公开(公告)号：AT324784T

公开(公告)日：2006-06-15

申请号：AT99968906

申请日：1999-12-16

Applicant: KANEKA CORP

Inventor： ROSE LYNN M ,  PORUBEK DAVID J ,  MONTGOMERY ALAN B

IPC: C07D498/18 ,  A61K9/02 ,  A61K9/14 ,  A61K9/20 ,  A61K9/50 ,  A61K9/52 ,  A61K31/00 ,  A61K31/133 ,  A61K31/42 ,  A61K31/4409 ,  A61K31/4965 ,  A61K31/538 ,  A61K31/5383 ,  A61K31/70 ,  A61K31/7036 ,  A61K31/7048 ,  A61K31/7052 ,  A61K38/00 ,  A61P1/04 ,  A61P11/00 ,  A61P31/04 ,  A61P31/06 ,  A61P31/18 ,  A01N43/40 ,  A61K31/44

Abstract: A method for treatment of bacterial infections with rifalazil administered once-weekly, or twice-weekly. A method for treatment of tuberculosis caused by Mycobacterium tuberculosis, infections caused by Mycobacterium avium complex, infections caused by Chlamydia pneumoniae and infections caused by Helicobacter pylori by administering to a patient suffering from the bacterial infection 1-100 mg of rifalazil once or twice a week. In this dose regimen, the treatment is fast, efficacious and eliminates undesirable secondary symptoms observed with daily doses of 1-50 mg of rifalazil.

公开(公告)号：EP1139755A4

公开(公告)日：2003-01-02

申请号：EP99968906

申请日：1999-12-16

Applicant: KANEKA CORP

Inventor： ROSE LYNN M ,  PORUBEK DAVID J ,  MONTGOMERY ALAN B

IPC: C07D498/18 ,  A61K9/02 ,  A61K9/14 ,  A61K9/20 ,  A61K9/50 ,  A61K9/52 ,  A61K31/00 ,  A61K31/133 ,  A61K31/42 ,  A61K31/4409 ,  A61K31/4965 ,  A61K31/538 ,  A61K31/5383 ,  A61K31/70 ,  A61K31/7036 ,  A61K31/7048 ,  A61K31/7052 ,  A61K38/00 ,  A61P1/04 ,  A61P11/00 ,  A61P31/04 ,  A61P31/06 ,  A61P31/18 ,  A01N43/40 ,  A61K31/44

CPC classification number: A61K31/538 ,  A61K31/00 ,  A61K31/70 ,  C10M101/025 ,  C10M103/06 ,  C10M105/14 ,  C10M105/24 ,  C10M107/34 ,  C10M107/36 ,  C10M111/00 ,  C10M2201/0603 ,  C10M2201/0613 ,  C10M2201/0623 ,  C10M2201/0653 ,  C10M2201/0663 ,  C10M2201/0803 ,  C10M2201/0853 ,  C10M2201/0863 ,  C10M2201/0873 ,  C10M2201/1006 ,  C10M2201/1023 ,  C10M2201/1033 ,  C10M2201/1053 ,  C10M2201/123 ,  C10M2205/143 ,  C10M2205/163 ,  C10M2205/173 ,  C10M2205/183 ,  C10M2207/0225 ,  C10M2207/1203 ,  C10M2207/1213 ,  C10M2207/1253 ,  C10M2207/163 ,  C10M2207/183 ,  C10M2207/203 ,  C10M2207/243 ,  C10M2209/1033 ,  C10M2209/1045 ,  C10M2209/1055 ,  C10M2209/1065 ,  C10M2209/1075 ,  C10M2209/1085 ,  C10M2209/1095 ,  C10M2209/123 ,  Y10S514/924 ,  Y10S514/931 ,  A61K2300/00

Abstract: A method for treatment of bacterial infections with rifalazil administered once-weekly, or twice-weekly. A method for treatment of tuberculosis caused by Mycobacterium tuberculosis, infections caused by Mycobacterium avium complex, infections caused by Chlamydia pneumoniae and infections caused by Helicobacter pylori by administering to a patient suffering from the bacterial infection 1-100 mg of rifalazil once or twice a week. In this dose regimen, the treatment is fast, efficacious and eliminates undesirable secondary symptoms observed with daily doses of 1-50 mg of rifalazil.

Abstract translation: 给药每周一次，或每周两次一种用于治疗拉齐细菌感染的方法。 一种用于治疗肺结核的方法由结核分枝杆菌引起的，鸟分枝杆菌感染通过给予从细菌感染1-100毫克的利福拉齐的患者，每周一次或两次通过肺炎衣原体和由幽门螺杆菌引起的感染引起的复杂的，感染引起的 ， 在此剂量，方案中的治疗方法是快速，有效和不期望的消除继发症状观察-与每天服用1-50毫克的利福拉齐。

公开(公告)号：ES2264281T3

公开(公告)日：2006-12-16

申请号：ES99968906

申请日：1999-12-16

Applicant: KANEKA CORP

Inventor： ROSE LYNN M ,  PORUBEK DAVID J ,  MONTGOMERY ALAN B

IPC: C07D498/18 ,  A61K9/02 ,  A61K9/14 ,  A61K9/20 ,  A61K9/50 ,  A61K9/52 ,  A61K31/00 ,  A61K31/133 ,  A61K31/42 ,  A61K31/4409 ,  A61K31/4965 ,  A61K31/538 ,  A61K31/5383 ,  A61K31/70 ,  A61K31/7036 ,  A61K31/7048 ,  A61K31/7052 ,  A61K38/00 ,  A61P1/04 ,  A61P11/00 ,  A61P31/04 ,  A61P31/06 ,  A61P31/18 ,  A01N43/40 ,  A61K31/44

Abstract: Uso del Rifalazil para la producción de un medicamento para el tratamiento de infecciones bacterianas en un humano mediante la administración semanal o dos veces por semana en una dosis de 1 a 100 mg., en caso que la infección bacteriana sea causada por el Chlamydia pneumoniae o Helicobacter pylori.

公开(公告)号：PT1139755E

公开(公告)日：2006-08-31

申请号：PT99968906

申请日：1999-12-16

Applicant: KANEKA CORP

Inventor： ROSE LYNN M ,  PORUBEK DAVID J ,  MONTGOMERY ALAN B

IPC: C07D498/18 ,  A61K9/02 ,  A61K9/14 ,  A61K9/20 ,  A61K9/50 ,  A61K9/52 ,  A61K31/00 ,  A61K31/133 ,  A61K31/42 ,  A61K31/4409 ,  A61K31/4965 ,  A61K31/538 ,  A61K31/5383 ,  A61K31/70 ,  A61K31/7036 ,  A61K31/7048 ,  A61K31/7052 ,  A61K38/00 ,  A61P1/04 ,  A61P11/00 ,  A61P31/04 ,  A61P31/06 ,  A61P31/18 ,  A61K31/5375

公开(公告)号：DK1139755T3

公开(公告)日：2006-08-21

申请号：DK99968906

申请日：1999-12-16

Applicant: KANEKA CORP

Inventor： ROSE LYNN M ,  PORUBEK DAVID J ,  MONTGOMERY ALAN B

IPC: A01N43/40 ,  C07D498/18 ,  A61K9/02 ,  A61K9/14 ,  A61K9/20 ,  A61K9/50 ,  A61K9/52 ,  A61K31/00 ,  A61K31/133 ,  A61K31/42 ,  A61K31/44 ,  A61K31/4409 ,  A61K31/4965 ,  A61K31/538 ,  A61K31/5383 ,  A61K31/70 ,  A61K31/7036 ,  A61K31/7048 ,  A61K31/7052 ,  A61K38/00 ,  A61P1/04 ,  A61P11/00 ,  A61P31/04 ,  A61P31/06 ,  A61P31/18

Abstract: A method for treatment of bacterial infections with rifalazil administered once-weekly, or twice-weekly. A method for treatment of tuberculosis caused by Mycobacterium tuberculosis, infections caused by Mycobacterium avium complex, infections caused by Chlamydia pneumoniae and infections caused by Helicobacter pylori by administering to a patient suffering from the bacterial infection 1-100 mg of rifalazil once or twice a week. In this dose regimen, the treatment is fast, efficacious and eliminates undesirable secondary symptoms observed with daily doses of 1-50 mg of rifalazil.