公开(公告)号：US10087201B2

公开(公告)日：2018-10-02

申请号：US14404030

申请日：2013-05-24

Applicant: INVISTA NORTH AMERICA S.A R.L.

Inventor： Sudhir Aki ,  Thomas E. Vos

IPC: C07F9/145 ,  C07F9/6574 ,  B01J31/18

Abstract: A process of hydrolyzing a monodentate, bidentate or tridentate phosphorus-based phosphite ester ligand or ligand blend for a transition metal catalyst comprising contacting the ligand or ligand blend with a hydrolysis catalyst of the formula (R11X11)nP(OH)3-n where n is 0, 1 or 2 wherein the ligand or ligand blend comprises one or more of (i) a bidentate biphosphite ligand of formula (III), (R12—X12)(R13—X13)P—X14—Y—X24—P(X22—R22)(X23—R23), (ii) a tridentate triphosphite ligand of formula (IIIA) (R12—X12)(R13—X13)P—X14—Y—X32—P(X34—R34)—(X33—Y2—K24—P(X23—R23)—(X22—R22) or (iii) a monodentate phosphite ligand of formula (IV) P(X1—R1)(X2—R2)(X3—R3) where each X is oxygen or a bond and each Y is an optionally substituted C6-C20 arylene, followed by separation of the ligand hydrolysis products.

公开(公告)号：US20150158812A1

公开(公告)日：2015-06-11

申请号：US14404068

申请日：2013-05-24

Applicant: INVISTA NORTH AMERICA S.A R.L.

Inventor： Sudhir Aki ,  William J. Tenn, III ,  Thomas E. Vos

IPC: C07C253/30

CPC classification number: C07C253/30 ,  C07F9/145 ,  C07F9/4006 ,  C07F9/65744 ,  C07F15/04

Abstract: A process of stabilizing a bidentate or tridentate phosphorus-based phosphite ester ligand or mixture thereof in a hydrocyanation reaction milieu comprising water, wherein the ligand or ligand mixture comprises one or more of (i) a bidentate biphosphite ligand of formula (III), (R12—X12) (R13—X13) P—X14—Y—X24—P(X22—R22) (X23—R23) or (ii) a tridentate triphosphite ligand of formula (IIIA) (R12—X12) (R13—X13) P—X14—Y—X32—P(X34—R34)—(X33—Y2—R24—P(X23—R23)—(X22—R22) where each X is oxygen or a bond and each Y is an optionally substituted C6-C20 arylene group, comprising admixing the bidentate and/or tridentate with a stabilizing amount of one or more monodentate phosphite ligand of formula P(X1—R1)(X2—R2)(X3—R3) where each X is oxygen or a bond, wherein the monodentate ligand has a rate of hydrolysis greater than the rate of hydrolysis of the bidentate or tridentate ligand in the presence of water in a hydrocyanation reaction milieu, and thereby preserve concentrations and proportions of the bidentate and/or tridentate ligand(s) in the ligand blend.

Abstract translation: 在包含水的氢化氰化反应环境中稳定二齿或三齿磷基亚磷酸酯配体或其混合物的方法，其中配体或配体混合物包含（i）式（III）的二齿二亚磷酸酯配体，（ R12-X12）（R13-X13）P-X14-Y-X24-P（X22-R22）（X23-R23）或（ii）式（IIIA）（R12-X12）（R13-X13）的三齿三亚磷酸酯配体 ）X-X-14-Y-X32-P（X34-R34） - （X33-Y2-R24-P（X23-R23） - （X22-R22）其中X为氧或键， C6-C20亚芳基，其包括将二齿和/或三齿与稳定量的一种或多种式P（X1-R1）（X2-R2）（X3-R3）的单齿亚磷酸酯配体（X-R 3）混合，其中每个X为氧或 键，其中所述单齿配体的水解速率大于在氢氰化反应环境中的水存在下二齿或三齿配体的水解速率，并且th 在配体共混物中保留双齿和/或三齿配体的浓度和比例。