-
公开(公告)号:US20140286929A1
公开(公告)日:2014-09-25
申请号:US14213970
申请日:2014-03-14
Applicant: Intermune, Inc.
Inventor: Karl Kossen , Xiaoli Qin , Sharlene R. Lim , Scott S. Seiwert , Donald Ruhrmund
IPC: G01N33/543 , A61K38/45 , A61K38/46 , A61K38/17 , A61K38/48
CPC classification number: G01N33/6893 , C12Q1/6883 , C12Q2600/118 , C12Q2600/158 , G01N33/6854 , G01N2800/12
Abstract: Provided herein are novel biomarkers for the identification, prediction or monitoring of fibrotic pulmonary diseases (e.g. idiopathic pulmonary fibrosis (IPF)). The biomarkers provided herein may further be used for therapeutic treatment of IPF.
Abstract translation: 本文提供了用于鉴定,预测或监测纤维化性肺疾病(例如特发性肺纤维化(IPF))的新型生物标志物。 本文提供的生物标志物可进一步用于IPF的治疗性治疗。
-
公开(公告)号:US20170314074A1
公开(公告)日:2017-11-02
申请号:US15351719
申请日:2016-11-15
Applicant: Intermune, Inc.
Inventor: Karl Kossen , Sharlene R. Lim , Scott D. Seiwert , Donald Ruhrmund
IPC: C12Q1/68
CPC classification number: C12Q1/6883 , A61K31/7088 , A61K45/06 , C12Q2600/118 , C12Q2600/158 , G16B99/00 , Y02A50/411 , Y02A90/24 , Y02A90/26
Abstract: Provided herein are, inter alia, methods and biomarkers to determine if a patient has or is at risk for developing an LPA-associated disease, to indicate the progressiveness of the disease, and/or to facilitate evaluation of responsiveness to therapy. Compositions and kits including the biomarker proteins and biomarker RNAs provided herein are further provided.
-
公开(公告)号:US09726677B2
公开(公告)日:2017-08-08
申请号:US14213970
申请日:2014-03-14
Applicant: Intermune, Inc.
Inventor: Karl Kossen , Xiaoli Qin , Sharlene R. Lim , Scott S. Seiwert , Donald Ruhrmund
CPC classification number: G01N33/6893 , C12Q1/6883 , C12Q2600/118 , C12Q2600/158 , G01N33/6854 , G01N2800/12
Abstract: Provided herein are novel biomarkers for the identification, prediction or monitoring of fibrotic pulmonary diseases (e.g. idiopathic pulmonary fibrosis (IPF)). The biomarkers provided herein may further be used for therapeutic treatment of IPF.
-
-