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公开(公告)号:WO2019152753A8
公开(公告)日:2019-08-08
申请号:PCT/US2019/016211
申请日:2019-02-01
Inventor: COMBE, Jonathan, Paul , FOSTER, Alexander, Brett , BARMAN, Arghya
Abstract: Methods and materials for the production of hydroxy fatty acid anions, including 2-hydroxyisobutyric acid (2-HIBA), and/or derivatives thereof and compounds related thereto are provided. Also provided are products produced in accordance with these methods and materials.
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公开(公告)号:WO2019213017A1
公开(公告)日:2019-11-07
申请号:PCT/US2019/029795
申请日:2019-04-30
Inventor: FOSTER, Alexander, Brett , COMBE, Jonathan, Paul , BARMAN, Arghya
IPC: C12N1/20 , C12N9/88 , C12N9/04 , C12N15/52 , C12N9/12 , C12N9/02 , C12N9/06 , C12N9/10 , C12N9/00 , C12P5/02 , C12P7/04 , C12P7/18 , C12P7/40 , C12P7/42 , C12P7/44 , C12P13/04 , C12P13/00 , C12P7/64 , C12P1/04
Abstract: Methods for increasing carbon-based chemical product yield in an organism by perturbing redox balance in an organism as well as nonnaturally occurring organisms with perturbed redox balance and methods for their use in producing carbon-based chemical products are provided.
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公开(公告)号:WO2019006255A1
公开(公告)日:2019-01-03
申请号:PCT/US2018/040213
申请日:2018-06-29
Applicant: INVISTA NORTH AMERICA S.A.R.L.
Inventor: CARTMAN, Stephen, Thomas , COMBE, Jonathan, Paul , PATTENDEN, Leonard, Keith , SHAW, Andrew , ZAMPINI, Massimiliano
IPC: C07C11/18 , C07F9/09 , C08F136/08 , C12N1/15
CPC classification number: C12P5/007 , C12N9/0006 , C12N9/1029 , C12N9/1205 , C12N9/1229 , C12N9/88 , C12N9/90 , C12N15/746 , C12Y101/01034 , C12Y203/01009 , C12Y203/0301 , C12Y207/01036 , C12Y207/04002 , C12Y401/01033 , C12Y401/03 , C12Y402/03027 , C12Y503/03002
Abstract: The present invention relates to recombinant host cells polynucleotides and polypeptides, methods for their production, and methods for their use in production of hydrocarbons. Disclosed herein are methods, compositions and hosts for synthesizing hydrocarbons and derivatives thereof. In one non-limiting embodiment, the methods, compositions and hosts are used to synthesize hydrocarbons comprising one or more isoprene units as depicted in Formula I as well as salts or derivatives thereof. An aspect of the present invention relates to a genetically engineered host capable of producing hydrocarbons or derivatives thereof via a mevalonate (MVA) pathway.
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