公开(公告)号：US09958429B2

公开(公告)日：2018-05-01

申请号：US15033224

申请日：2014-11-06

Applicant: JAPAN SCIENCE AND TECHNOLOGY AGENCY

Inventor： Hiroshi Sunami ,  Ikuko Yokota

IPC: G01N33/00 ,  G01N33/483 ,  G01N33/50 ,  C12N5/00 ,  C12M1/00

CPC classification number: G01N33/4833 ,  C12M47/04 ,  C12N5/0068 ,  C12N2535/00 ,  G01N33/5005

Abstract: The present invention provides a control substrate for controlling a movement direction of animal cells. The control substrate for controlling a movement direction of animal cells has a surface which includes a plurality of grooves, the grooves are formed from a bottom between opposing walls and the opposing walls forming the grooves wherein the walls include a plurality of columnar protrusions. Vertex parts of the columnar protrusion are formed to face between vertex parts of two columnar protrusions formed in the opposing wall and such vertex parts face the same direction.

公开(公告)号：US10513683B2

公开(公告)日：2019-12-24

申请号：US15104733

申请日：2014-12-16

Applicant: Japan Science and Technology Agency

Inventor： Hiroshi Sunami ,  Ikuko Yokota

IPC: C12N5/00 ,  C12M1/00

Abstract: A structure used for animal cells is provided which includes an elastic body layer having a flat surface on which animal cells are left. The elastic body layer has a surface whose elasticity is changed by partially supporting the elastic body layer from the rear side or by changing a thickness of the elastic body layer.

公开(公告)号：US20160340641A1

公开(公告)日：2016-11-24

申请号：US15104733

申请日：2014-12-16

Applicant: Japan Science and Technology Agency

Inventor： Hiroshi Sunami ,  Ikuko Yokota

IPC: C12N5/00 ,  C12M1/00

CPC classification number: C12N5/0068 ,  C12M23/00 ,  C12M23/26 ,  C12M41/46 ,  C12M47/02 ,  C12M47/04 ,  C12N2535/00 ,  C12N2539/00

Abstract: A structure used for animal cells is provided which includes an elastic body layer having a flat surface on which animal cells are left. The elastic body layer has a surface whose elasticity is changed by partially supporting the elastic body layer from the rear side or by changing a thickness of the elastic body layer.

Abstract translation: 提供了用于动物细胞的结构，其包括具有剩下动物细胞的平坦表面的弹性体层。 弹性体层具有通过从后侧部分地支撑弹性体层或通过改变弹性体层的厚度来改变弹性的表面。

公开(公告)号：US20160274080A1

公开(公告)日：2016-09-22

申请号：US15033224

申请日：2014-11-06

Applicant: JAPAN SCIENCE AND TECHNOLOGY AGENCY

Inventor： Hiroshi Sunami ,  Ikuko Yokota

IPC: G01N33/483

CPC classification number: G01N33/4833 ,  C12M47/04 ,  C12N5/0068 ,  C12N2535/00 ,  G01N33/5005

Abstract: The present invention provides a control substrate for controlling a movement direction of animal cells. The control substrate for controlling a movement direction of animal cells has a surface which includes a plurality of grooves, the grooves are formed from a bottom between opposing walls and the opposing walls forming the grooves wherein the walls include a plurality of columnar protrusions. Vertex parts of the columnar protrusion are formed to face between vertex parts of two columnar protrusions formed in the opposing wall and such vertex parts face the same direction.

Abstract translation: 本发明提供一种用于控制动物细胞移动方向的控制基板。 用于控制动物细胞的移动方向的控制基板具有包括多个凹槽的表面，所述凹槽由形成凹槽的相对壁之间的底部形成，其中壁包括多个柱状突起。 柱状突起的顶点部分形成为面对形成在相对壁中的两个柱状突起的顶点部分，并且这些顶点部分面向相同的方向。