公开(公告)号：WO1994012089A1

公开(公告)日：1994-06-09

申请号：PCT/US1993010882

申请日：1993-11-12

Applicant: INTELLIWIRE, INC.

Inventor： INTELLIWIRE, INC. ,  IMRAN, Mir, A.

IPC: A61B01/00

CPC classification number: A61M25/0158 ,  A61M25/0054 ,  C08L2201/12

Abstract: A device comprising a flexible elongate member having proximal (72) and distal extremities (41). A flexible coil spring is provided having proximal and distal extremities. The proximal extremity of the coil spring is secured to the distal extremity of the flexible elongate member. A shape memory alloy element (46) is disposed within and extends substantially longitudinally of the coil spring (36). The shape memory alloy element has a memory which makes it attempt to assume a straight shape when an electrical current is passed through and heats the same. The shape memory alloy element (46) also has a stiffness which increases with the temperature of the element. An electrical current supply (67) is provided for supplying an electrical current to the shape memory alloy element for changing the stiffness of the shape memory alloy element to thereby stiffen the distal extremity of the flexible elongate member.

Abstract translation: 一种包括具有近端（72）和远端（41）的柔性细长构件的装置。 提供了具有近端和远端的柔性螺旋弹簧。 螺旋弹簧的近端被固定到柔性细长构件的远端。 形状记忆合金元件（46）设置在螺旋弹簧（36）的大致纵向上并且基本上沿其延伸。 形状记忆合金元件具有当电流通过并使其加热时尝试呈现直线形状的存储器。 形状记忆合金元件（46）还具有随着元件的温度而增加的刚度。 提供电流源（67），用于向形状记忆合金元件提供电流，以改变形状记忆合金元件的刚度，从而加强柔性细长构件的远端。

公开(公告)号：WO1996013297A1

公开(公告)日：1996-05-09

申请号：PCT/US1995013464

申请日：1995-10-10

Applicant: INTELLIWIRE, INC.

Inventor： INTELLIWIRE, INC. ,  IMRAN, Mir, A. ,  GANDHI, Deepak, R. ,  BROOKS, Dennis, L.

IPC: A61M29/00

CPC classification number: A61M25/0158 ,  A61M25/0097 ,  A61M25/104 ,  A61M2025/0186 ,  A61M2025/1079 ,  A61M2025/1093

Abstract: A low profile balloon-on-a-wire catheter (11) comprising a flexible elongate tubular member (12) having proximal and distal extremities (13, 14). A balloon inflation/deflation lumen extends from the proximal extremity to the distal extremity. An inflatable balloon (26) is carried by the distal extremity of the flexible elongate tubular member (12). The flexible elongate tubular member (12) carries means which establishes communication between the lumen and the interior of the inflatable balloon (31). A removable inflation device (51) is removably secured to the proximal extremity of the flexible elongate tubular member (12) for supplying an inflation fluid to the lumen for inflating and deflating the balloon (26). The removable inflation device (51) forms a high pressure seal with the proximal extremity of the flexible elongate tubular member (12). The removable inflation device (51) is free of obstructions so that another balloon catheter can be advanced over the proximal extremity of the flexible elongate tubular member (12) which serves as stand-alone guide wire. The distal extremity of the catheter is formed so that it is mechanically shapable or can be electrically deflectable to facilitate steering of the distal extremity.

Abstract translation: 包括具有近端和远端（13,14）的柔性细长管状构件（12）的薄型气球在线导管（11）。 气球充气/通气腔从近端延伸到远端。 可膨胀气囊（26）由柔性细长管状构件（12）的远端承载。 柔性细长管状构件（12）承载建立管腔和可膨胀气囊（31）内部之间的连通的装置。 可移除的充气装置（51）可移除地固定到柔性细长管状构件（12）的近端，用于向腔内供应充气流体，以使球囊（26）膨胀和放气。 可移除的充气装置（51）与柔性细长管状构件（12）的近端形成高压密封。 可移除的充气装置（51）没有障碍物，使得另一气囊导管可以在用作独立导丝的柔性细长管状构件（12）的近端延伸。 导管的远端被形成为使得其可机械地成形或可以电可偏转以便于远端的转向。

公开(公告)号：WO1995006494A1

公开(公告)日：1995-03-09

申请号：PCT/US1994009743

申请日：1994-08-30

Applicant: INTELLIWIRE, INC.

Inventor： INTELLIWIRE, INC. ,  IMRAN, Mir

IPC: A61M37/00

CPC classification number: A61M25/0158 ,  A61M25/0054 ,  C08L2201/12

Abstract: This invention is a flexible elongate device comprising a flexible elongate member with proximal (13) and distal (56) extremities. A shape memory element (31) is disposed in the flexible elongate member and is capable of assuming martensitic and austenitic states and has first and second portions. A layer of conductive material (36) is formed on at least one of said portions. The layer has a conductivity greater than that of the shape memory element. Electrical current is supplied to the shape memory element. The conductive (36) layer serves to conduct current and shunts current flow around that portion of the shape memory element (31) having the layer of conductive material thereon.

Abstract translation: 本发明是一种柔性细长装置，其包括具有近端（13）和远端（56）末端的柔性细长构件。 形状记忆元件（31）设置在柔性细长构件中并且能够呈现马氏体和奥氏体状态并具有第一和第二部分。 一层导电材料（36）形成在至少一个所述部分上。 该层的导电率大于形状记忆元件的导电率。 电流被提供给形状记忆元件。 导电层（36）用于传导电流并且绕其上具有导电材料层的形状记忆元件（31）的该部分周围的电流流动。

公开(公告)号：WO1995006432A1

公开(公告)日：1995-03-09

申请号：PCT/US1994009742

申请日：1994-08-30

Applicant: INTELLIWIRE, INC.

Inventor： INTELLIWIRE, INC. ,  IMRAN, Mir

IPC: A61B05/00

CPC classification number: A61M25/0158 ,  A61B1/0053 ,  A61M2025/0161

Abstract: This invention is an elongate device (11) for insertion into a body cavity comprising an elongate tubular member (12) having proximal and distal extremities. First and second elongate temperature activated shape memory elements (46) are carried by and disposed within at least a portion of the elongate tubular member (12).

Abstract translation: 本发明是用于插入体腔的细长装置（11），其包括具有近端和远端的细长管状构件（12）。 第一和第二细长温度激活形状记忆元件（46）由细长管状构件（12）的至少一部分承载并设置在细长管状构件（12）的至少一部分内。

公开(公告)号：WO1997016113A1

公开(公告)日：1997-05-09

申请号：PCT/US1996014701

申请日：1996-09-13

Applicant: INTELLIWIRE, INC.

Inventor： INTELLIWIRE, INC. ,  QUIACHON, Dignah, B. ,  BROOKS, Dennis, L. ,  GANDHI, Deepak, R. ,  IMRAN, Mir, A.

IPC: A61B05/00

CPC classification number: A61M25/0905

Abstract: This invention is a guide wire assembly for use in a vascular system of a patient in a medical procedure comprising a guide wire adapted to extend into a patient's vascular system. The guide wire has a proximal extremity (12) extending out of the patient. A guide wire extension (13) is provided which has a distal extremity. A connector (36) is provided for forming a repetitive connection between the proximal extremity of the guide wire (12) and the distal extremity of the guide wire extension. The connector is formed of a male (31) and female (16) parts. At least one of the male and female parts is formed of a super-elastic memory material.

Abstract translation: 本发明是用于医疗过程中患者血管系统的导丝组件，其包括适于延伸到患者血管系统中的导丝。 引导线具有从病人伸出的近端（12）。 提供具有远端的导丝延伸部（13）。 提供连接器（36），用于在导丝（12）的近端与导丝延伸部的远端之间形成重复连接。 连接器由阳（31）和阴（16）部分形成。 男性和女性部分中的至少一个由超弹性记忆材料形成。

公开(公告)号：WO1996013206A1

公开(公告)日：1996-05-09

申请号：PCT/US1995013732

申请日：1995-10-23

Applicant: INTELLIWIRE, INC.

Inventor： INTELLIWIRE, INC. ,  IMRAN, Mir, A. ,  GANDHI, Deepak, R. ,  BOURANG, Henry ,  QUIACHON, Dignah, B. ,  CHOW, Andrew, Y.

IPC: A61B05/00

CPC classification number: A61M25/0144 ,  A61M25/0054 ,  A61M25/0158 ,  A61M25/09 ,  A61M2025/0063 ,  A61M2025/0915 ,  H04L7/0008

Abstract: The present invention is a guidewire (16) for use in a medical procedure, and for use with the power supply (18) comprising a flexible elongate member (22) having proximal and distal extremities, and having a bore (26) extending from the proximal extremity to the distal extremity. A core wire (28) extends through the bore (26) of the flexible elongate tubular member (22). A coil assembly (61) is mounted on the distal extremity of the flexible elongate member (22) and ends in a rounded tip (48). An actuator member (64) has at least a portion thereof disposed in the coil assembly (61).

Abstract translation: 本发明是用于医疗过程的导丝（16），并且与电源（18）一起使用，该电源（18）包括具有近端和远端的柔性细长构件（22），并且具有从该 近端到远端。 芯线（28）延伸穿过柔性细长管状构件（22）的孔（26）。 线圈组件（61）安装在柔性细长构件（22）的远端上并且终止于圆形尖端（48）。 致动器构件（64）的至少一部分设置在线圈组件（61）中。

公开(公告)号：WO1994026323A2

公开(公告)日：1994-11-24

申请号：PCT/US1994004697

申请日：1994-04-28

Applicant: INTELLIWIRE, INC.

Inventor： INTELLIWIRE, INC. ,  IMRAN, Mir, A. ,  ZADNO-AZIZI, Gholam-Reza ,  POMERANZ, Mark, L.

IPC: A61M00/00

CPC classification number: A61M25/0158 ,  A61M25/09033 ,  A61M2025/0161

Abstract: Device comprising an elongate tubular member having proximal and distal extremities and having a section with a plurality of lumens extending from the proximal extremity to the section. At least two conductive elements are disposed in the lumens in said section of the elongate tubular member. The conductive elements are formed of a conductive metal alloy having a recoverable strain in excess of 1 % and exhibiting a martensitic phase transformation. Electrical current is supplied to the at least one conductive element. The section has at least one portion. A current conductor is carried by said at least one conductive element for shunting current flow around the at least one portion of said at least one conductive element.

Abstract translation: 装置包括具有近端和远端的细长管状构件，并具有具有从近端延伸至所述区段的多个内腔的区段。 至少两个导电元件设置在细长管状构件的所述部分中的内腔中。 导电元件由具有超过1％的可恢复应变并显示马氏体相变的导电金属合金形成。 电流被提供给至少一个导电元件。 该部分至少有一部分。 电流导体由所述至少一个导电元件承载，用于分流围绕所述至少一个导电元件的至少一部分的电流。

公开(公告)号：WO1997004829A1

公开(公告)日：1997-02-13

申请号：PCT/US1996009481

申请日：1996-06-05

Applicant: INTELLIWIRE, INC.

Inventor： INTELLIWIRE, INC. ,  IMRAN, Mir, A. ,  GANDHI, Deepak, R. ,  HEGDE, Anant, V.

IPC: A61M29/00

CPC classification number: A61M25/104 ,  A61M25/1002 ,  A61M25/1011 ,  A61M2025/1013

Abstract: This invention is a low profile catheter (21) comprising a flexible elongate tubular member (22) having proximal and distal extremities (23, 24), and having a guide wire lumen (26), and at least one balloon inflation lumen (27) extending from the proximal extremity to the distal extremity (24), said at least one balloon inflation lumen being offset eccentrically with respect to said guide wire lumen (26) having at least one inflatable balloon (31) formed thereon and having an interior in communication with said at least one balloon inflation lumen (27); said guide wire lumen (26) extending through said at least one inflatable balloon (30) and being offset eccentrically with respect to said at least one inflatable balloon (31).

Abstract translation: 本发明是一种薄型导管（21），其包括具有近端和远端（23,24）的柔性细长管状构件（22），并具有导丝管腔（26）和至少一个球囊充气腔（27） 从所述近端末端延伸到所述远端（24），所述至少一个球囊充气腔相对于所述导丝管腔（26）偏心地偏移，所述导丝管腔具有形成在其上的至少一个可充气气囊（31） 与所述至少一个球囊充气腔（27）相连; 所述导丝管腔（26）延伸穿过所述至少一个可充气气囊（30）并且相对于所述至少一个可充气气囊（31）偏心偏移。

公开(公告)号：WO1996029001A1

公开(公告)日：1996-09-26

申请号：PCT/US1996003269

申请日：1996-03-15

Applicant: INTELLIWIRE, INC.

Inventor： INTELLIWIRE, INC. ,  IMRAN, Mir, A. ,  GANDHI, Deepak, R. ,  BROOKS, Dennis, L.

IPC: A61B05/00

CPC classification number: A61M25/01 ,  A61M25/0905

Abstract: This invention has a guidewire extension capability for use in a medical procedure having a guidewire (12) and a guidewire extension (13). The guidewire comprises a flexible elongate cylindrical member (16) having proximal and distal extremities. A portion of the distal extremity is formed of a material having high torque ability and high push ability. The guidewire extension comprises a flexible elongate cylindrical member formed of a shape memory material. A major portion of the flexible elongate cylindrical member of the guidewire extension has a shape memory in the form of a coil so that when it is free it will assume a shape memory coil. A junction (14) is formed between the proximal extremity of the guidewire (17) and the distal extremity of the guidewire extension (33) to the guidewire.

Abstract translation: 本发明具有用于具有导丝（12）和导丝延伸部（13）的医疗过程中的导丝延伸能力。 导丝包括具有近端和远端的柔性细长圆柱形构件（16）。 远端的一部分由具有高转矩能力和高推力能力的材料形成。 导丝延伸部包括由形状记忆材料形成的柔性细长圆筒形构件。 导丝延伸件的柔性细长圆柱形构件的主要部分具有线圈形式的形状记忆，使得当其自由时，其将呈现形状记忆线圈。 在导丝（17）的近端和引导线延伸部（33）的远端之间形成有导线（14）。

公开(公告)号：WO1996013298A1

公开(公告)日：1996-05-09

申请号：PCT/US1995013812

申请日：1995-10-25

Applicant: INTELLIWIRE, INC.

Inventor： INTELLIWIRE, INC. ,  IMRAN, Mir, A. ,  GANDHI, Deepak, R.

IPC: A61M29/00

CPC classification number: A61M25/1011 ,  A61M25/104 ,  A61M2025/0183 ,  A61M2025/1013

Abstract: An angioplasty catheter (11) comprising a flexible elongate tubular member (12) having proximal and distal extremities (13 and 14). A lumen (16) therein extends from the proximal extremity (13) to the distal extremity (14). First and second balloons (21 and 22) are carried by said distal extremity (14) and are coaxially disposed with respect to each other on the distal extremity (14) of the flexible elongate tubular member (12). Means (46) are carried by the flexible elongate tubular member (12) for inflating the first and second balloons (21 and 22) one at a time independent of each other.

Abstract translation: 包括具有近端和远端（13和14）的柔性细长管状构件（12）的血管成形术导管（11）。 其中的内腔（16）从近端（13）延伸到远端（14）。 第一和第二气球（21和22）由所述远端（14）承载并且在柔性细长管状构件（12）的远端（14）上相对于彼此同轴设置。 装置（46）由柔性细长管状构件（12）承载，用于一次一个地彼此独立地膨胀第一和第二气囊（21和22）。