胶。
-
公开(公告)号：WO2012046994A9
公开(公告)日：2012-04-12
申请号：PCT/KR2011/007316
申请日：2011-10-04
Applicant: POSTECH ACADEMY-INDUSTRY FOUNDATION , KIM, Won Jong , LEE, Yanggy , PARK, Kwideok , KIM, Jihoon , HAN, Dong Keun
Inventor： KIM, Won Jong , LEE, Yanggy , PARK, Kwideok , KIM, Jihoon , HAN, Dong Keun
Abstract: A donor capable of controlled release of nitric monoxide and a prosthetic implant whose surface is coated with this donor are disclosed. The donor comprises a main chain of an organic polymer and a side chain that is covalently linked to the main chain and has a diazeniumdiolate functional group. The donor for controlled release of nitric monoxide exists in a fluid state such as liquid at room temperature and undergoes a sol-to-gel phase transition at a physiological pH as the temperature increases above the critical temperature. The critical temperature of the phase transition is in the range of 25 to 35°C, and the gel is a hydrogel without chemical cross-links.
-
6.发明公开
公开(公告)号：EP3529894A1
公开(公告)日：2019-08-28
申请号：EP18736317.1
申请日：2018-01-04
Inventor： KIM, Jihoon , KIM, Bumman , MOON, Kyunghoon , LEE, Seokwon , JEONG, Daechul , PARK, Byungjoon , SON, Juho
-
-
-
-
-
Search Results
6
records
(took 0.034 seconds)
