公开(公告)号：WO2007149103A2

公开(公告)日：2007-12-27

申请号：PCT/US2006025443

申请日：2006-06-28

Applicant: KAISER DANIEL E

Inventor： KAISER DANIEL E

IPC: A61B19/00

CPC classification number: A61H9/005 ,  A61B17/1128 ,  A61B17/22 ,  A61B17/2251 ,  A61B2017/00535 ,  A61B2017/00561 ,  A61B2017/00911 ,  A61B2017/22001 ,  A61H9/0057 ,  A61H2201/5082 ,  A61H2201/5087 ,  A61H2201/5089 ,  A61H2205/06 ,  A61H2205/083 ,  A61H2205/10

Abstract: An apparatus for delivering decompressive energy to soft tissues to stimulate cellular expansion through deep penetration of said applied decompressive energy to said soft tissues to stimulate a predetermined reaction to application of said decompressive energy comprising a vessel having an open end and adapted to encompass the soft tissue to be stimulated. A source of decompressive energy in communication with said vessel and a flexible mass affixed to said open end of said vessel to absorb the pressure exerted by delivery of said decompressive energy to said soft tissue, thereby acting as a seal and force diffuser between said vessel and the soft tissue adjacent the periphery of said vessel. A method for the treatment of peripheral vascular disease (PVD) and other medical disorders and ailments that would benefit from increased and enhanced tissue response due to increases in blood flow on macro-vascular, micro-vascular and a collateral level including increased cellular stimulation and response. The method works by surrounding said tissues with a vessel or dome configured to fit over the tissue for treatment with decompressive energy (vacuum forces). The decompressive energy is applied in a controlled manner at a pre-selected level of decompressive force thereby increasing blood flow through the treated tissue. Loading forces generated by applied decompressive energy and the resulting forces generated between the interior of the vessel and the treated tissue which the vessel encompasses are diffused. A method and apparatus for applying decompressive energy to tissue for the selective destruction of cancerous cells is disclose and claimed. The tissue to be treated is enclosed within a vessel subjected to decompressive energy supplied by said decompressive energy source to said vessel. The decompressive energy is applied in a controlled manner to said tissue in at a pre-selected level of decompressive energy. Loading forces generated by applied decompressive energy and the forces generated between the interior of said vessel and said tissue which said vessel encompasses are to be diffused. As disclosed and claimed, a mass of elastic material comprising an inner radius and outer radius with the inner radius forming a seal with said tissue while allowing said tissue to move in relation to said inner radius and a fluid pocket circumf erentially positioned within said elastic mass in combination with a collar positioned at the perimeter of the vessel opening is claimed.

Abstract translation: 一种用于向软组织递送减压能量以通过将所述施加的减压能量深入渗透到所述软组织来刺激细胞扩张的装置，以刺激施加所述减压能量的预定反应，所述减压能量包括具有开口端的容器并且适于包围软组织 被刺激。 与所述容器连通的减压能量源和固定在所述容器的所述开口端的柔性块，以吸收通过将所述减压能量递送到所述软组织而施加的压力，由此用作所述容器和 所述软组织邻近所述容器的周边。 一种用于治疗外周血管疾病（PVD）和其他医学疾病和疾病的方法，其将受益于由于血管，微血管和附属水平的血流增加而增加和增强的组织反应，包括增加的细胞刺激和 响应。 该方法通过用构造成适合于组织上的血管或圆顶围绕所述组织进行工作，以用减压能（真空力）进行治疗。 减压能量以受控的方式以预选的减压力水平施加，从而增加经过处理的组织的血液流量。 通过施加的减压能量产生的装载力和在容器内部和容器所包括的经处理的组织之间产生的所产生的力被扩散。 公开并要求保护用于将选择性破坏癌细胞的减压能量应用于组织的方法和装置。 要处理的组织被包封在经受由所述减压能源供应给所述容器的减压能量的容器内。 减压能量以受控的方式以预先选择的减压能量水平施加到所述组织。 通过施加的减压能量产生的装载力和在所述容器的内部和所述容器所包围的所述组织之间产生的力将被扩散。 如所公开和要求保护的，包括内半径和外半径的弹性材料块，其中内半径与所述组织形成密封，同时允许所述组织相对于所述内半径移动，并且周向地定位在所述弹性质量块内的流体袋 与位于容器开口的周边的套环组合。

公开(公告)号：WO2007002696A2

公开(公告)日：2007-01-04

申请号：PCT/US2006025032

申请日：2006-06-28

Applicant: KAISER DANIEL E

Inventor： KAISER DANIEL E

IPC: A61N5/00

CPC classification number: A61M35/00 ,  A61F13/02 ,  A61H9/005 ,  A61K9/7023

Abstract: An apparatus is disclosed that allows for the delivery of medications and or chemicals for treatment of tissue through permeable dermal patch positioned inside a vessel for use in treating of any particular disease or aliment. The vessel self- adheres through activation of a chemical heater which may be activated by a pull tab exterior of the vessel. Initiation of the chemical reaction generates heat sufficient to raise the air temperature inside the vessel to allow the vessel to auto-generate a vacuum for wound treatment and to aid in sterilization of the wound site. The heated air expands and is evacuates through a one-way valve exterior of the vessel. Cooling of the interior air generates a vacuum inside the vessel to create a suction that holds the vessel in place. Increases blood flow to the treated tissue area, stimulated by the vacuum, facilitates improved delivery of the medication or pharmacological composition to the user. Application of vacuum to the treated tissue disinfects the tissue while providing a bacterial infiltration barrier.

Abstract translation: 公开了一种装置，其允许通过位于容器内部的可渗透的皮肤贴片来递送用于治疗组织的药物和/或化学物质，以用于治疗任何特定的疾病或病症。 容器通过激活化学加热器自身粘附，该化学加热器可以由容器外部的拉片活化。 化学反应的发生产生足以提高容器内的空气温度的热量，以允许容器自动产生用于伤口处理的真空并有助于伤口部位的灭菌。 加热的空气膨胀并通过容器外部的单向阀抽空。 内部空气的冷却在容器内产生真空，以产生将容器保持在适当位置的抽吸。 增加通过真空刺激的经处理的组织区域的血液流动，促进药物或药物组合物向使用者的递送。 将真空应用于经处理的组织，同时提供细菌浸润屏障消毒组织。