公开(公告)号：WO2022107006A1

公开(公告)日：2022-05-27

申请号：PCT/IB2021/060631

申请日：2021-11-17

Applicant: KHALIFA UNIVERSITY OF SCIENCE AND TECHNOLOGY

Inventor： ALAZZAM, Anas ,  ALSAFAR, Habiba ,  WAHEED, Waqas ,  SAYLAN, Sueda

IPC: C12Q1/6844 ,  B01L7/00 ,  C12M3/00

Abstract: A device (10) and method for detecting COVID-19 and other pathogens includes a sample compartment (26) contained within an interior of the device and having multiple apertures (32) for releasably receiving one or more test tubes (42) containing a biological sample. A bottom portion (48) of the test tube (42) is contained within the interior (22) of the device (10) and a top portion (46) of the test tube (42) is exposed to atmosphere. The biological sample is lysed using the device (10); the lysed sample is mixed with one or more primers and then amplification (RT-LAMP) is performed using the device (10). A thermally conductive material on or in proximity to the sample compartment (26) can facilitate precise heating of the compartment (26) and sample. A thermally insulative material can be inside the interior of the compartment housing (30). Multiple samples can be tested simultaneously. The results can be interpreted by a color change of the sample. The device (10) is efficient, portable, reliable, and re-usable.