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公开(公告)号:US11660312B2
公开(公告)日:2023-05-30
申请号:US16621442
申请日:2018-06-14
Inventor: Sin-Hyeog Im , Ravi Verma , Changhon Lee
IPC: A61K31/716 , A61K35/745 , C12N1/20 , A61P37/02 , A61P37/08 , A61P29/00 , C08B37/00 , C08L5/00
CPC classification number: A61K31/716 , A61K35/745 , A61P29/00 , A61P37/02 , A61P37/08 , C08B37/0024 , C08L5/00 , C12N1/205 , A23V2200/324 , A23Y2300/25 , Y10S424/831
Abstract: The present invention relates to a Bifidobacterium bifidum inducing regulatory T cells (Treg), a polysaccharide derived from Bifidobacterium bifidum, and a probiotic strain producing a polysaccharide and, more particularly, a polysaccharide containing β-1-6-glucan as an effective ingredient, a probiotic strain producing β-1-6-glucan, a food comprising the polysaccharide or strain as an effective ingredient for alleviation of immune disease or inflammatory disease, a therapeutic agent comprising the polysaccharide or strain as an effective ingredient for alleviation of immune disease or inflammatory disease, a method for preparing induced regulatory T cells (iTreg) by treatment with the polysaccharide or strain, and a cell therapy product for prevention or treatment of immune disease or inflammatory disease, comprising the induced regulatory T cells prepared by the method.