公开(公告)号：US20210077521A1

公开(公告)日：2021-03-18

申请号：US16621442

申请日：2018-06-14

Applicant: INSTITUTE FOR BASIC SCIENCE ,  POSTECH ACADEMY-INDUSTRY FOUNDATION

Inventor： Sin-Hyeog IM ,  Ravi VERMA ,  Changhon LEE

IPC: A61K31/716 ,  C12N5/0783 ,  A61K35/745

Abstract: The present invention relates to a Bifidobacterium bifidum inducing regulatory T cells (Treg), a polysaccharide derived from Bifidobacterium bifidum, and a probiotic strain producing a polysaccharide and, more particularly, a polysaccharide containing β-1-6-glucan as an effective ingredient, a probiotic strain producing β-1-6-glucan, a food comprising the polysaccharide or strain as an effective ingredient for alleviation of immune disease or inflammatory disease, a therapeutic agent comprising the polysaccharide or strain as an effective ingredient for alleviation of immune disease or inflammatory disease, a method for preparing induced regulatory T cells (iTreg) by treatment with the polysaccharide or strain, and a cell therapy product for prevention or treatment of immune disease or inflammatory disease, comprising the induced regulatory T cells prepared by the method.