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公开(公告)号：EP2857000A4
公开(公告)日：2015-11-11
申请号：EP13796574
申请日：2013-05-29
Applicant: KAO CORP
Inventor： ORITA MASANORI , NAGASAWA HIDEHIRO
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公开(公告)号：JP2010265268A
公开(公告)日：2010-11-25
申请号：JP2010112384
申请日：2010-05-14
Inventor： NAGASAWA HIDEHIRO
Abstract: PROBLEM TO BE SOLVED: To provide a composition for skin care which can be produced by a simple process, is excellent in stability and can be easily used, has a small content of surfactants, and contains ceramides-containing oily particles.
SOLUTION: The composition for skin care includes an aqueous phase and oily particles dispersed in the aqueous phase. The viscosity of the composition is 1,000-100,000 mPa s at room temperature. In the composition, the oily particles are 0.1-2 mm in average size, contain 15-60 mass% of ceramides, and are contained at 0.5-15 mass%; and the aqueous phase contains 0.1-1.0 mass% of a polymer. A method for producing the composition for skin care use is also provided, comprising the following process: a dissolved oily phase is added from above the aqueous phase to the aqueous phase heated to 50-90°C, or the aqueous phase heated to 50-90°C is added from above the oily phase to the dissolved oily phase; thereafter, a mixture of the aqueous phase and the oily phase is stirred; while the stirring, the mixture is cooled to room temperature to obtain the oily particles.
COPYRIGHT: (C)2011,JPO&INPITAbstract translation: 要解决的问题：为了提供可以通过简单的方法制备的护肤组合物，其稳定性优异并且易于使用，具有少量的表面活性剂，并且含有含有神经酰胺的油性颗粒。 解决方案：用于皮肤护理的组合物包括分散在水相中的水相和油性颗粒。 组合物的粘度在室温下为1000-100,000mPa·s。 在组合物中，油性颗粒的平均尺寸为0.1-2mm，含有15-60质量％的神经酰胺，并且含有0.5-15质量％ 水相含有0.1〜1.0质量％的聚合物。 还提供了一种用于生产用于皮肤护理用途的组合物的方法，包括以下方法：从水相以上加入到50-90℃的水相中加入溶解的油相，或将水相加热至50- 从油相上方向溶解的油相中加入90℃; 然后搅拌水相和油相的混合物; 同时搅拌，将混合物冷却至室温，得到油状颗粒。 版权所有（C）2011，JPO＆INPIT
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公开(公告)号：JP2004277305A
公开(公告)日：2004-10-07
申请号：JP2003068513
申请日：2003-03-13
Inventor： NAGASAWA HIDEHIRO
Abstract: PROBLEM TO BE SOLVED: To provide an aqueous cosmetic which inhibits the recrystallization of paraben.
SOLUTION: This aqueous cosmetic comprises methyl p-hydroxybenzoate and/or ethyl p-hydroxybenzoate, polyethylene glycol having a weight-average mol.wt. of 1,000 to 1,000,000, and a water-containing aqueous medium, wherein the content of the aqueous medium is ≥80 wt.% and the weight ratio of the content of the polyethylene glycol to the total content of the p-hydroxybenzoate and/or ethyl p-hydroxybenzoate is 0.005 to 0.15.
COPYRIGHT: (C)2005,JPO&NCIPIAbstract translation: 待解决的问题：提供抑制对羟基苯甲酸酯重结晶的含水化妆品。 解决方案：该水性化妆品包括对羟基苯甲酸甲酯和/或对羟基苯甲酸乙酯，重均分子量为重量的聚乙二醇。 为1,000〜1,000,000，以及含水水性介质，其中，所述含水介质的含量为≥80重量％，聚乙二醇的含量与对羟基苯甲酸酯和/或乙基的总含量的重量比 对羟基苯甲酸酯为0.005〜0.15。 版权所有（C）2005，JPO＆NCIPI
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公开(公告)号：JP2014108953A
公开(公告)日：2014-06-12
申请号：JP2012264801
申请日：2012-12-03
Inventor： KAMIYAMA CHIHIRO , NAGASAWA HIDEHIRO
IPC: A61K8/41 , A61K8/06 , A61K8/25 , A61K8/34 , A61K8/37 , A61K8/40 , A61K8/42 , A61K8/44 , A61K8/46 , A61Q19/00
CPC classification number: A61K8/442 , A61K8/025 , A61K8/0279 , A61K8/0295 , A61K8/06 , A61K8/25 , A61K8/342 , A61K8/375 , A61K2800/412 , A61Q19/00
Abstract: PROBLEM TO BE SOLVED: To provide an emulsified cosmetic forming a film of a lamellar α-gel structure on a skin surface and maintaining high moisture retention effect and non-sticky condition.SOLUTION: The emulsified cosmetic contains the following components (A), (B), (C), (D) and (E): (A) 0.01 to 10 mass% of one kind or two or more kinds of the compounds selected from among sphingosine salts and ionic surfactants, (B) one kind or two or more kinds of the compounds selected from among di-straight chain fatty acid glycerin esters and di-straight chain fatty acid sorbitan esters, (C) one kind or two or more kinds of the compounds selected from among compounds represented by the general formula (3), alcohols having a carbon number of 12 to 22, mono-fatty acid glycerin esters having a carbon number of 12 to 22, monoalkyl glyceryl ethers having a carbon number of 12 to 22 and mono-fatty acid sorbitan esters having a carbon number of 12 to 22, (D) 0.01 to 30 mass% of a powder having an average grain diameter of 0.1 to 30 μm, and (E) water.
Abstract translation: 要解决的问题：提供在皮肤表面形成层状α-凝胶结构膜的乳化化妆品，并保持高保湿效果和不粘性状态。溶解性：乳化化妆品含有以下成分（A），（ B），（C），（D）和（E）：（A）0.01〜10质量％的选自鞘氨醇盐和离子性表面活性剂的一种或两种以上的化合物，（B） 或更多种选自二 - 直链脂肪酸甘油酯和二 - 直链脂肪酸脱水山梨醇酯的化合物，（C）一种或两种以上选自以下通式的化合物（ 3），碳数为12〜22的醇，碳数为12〜22的单脂肪酸甘油酯，碳数为12〜22的单烷基甘油醚和碳数为1的单脂肪酸脱水山梨糖醇酯 为12〜22，（D）为0.01〜30质量％ 年龄粒径为0.1〜30μm，（E）为水。
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公开(公告)号：JP2007161680A
公开(公告)日：2007-06-28
申请号：JP2005362676
申请日：2005-12-16
Inventor： NISHISAKA TAKAHIRO , NAGASAWA HIDEHIRO
Abstract: PROBLEM TO BE SOLVED: To provide a gel cosmetic which has high viscosity, little gives slimy touch or slippery touch, when used, and gives an excellent sense of use.
SOLUTION: This gel-like cosmetic comprises (A) a cationic group-containing copolymer obtained by radically polymerizing a cationic vinyl monomer, a hydrophilic nonionic group-containing vinyl monomer selected from N,N-dimethyl (meth)acrylamide and N,N-diethyl (meth)acrylamide, and a cross-linkable vinyl monomer having at least two vinyl groups in the molecule as essential constituting monomers, (B) silica, and water in a component (A) : (B) mass ratio of 10:1 to 1:10, and has viscosity of 3,000 to 20,000 mPa s at 25°C.
COPYRIGHT: (C)2007,JPO&INPITAbstract translation: 要解决的问题：提供一种具有高粘度的凝胶化妆品，当使用时很少产生粘糊糊的触感或滑溜感，并且具有优异的使用感。 解决方案：该凝胶状化妆品包含（A）通过使阳离子乙烯基单体自由基聚合而得到的含阳离子基团的共聚物，选自N，N-二甲基（甲基）丙烯酰胺和N （甲基）丙烯酰胺，和分子中具有至少两个乙烯基的可交联乙烯基单体作为必需构成单体，（B）二氧化硅和（A）成分中的水：（B） 10：1〜1:10，25℃下的粘度为3000〜20,000mPa·s。 版权所有（C）2007，JPO＆INPIT
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Patent Agency Ranking
公开(公告)号：JP2005053866A
公开(公告)日：2005-03-03
申请号：JP2003288303
申请日：2003-08-06
Inventor： NAGASAWA HIDEHIRO , KATO KYOICHI
Abstract: PROBLEM TO BE SOLVED: To prepare a cosmetic not requiring an action to break particles on a hand before applying it to skin, free from the remains of capsule coating films of particles when applied, familiar to the skin and having beautiful appearance and refreshing feeling.
SOLUTION: In this cosmetic, the particles having 0.5-5 mm average particle diameter are dispersed in an aqueous medium having ≥500 mPa s viscosity at 25°C and these particles are disintegrated when discharged from a container and average particle diameter of disintegrated particles after discharge is 50-400 μm and the disintegrated particles having ≤400 μm diameters occupy 70 vol% based on total particles.
COPYRIGHT: (C)2005,JPO&NCIPIAbstract translation: 要解决的问题：为了制备在施用于皮肤之前不需要将手上的颗粒破碎的化妆品的化妆品，当被涂覆时，没有颗粒的胶囊涂膜的残留物，熟悉皮肤并且具有美丽的外观和 清爽的感觉 解决方案：在该化妆品中，将平均粒径为0.5-5mm的颗粒分散在25℃下具有≥500mPa·s粘度的水性介质中，这些颗粒在从容器中排出时分解，平均粒径 放电后的崩解颗粒为50-400μm，直径≤400μm的崩解颗粒占总颗粒的70vol％。 版权所有（C）2005，JPO＆NCIPI
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公开(公告)号：JP2003171269A
公开(公告)日：2003-06-17
申请号：JP2001376412
申请日：2001-12-10
Applicant: KAO CORP
Inventor： YAMAMOTO YUMIKO , TANAHASHI MASANORI , NAGASAWA HIDEHIRO , YAMAMOTO TOMOYUKI
IPC: A61K9/10 , A61K8/00 , A61K8/19 , A61K8/30 , A61K8/36 , A61K8/41 , A61K8/42 , A61K8/68 , A61K31/133 , A61K31/164 , A61K31/194 , A61K31/198 , A61K33/42 , A61P17/16 , A61P43/00 , A61Q19/00 , A61K7/00 , A61K7/48
Abstract: PROBLEM TO BE SOLVED: To provide a skin care preparation resistant to the separation and precipitation of ceramides without using a surfactant, a phospholipid, etc., having excellent storage stability and easily giving a transparent to turbid appearance by the adjustment of the components. SOLUTION: The skin care preparation is an emulsion free from acrylic acid polymer or phospholipid and containing (A) a sphingosine expressed by general formula (1) (R 1 is a (substituted) hydrocarbon group; R 2 and R 3 are each OH or the like; Y is methylene, methine, oxygen or the like; X 1 , X 2 and X 3 are each H, OH or the like; X 4 is H or the like; R is H or amidino; and (a) is 2 or 3), (B) an inorganic acid or a ≤5C organic acid and (C) a ceramide expressed by general formula (2) (R 7 is a (substituted) alkyl; Z is methylene, methine, oxygen or the like; R 8 and R 9 are each H, OH or the like; X 4 , X 5 , X 6 and X 7 are each H, OH or the like; R 10 and R 11 are each a substituent) at an ((A)+(B))/(C) weight ratio of ≥0.0001. COPYRIGHT: (C)2003,JPO
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公开(公告)号：JP2014108954A
公开(公告)日：2014-06-12
申请号：JP2012264802
申请日：2012-12-03
Inventor： KAMIYAMA CHIHIRO , NAGASAWA HIDEHIRO
Abstract: PROBLEM TO BE SOLVED: To provide an emulsified cosmetic forming a film of a lamellar α-gel structure on a skin surface and maintaining high moisture retention effect and non-sticky condition.SOLUTION: The emulsified cosmetic contains (A) a polyglycerol mono-fatty acid ester, (B) a C10 to 22 higher alcohol, (C) a compound represented by the formula (1), (D) an anionic surfactant, (E) a powder having an average grain diameter of 0.1 to 30 μm and (F) water each in a specific amount. (In formula, Rrepresents a C4 to 30 hydrocarbon group which may have a substituent or represents H; Z represents a methylene group, a methine group or O; X, Xand Xrepresent H, an OH group or an acetoxy group, and Xrepresents an acetyl group or a glyceryl group; Rand Rrepresent H, an OH group, a hydroxymethyl group or an acetoxymethyl group; Rrepresents a C5 to 60 hydrocarbon group which may have an ether bond, an ester bond or an amide bond in the main chain; Rrepresents H or a C1 to 30 hydrocarbon group which may have a substituent; and the dashed line part may be an unsaturated bond.)
Abstract translation: 要解决的问题：提供在皮肤表面形成层状α-凝胶结构膜的乳化化妆品，并保持高保湿效果和不粘性状态。溶解性：乳化化妆品含有（A）聚甘油单脂肪 酸性酯，（B）C10〜22高级醇，（C）式（1）表示的化合物，（D）阴离子表面活性剂，（E）平均粒径为0.1〜30μm的粉末和（ F）水分别为特定量。 （式中，R表示可以具有取代基或表示H的C 4〜30烃基; Z表示亚甲基，次甲基或O; X，X和X表示H，OH基或乙酰氧基，X表示乙酰基 基团或甘油基;兰德Rrepresent H，OH基，羟甲基或乙酰氧基甲基; R表示在主链中可具有醚键，酯键或酰胺键的C5至60烃基; R代表H 或可以具有取代基的C1〜30烃基;虚线部分可以是不饱和键。）
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公开(公告)号：JP2006312622A
公开(公告)日：2006-11-16
申请号：JP2006103265
申请日：2006-04-04
Inventor： NAGASAWA HIDEHIRO
Abstract: PROBLEM TO BE SOLVED: To provide an oil-in-water type emulsion having excellent sense of use and preservation stability by formulating ceramides without crystallizing the ceramides; and to provide a method for producing the oil-in-water type emulsion by which the ceramides can be stably formulated without crystallizing the ceramides.
SOLUTION: The oil-in-water type emulsion is produced by formulating (A) a 10-30C carboxylic acid and/or a salt thereof, (B) a base, (C) the ceramides, (D) water and (E) a surfactant (except the surfactant derived from the component (A)) while regulating the ratio (mass ratio) of the formulated components (E) to (C) so as to be 0 or more and less than 2.
COPYRIGHT: (C)2007,JPO&INPITAbstract translation: 待解决的问题：提供一种水溶液型乳液，其具有优异的使用感和保存稳定性，通过配制神经酰胺而不使神经酰胺结晶; 并且提供一种生产水包油型乳液的方法，通过该方法可以稳定地配制神经酰胺，而不使神经酰胺结晶。 水包油型乳液通过配制（A）10-30℃羧酸和/或其盐，（B）碱，（C）神经酰胺，（D）水和 （E）表示物（除了组分（A）的表面活性剂）），同时将配制的组分（E）与（C）的比例（质量比）调节至0以上且小于2.
版权所有（C）2007，JPO＆INPIT
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公开(公告)号：JP2006290751A
公开(公告)日：2006-10-26
申请号：JP2005110270
申请日：2005-04-06
Inventor： NAGASAWA HIDEHIRO
Abstract: PROBLEM TO BE SOLVED: To obtain an oil-in-water type emulsion that is formulated with a ceramide without crystallization and has an excellent sense of use and storage stability and to provide a method for producing an oil-in-water type emulsion that is stably formulated with a ceramide without crystallization. SOLUTION: The oil-in-water type emulsion is obtained by formulating (A) a carboxylic acid having 10-30 total carbon atoms and/or its salt with (B) a base, (C) a ceramide, (D) water and (E) a surfactant (a surfactant selected from the component (A) is omitted) in which the formulation ratio (mass ratio) of the component (E)/the component (C) is ≥2, the formulation ratio (mass ratio) R of the component (E)/the component (A) is 0 COPYRIGHT: (C)2007,JPO&INPIT
Abstract translation: 要解决的问题：获得与神经酰胺配制而不结晶的水包油型乳液，并且具有优异的使用感和储存稳定性，并提供一种生产水包油型的方法 与神经酰胺稳定配制而不结晶的乳液。 水溶性乳液通过配制（A）具有10-30个总碳原子的羧酸和/或其盐与（B）碱，（C）神经酰胺，（D ）和（E）表面活性剂（省略了组分（A）中的表面活性剂），其中组分（E）/组分（C）的配比（质量比）≥2，配制比（ （E）/成分（A）的质量比R为0
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