公开(公告)号：US12194137B2

公开(公告)日：2025-01-14

申请号：US17513484

申请日：2021-10-28

Applicant: Industrial Technology Research Institute

Inventor： Yin-Lung Han ,  Chieh-Lun Cheng ,  Kai-Chun Fan ,  Pei-Jyuan Gao ,  Bo-Han Chen

IPC: A61K8/99 ,  A61K8/65 ,  A61K8/66 ,  A61K8/9778 ,  A61K8/9789 ,  A61K8/98 ,  A61Q5/04

Abstract: A biological hair shape change composition including a macromolecular component, a small molecular component and an alkali agent component is provided. The macromolecular component includes a protease belonging to the class of alkaline proteases, and the small molecular component includes a peptide with reduction activity. Both the macromolecular component and the small molecular component are obtained from a fermentation product of Bacillus licheniformis and a keratin and/or keratin polymer-containing medium. Molecular weights of ingredients in the macromolecular component are greater than or equal to 3 kDa and are 3-1000 kDa, and molecular weights of ingredients in the small molecular component are less than 3 kDa and are 0.01-2.99 kDa.

公开(公告)号：US11414658B2

公开(公告)日：2022-08-16

申请号：US16710632

申请日：2019-12-11

Applicant: Industrial Technology Research Institute

Inventor： Kai-Chun Fan ,  Yin-Lung Han ,  Pei-Jyuan Gao ,  Yong-Yang Lin ,  Chieh-Lun Cheng ,  Chien-Chang Huang ,  Yung-Ho Chang ,  Chia-Long Lin ,  I-Son Ng ,  Bo-Han Chen

IPC: C12Q1/68 ,  C12N15/11 ,  C12Q1/6876

Abstract: A tracer particle is provided. The tracer particle includes: a core structure; a nucleic acid molecule immobilized on the core structure; and a shell layer covering the core structure and the nucleic acid molecule; wherein the core structure has a first porosity, the shell layer has a second porosity, and the first porosity is greater than the second porosity.