公开(公告)号：JP2003252845A

公开(公告)日：2003-09-10

申请号：JP2002056264

申请日：2002-03-01

Applicant: JAPAN SCIENCE & TECH CORP

Inventor： ISHIHARA KAZUAKI ,  YAMAMOTO TAKASHI

IPC: C07D213/85 ,  C07B61/00 ,  C07C253/00 ,  C07C253/20 ,  C07C255/03 ,  C07C255/33 ,  C07C255/34 ,  C07C255/46 ,  C07C255/47 ,  C07C255/50 ,  C07C255/52 ,  C07C255/54

Abstract: PROBLEM TO BE SOLVED: To provide a general method for easily producing a nitrile by which the nitrile regardless of aliphatic and aromatic is obtained from a primary amide or an aldoxime without requiring a large amount of a dehydrating agent and a severe condition, and to provide a catalyst for producing the nitrile, enabling the nitrile to be easily obtained from the primary amide or the aldoxime. SOLUTION: The primary amide or the aldoxime is reacted in the presence of a solvent by using a seven-valent rhenium compound as a condensation catalyst. The seven-valent rhenium compound is preferably rhenium (VII) peroxide, more preferably trimethyl-silyl-rhenium (VII) peroxide. The nitrile is obtained by the reaction in a nonpolar solvent or a low polar solvent by heating and refluxing the reaction mixture while removing water in an azeotropic state from the reaction system. COPYRIGHT: (C)2003,JPO

公开(公告)号：JP2001270939A

公开(公告)日：2001-10-02

申请号：JP2000087495

申请日：2000-03-27

Applicant: JAPAN SCIENCE & TECH CORP

Inventor： ISHIHARA KAZUAKI ,  YAMAMOTO TAKASHI

IPC: C08G69/04 ,  C08G69/28 ,  C08G73/10

Abstract: PROBLEM TO BE SOLVED: To provide a process a prepare a polyamide, a polyimide, and a polyamide-imide which are easy to purify after the reactions, especially an aromatic polyamide (an aramide), an aromatic polyimide, and an aromatic polyamide-imide which are said to be difficult to synthesize by a direct polycondensation, from a polycarboxylic acid and a polyamine by a direct polycondensation reaction with heating in a high yield without side reactions such as discoloring to black or the like. SOLUTION: A polyamide, a polyimide, or polyamide-imide is obtained in a high yield by polycondensation reaction of an aromatic dicarboxylic acid, an aromatic tetracarboxylic acid or an aromatic tricarboxylic acid with an aromatic diamine in the presence of a polar solvent such as N-butylpyrrolidinone or the like or a mixed solvent of the polar solvent and a nonpolar solvent, using N-methyl-4-pyridium borate iodide and sodium tetrakis(3,5-bis(trifluoromethyl)phenyl)borate as its polycondensation catalysts.

公开(公告)号：JP2002338539A

公开(公告)日：2002-11-27

申请号：JP2001283218

申请日：2001-09-18

Applicant: JAPAN SCIENCE & TECH CORP

Inventor： ISHIHARA KAZUAKI ,  YAMAMOTO TAKASHI

IPC: B01J31/02 ,  B01J31/06 ,  B01J31/10 ,  C07B61/00 ,  C07C17/14 ,  C07C17/26 ,  C07C29/38 ,  C07C29/44 ,  C07C33/30 ,  C07C41/50 ,  C07C41/56 ,  C07C43/303 ,  C07C45/51 ,  C07C45/64 ,  C07C45/67 ,  C07C45/72 ,  C07C49/83 ,  C07C67/08 ,  C07C69/78 ,  C07C313/04 ,  C08F8/34

Abstract: PROBLEM TO BE SOLVED: To provide a solid acid catalyst which can improve the efficiency of a reaction proceeding in the presence of a Broensted acid or a Lewis acid catalyst, for example, facilitates the benzoylation of an alcohol, can easily be recovered or recycled, and is excellent from the viewpoints of toxicity, environments and the like. SOLUTION: This polystyrene support type arylbis(perfluoroalkylsulfonyl) methane represented by general formula [3] (R is a substituted or non- substituted arylene; Rf and Rf are each independently a perfluoroalkyl) is obtained by supporting the para-position of an arylbis(perfluoroalkylsulfonyl) methane represented by general formula [1] (R is a substituted or non- substituted aryl), such as pentafluorophenylbis(perfluoroalkylsulfonyl)methane, with polystyrene resin.

公开(公告)号：JP2001064207A

公开(公告)日：2001-03-13

申请号：JP24052799

申请日：1999-08-26

Applicant: JAPAN SCIENCE & TECH CORP

Inventor： SAITO SUSUMU ,  YAMAMOTO TAKASHI

IPC: C07B37/04 ,  C07B53/00 ,  C07C37/11 ,  C07C39/12

Abstract: PROBLEM TO BE SOLVED: To provide a method for readily carrying out an aromatic asymmetric coupling reaction capable of providing an aromatic cross-coupled body in good yield. SOLUTION: This method for carrying out an asymmetric coupling reaction between different two kinds of aromatic compounds comprises reacting an aromatic lead compound having lead atom bonded to an aromatic ring, with a metal phenoxide compound in the presence of a tertiary amine compound having a fixed conformation hardly causing the inversion of an unshared electron pair of the nitrogen atom to mutually form the bond between aromatic rings to provide the objective asymmetrical compound.

公开(公告)号：JP2000198778A

公开(公告)日：2000-07-18

申请号：JP166599

申请日：1999-01-07

Applicant: JAPAN SCIENCE & TECH CORP

Inventor： ISHIHARA KAZUAKI ,  YAMAMOTO TAKASHI

IPC: C07D307/92 ,  B01J31/22 ,  C07D311/74 ,  C07D311/80 ,  C07F7/22

Abstract: PROBLEM TO BE SOLVED: To obtain the subject compound useful for the production of an ambergris, or the like, in one-step synthetic reaction in an excellent chemical yield, stereo-selectively, and in a good efficiency by effecting a specific asymmetric catalyst on a polyolefin so as to perform an intramolecular cyclization reaction. SOLUTION: This method for producing an optically active cyclic compound comprises effecting a complex formed by coordinating a metal halide compound (preferably tin tetrachloride) with an optically active binaphthol derivative as an asymmetric catalyst to preferably a polyolefin such as a polyprenoid (e.g.; homofarnesol) so as to perform an intramolecular cyclization reaction at (-)78-25 deg.C to obtain preferably the objective compound as a compound of formula I. The above complex is preferably a compound of formula II (R is H or isopropyl), or the like.

公开(公告)号：JP2002121170A

公开(公告)日：2002-04-23

申请号：JP2000314712

申请日：2000-10-16

Applicant: JAPAN SCIENCE & TECH CORP

Inventor： ISHIHARA KAZUAKI ,  YAMAMOTO TAKASHI

IPC: B01J27/135 ,  B01J31/02 ,  B01J31/22 ,  B01J31/38 ,  C07B61/00 ,  C07C67/08 ,  C07C69/24 ,  C07C69/612 ,  C07C69/618 ,  C07C69/734 ,  C07C69/75 ,  C07C69/753 ,  C07C69/78 ,  C07C201/14 ,  C07C205/56 ,  C07C327/20 ,  C07C327/22 ,  C07D309/30 ,  C07D313/04 ,  C08G63/81 ,  C08G63/85

Abstract: PROBLEM TO BE SOLVED: To provide a method for producing a (thio)ester condensate by catalytic esterification between equimolar amounts of a carboxylic acid and an alcohol or by catalytic thioesterification between a carboxylic acid and an equimolar or small excess amount of a thiol, thus hopeful as an industrial method needing mass synthesis from the standpoint of green chemistry. SOLUTION: This method for producing a (thio)ester condensate comprises the following process: a direct condensation reaction is made between a carboxylic acid and an equimolar amount of an alcohol or a small excess amount of a thiol in a nonpolar solvent such as toluene in a deoxygenation atmosphere under reflux while heating in the presence of a (poly)condensation catalyst consisting of a tetravalent hafnium compound represented by hafnium (IV) chloride, especially hafnium (IV) chloride.(THF)2 or hafnium (IV) t-butoxide to synthesize the objective monomeric (thio)ester or poly(thio)ester; wherein it is preferable that in making the reflux under heating using the nonpolar solvent, the azeotropic water is eliminated from the reaction system.

公开(公告)号：JP2002265472A

公开(公告)日：2002-09-18

申请号：JP2001070184

申请日：2001-03-13

Applicant: JAPAN SCIENCE & TECH CORP

Inventor： ISHIHARA KAZUAKI ,  YAMAMOTO TAKASHI

IPC: C07D211/16 ,  B01J31/14 ,  C07B61/00 ,  C07C231/02 ,  C07C233/00 ,  C07F5/02

Abstract: PROBLEM TO BE SOLVED: To provide a compound which has excellent catalytic activity, can be recovered in high recovery ratio, can easily be recycled, and is useful as a new amide dehydration condensatiotion catalyst. SOLUTION: The perfluoroalkylphenylboric acid of the general formula 1 [Rf is a 2 to 30C perfluoroalkyl group substituted at at least one of the 3-, 4-, and 5-positions; (n) is an integer of 1 to 5; when (n) is >=2, Rf groups may be identical or different each others, such as 3,5-bis(perfluorodecyl)phenylboric acid or 4-perfluorodecylphenylboric acid.

公开(公告)号：JP2002088046A

公开(公告)日：2002-03-27

申请号：JP2000281042

申请日：2000-09-14

Applicant: JAPAN SCIENCE & TECH CORP

Inventor： HOSHINO YUJIRO ,  YAMAMOTO TAKASHI ,  OISHI RIKI

IPC: C07D221/14 ,  B01J31/02 ,  C07B53/00 ,  C07B61/00 ,  C07C259/06 ,  C07D301/19 ,  C07D303/14

Abstract: PROBLEM TO BE SOLVED: To provide an optically active hydroxamic acid, useful as a new optically active hydroxamic acid ligand which is used as an asymmetric oxidation reaction catalyst including an asymmetric epoxidation reaction catalyst, especially useful as the new optically active hydroxamic acid ligand having an amino acid as a main skeletal structure. SOLUTION: This optically active hydroxamic acid of the formula (I) (R1 is a substituent containing no functional group; R2 and R3 are each a protective group on N, or may mutually bond to form the protective group; and R44 is a substituent containing no functional group) is obtained by reacting a free amino acid with a carboxylic anhydride, such as phthalic, 2,3-dimethylmalonic and 2,3-naphthalenedicarboxylic anhydride, and then reacting the formed amino acid in which a protective group is formed on the nitrogen atom of the amino acid with a hydroxylamine, such as diarylmethylhydroxylamine of the formula (III). When the optically active hydroxamic acid of the formula (II) is, for example, used in asymmetric epoxidation reaction of allyl alcohol where a vanadium catalyst is used, epoxy alcohol is obtained with a high selectivity (a yield of 96%; an enantioselectivity of 95%).