公开(公告)号：US20180104686A1

公开(公告)日：2018-04-19

申请号：US15567431

申请日：2016-06-07

Applicant: JAPAN SCIENCE AND TECHNOLOGY AGENCY

Inventor： Rikiya WATANABE ,  Hiroyuki NOJI ,  Naoki SOGA

IPC: B01L3/00 ,  G01N33/487 ,  B01J19/00

CPC classification number: B01L3/5085 ,  B01J19/0046 ,  B01J2219/00317 ,  B01J2219/00331 ,  B01J2219/00619 ,  B01J2219/00621 ,  B01J2219/00653 ,  B01J2219/00702 ,  B01J2219/00725 ,  B01J2219/00734 ,  B01L2200/0642 ,  B01L2200/0647 ,  B01L2200/0689 ,  B01L2200/12 ,  B01L2200/142 ,  B01L2300/0645 ,  B01L2300/0819 ,  B01L2300/0861 ,  B01L2300/0877 ,  B01L2300/165 ,  C12M1/00 ,  G01N33/48 ,  G01N33/48707

Abstract: A high-density micro-chamber array has a translucent flat substrate, a hydrophobic layer in which a plurality of micro-chambers are provided, and a lipid bilayer membrane formed in each of the openings of the micro-chambers, wherein an electrode is provided in each of the micro-chambers, and when the side of the substrate on which the hydrophobic layer is provided is directed upward, the micro-chamber array is configured such that with at least one of the following A) and B) being met, light entering the substrate from below is transmitted through the substrate and penetrates into the micro-chambers' interiors, and light entering the substrate from the micro-chambers' interiors is transmitted through the substrate and escapes toward below the substrate. A) The electrode is provided on an inner side surface of each of the micro-chambers. B) The electrode is transparent and provided on a bottom surface of each of the micro-chambers.