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公开(公告)号：AU2016374571B2
公开(公告)日：2021-05-06
申请号：AU2016374571
申请日：2016-12-16
Applicant: JANSSEN PHARMACEUTICA NV
Inventor： ANDRÉS-GIL JOSÉ IGNACIO , VAN GOOL MICHIEL LUC MARIA , BORMANS GUY MAURITS R , VERBEEK JOOST
IPC: C07D487/04 , A61K51/04 , A61K101/02 , C07B59/00
Abstract: The present invention relates to novel, radiolabelled mGluR2/3 ligands, selective 5 versus other mGlu receptors, which are useful for imaging and quantifying the metabotropic glutamate receptors mGlu2 and 3 in tissues, using positron-emission tomography (PET). The invention is also directed to compositions comprising such compounds, to processes for preparing such compounds and compositions, to the use of such compounds and compositions for imaging a tissue, cells or a mammal, in vitro or 10 in vivo and to precursors of said compounds.
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公开(公告)号：AU2015357169B2
公开(公告)日：2021-03-04
申请号：AU2015357169
申请日：2015-12-02
Applicant: JANSSEN PHARMACEUTICA NV
Inventor： VAN GOOL MICHIEL LUC MARIA , ANDRES-GIL JOSE IGNACIO , ALCAZAR-VACA MANUEL JESUS , BORMANS GUY MAURITS R , CELEN SOFIE JEANNE LEOPOLDINE , VERBEEK JOOST
IPC: C07D487/04 , A61K51/04 , A61P25/18 , A61P25/24
Abstract: The present invention relates to novel, selective, radiolabelled mGluR2 ligands which are useful for imaging and quantifying the metabotropic glutamate receptor mGluR2 in tissues, using positron-emission tomography (PET). The invention is also directed to compositions comprising such compounds, to processes for preparing such compounds and compositions, to the use of such compounds and compositions for imaging a tissue, cells or a mammal, in vitro or in vivo and to precursors of said compounds.
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公开(公告)号：DK3389727T3
公开(公告)日：2020-11-02
申请号：DK16812961
申请日：2016-12-16
Applicant: JANSSEN PHARMACEUTICA NV
Inventor： VERBEEK JOOST , BORMANS GUY MAURITS R , ANDRÉS-GIL JOSÉ IGNACIO , VAN GOOL MICHIEL LUC MARIA
IPC: A61K51/04 , A61K101/02 , C07B59/00 , C07D487/04
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公开(公告)号：AU2016374571A1
公开(公告)日：2018-05-17
申请号：AU2016374571
申请日：2016-12-16
Applicant: JANSSEN PHARMACEUTICA NV
Inventor： ANDRÉS-GIL JOSÉ IGNACIO , VAN GOOL MICHIEL LUC MARIA , BORMANS GUY MAURITS R , VERBEEK JOOST
IPC: C07D487/04 , A61K51/04 , A61K101/02 , C07B59/00
Abstract: The present invention relates to novel, radiolabelled mGluR2/3 ligands, selective 5 versus other mGlu receptors, which are useful for imaging and quantifying the metabotropic glutamate receptors mGlu2 and 3 in tissues, using positron-emission tomography (PET). The invention is also directed to compositions comprising such compounds, to processes for preparing such compounds and compositions, to the use of such compounds and compositions for imaging a tissue, cells or a mammal, in vitro or 10 in vivo and to precursors of said compounds.
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公开(公告)号：CA3003998A1
公开(公告)日：2017-06-22
申请号：CA3003998
申请日：2016-12-16
Applicant: JANSSEN PHARMACEUTICA NV
Inventor： ANDRES-GIL JOSE IGNACIO , VAN GOOL MICHIEL LUC MARIA , BORMANS GUY MAURITS R , VERBEEK JOOST
IPC: A61K51/04 , C07B59/00 , C07D487/04
Abstract: The present invention relates to novel, radiolabelled mGluR2/3 ligands, selective 5 versus other mGlu receptors, which are useful for imaging and quantifying the metabotropic glutamate receptors mGlu2 and 3 in tissues, using positron-emission tomography (PET). The invention is also directed to compositions comprising such compounds, to processes for preparing such compounds and compositions, to the use of such compounds and compositions for imaging a tissue, cells or a mammal, in vitro or 10 in vivo and to precursors of said compounds.
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Patent Agency Ranking
公开(公告)号：HUE050665T2
公开(公告)日：2020-12-28
申请号：HUE16812961
申请日：2016-12-16
Applicant: JANSSEN PHARMACEUTICA NV
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公开(公告)号：AU2016374568B2
公开(公告)日：2020-08-27
申请号：AU2016374568
申请日：2016-12-16
Applicant: JANSSEN PHARMACEUTICA NV
Inventor： ANDRES-GIL JOSE IGNACIO , VAN GOOL MICHIEL LUC MARIA , BORMANS GUY MAURITS R , VERBEEK JOOST
IPC: C07D487/04 , A61K51/04 , A61K101/02 , C07B59/00
Abstract: The present invention relates to novel, radiolabeled mGluR2/3 ligands, selective versus other mGlu receptors which are useful for imaging and quantifying the metabotropic glutamate receptor mGlu2 and 3 in tissues, using positron-emission tomography (PET). The invention is also directed to compositions comprising such compounds, to processes for preparing such compounds and compositions, to the use of such compounds and compositions for imaging a tissue, cells or a mammal, in vitro or in vivo and to precursors of said compounds.
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公开(公告)号：AU2016374568A1
公开(公告)日：2018-05-17
申请号：AU2016374568
申请日：2016-12-16
Applicant: JANSSEN PHARMACEUTICA NV
Inventor： ANDRES-GIL JOSE IGNACIO , VAN GOOL MICHIEL LUC MARIA , BORMANS GUY MAURITS R , VERBEEK JOOST
IPC: C07D487/04 , A61K51/04 , A61K101/02 , C07B59/00
Abstract: The present invention relates to novel, radiolabeled mGluR2/3 ligands, selective versus other mGlu receptors which are useful for imaging and quantifying the metabotropic glutamate receptor mGlu2 and 3 in tissues, using positron-emission tomography (PET). The invention is also directed to compositions comprising such compounds, to processes for preparing such compounds and compositions, to the use of such compounds and compositions for imaging a tissue, cells or a mammal, in vitro or in vivo and to precursors of said compounds.
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公开(公告)号：CA3003962A1
公开(公告)日：2017-06-22
申请号：CA3003962
申请日：2016-12-16
Applicant: JANSSEN PHARMACEUTICA NV
Inventor： ANDRES-GIL JOSE IGNACIO , VAN GOOL MICHIEL LUC MARIA , BORMANS GUY MAURITS R , VERBEEK JOOST
IPC: A61K51/04 , C07B59/00 , C07D487/04
Abstract: The present invention relates to novel, radiolabeled mGluR2/3 ligands, selective versus other mGlu receptors which are useful for imaging and quantifying the metabotropic glutamate receptor mGlu2 and 3 in tissues, using positron-emission tomography (PET). The invention is also directed to compositions comprising such compounds, to processes for preparing such compounds and compositions, to the use of such compounds and compositions for imaging a tissue, cells or a mammal, in vitro or in vivo and to precursors of said compounds.
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公开(公告)号：CA2967542A1
公开(公告)日：2016-06-09
申请号：CA2967542
申请日：2015-12-02
Applicant: JANSSEN PHARMACEUTICA NV
Inventor： VAN GOOL MICHIEL LUC MARIA , ANDRES-GIL JOSE IGNACIO , ALCAZAR-VACA MANUEL JESUS , BORMANS GUY MAURITS R , CELEN SOFIE JEANNE LEOPOLDINE , VERBEEK JOOST
Abstract: The present invention relates to novel, selective, radiolabelled mGluR2 ligands which are useful for imaging and quantifying the metabotropic glutamate receptor mGluR2 in tissues, using positron-emission tomography (PET). The invention is also directed to compositions comprising such compounds, to processes for preparing such compounds and compositions, to the use of such compounds and compositions for imaging a tissue, cells or a mammal, in vitro or in vivo and to precursors of said compounds.
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