公开(公告)号：WO2014078613A8

公开(公告)日：2014-05-22

申请号：PCT/US2013/070220

申请日：2013-11-15

Applicant: ISP INVESTMENTS INC.

Inventor： PROSISE, William, E. ,  GIANNONE, Gillian ,  LYNN, Jeffrey ,  GRIGORAS, Cristian

IPC: A61K8/81

Abstract: The present invention provides oral care compositions for treating tooth sensitivity. The composition comprises a synergistic mixture containing a copolymer having at least one repeating unit of alkyl vinyl ether functionality and a monomer having at least one repeating unit of ethylenically unsaturated dicarboxylic acid or anhydride functionality present in an amount of about 0.1 to about 50% (w /w) of the total mixture; and a homo polymer having repeating unit of alkyl vinyl ether functionality present in an amount of about 0.1 to about 50% (w / w) of the total mixture. These synergistic mixtures of polymers act as barriers for dentin flow and reduce pain and discomfort caused by tooth sensitivity and exhibits at least 60% average reduction in dentin flow.

公开(公告)号：WO2013082359A1

公开(公告)日：2013-06-06

申请号：PCT/US2012/067193

申请日：2012-11-30

Applicant: ISP INVESTMENTS INC. ,  GRIGORAS, Cristian ,  PLOCHOCKA, Krystyna ,  MUSA, Osama, M. ,  SHIH, Jenn

Inventor： GRIGORAS, Cristian ,  PLOCHOCKA, Krystyna ,  MUSA, Osama, M. ,  SHIH, Jenn

IPC: C08F2/00

CPC classification number: C08F220/08 ,  C08F110/10 ,  C08F216/14 ,  C08F216/18 ,  C08F222/06 ,  C08F226/06 ,  C08F226/10 ,  C08F2810/20

Abstract: Branched polymers are prepared from at least (A) at least one monomer having an electron donor moiety, (B) at least one monomer having an electron acceptor moiety, and (C) at least one multifunctional branching agent comprising a urea moiety and at least two N-vinyl groups. The branched polymers are least 20% (by weight) soluble in a solvent for which the corresponding polymer of equal molecular weight made without said multifunctional branching agent is at least 20% (by weight) soluble. Due in part to the wide range of chemistries and solubility and rheological properties, the branched polymers find application in personal care, pharmaceutical/nutritional, and performance chemicals compositions.

Abstract translation: 支链聚合物由至少一种至少一种具有电子供体部分的单体，（B）至少一种具有电子受体部分的单体，和（C）至少一种包含脲部分的至少一种多官能支化剂，至少 两个N-乙烯基。 支链聚合物可溶于不含所述多官能支化剂的相等分子量的相应聚合物至少为20重量％（重量）可溶的溶剂中的至少20重量％。 部分由于化学物质的广泛范围和溶解度和流变性能，支链聚合物可用于个人护理，药物/营养和性能化学成分。

公开(公告)号：WO2015142832A1

公开(公告)日：2015-09-24

申请号：PCT/US2015/020939

申请日：2015-03-17

Applicant: ISP INVESTMENTS INC.

Inventor： MUSA, Osama M. ,  NACHARAJU, Krishnamurthy ,  GRIGORAS, Cristian

IPC: A61Q11/00 ,  A61K8/72 ,  A61K8/81

CPC classification number: C08F8/32 ,  A61K8/8164 ,  A61Q5/00 ,  A61Q5/02 ,  A61Q11/00 ,  A61Q19/00 ,  A61Q19/10 ,  C08F22/36 ,  C08F122/40 ,  C08F222/06 ,  C08F222/40 ,  C08L33/24 ,  C09D131/04 ,  C08F216/14

Abstract: The present invention provides amic acids and imides derived from a polymer comprising: (a) maleic anhydride, (b) a first C 1 -C 7 alkyl vinyl ether monomer, and (c) a second C 8 -C 30 alkyl vinyl ether monomer, wherein the polymer contains an amic acid or an imide group. The polymers containing an amic acid or an imide group of the invention may be employed in a wide variety of compositions, particularly in oral care compositions. Non-limiting generic structures of the amidic polymers are set out below: (I) wherein R 1 -R 3 , M, a, b, c, d, e, and f are defined herein.

Abstract translation: 本发明提供了衍生自聚合物的酰胺酸和酰亚胺，其包含：（a）马来酸酐，（b）第一C1-C7烷基乙烯基醚单体和（c）第二C8-C30烷基乙烯基醚单体，其中所述聚合物 含有酰胺酸或酰亚胺基。 含有本发明的酰胺酸或酰亚胺基的聚合物可以用于多种组合物中，特别是在口腔护理组合物中。 酰胺聚合物的非限制性通用结构如下：（I）其中R1-R3，M，a，b，c，d，e和f如本文所定义。

公开(公告)号：EP2919750A1

公开(公告)日：2015-09-23

申请号：EP13854702.1

申请日：2013-11-15

Applicant: Isp Investments Inc.

Inventor： PROSISE, William, E. ,  GIANNONE, Gillian ,  LYNN, Jeffrey ,  GRIGORAS, Cristian

IPC: A61K8/81

CPC classification number: A61K8/8164 ,  A61K8/8129 ,  A61K2800/594 ,  A61K2800/92 ,  A61Q11/00

Abstract: The present invention provides oral care compositions for treating tooth sensitivity. The composition comprises a synergistic mixture containing a copolymer having at least one repeating unit of alkyl vinyl ether functionality and a monomer having at least one repeating unit of ethylenically unsaturated dicarboxylic acid or anhydride functionality present in an amount of about 0.1 to about 50% (w /w) of the total mixture; and a homo polymer having repeating unit of alkyl vinyl ether functionality present in an amount of about 0.1 to about 50% (w / w) of the total mixture. These synergistic mixtures of polymers act as barriers for dentin flow and reduce pain and discomfort caused by tooth sensitivity and exhibits at least 60% average reduction in dentin flow.