公开(公告)号：WO2011078544A3

公开(公告)日：2011-06-30

申请号：PCT/KR2010/009141

申请日：2010-12-21

Applicant: KOREA BASIC SCIENCE INSTITUTE ,  CHOI, Myoung Choul ,  KIM, Hyun Sik ,  YOO, Jong Shin

Inventor： CHOI, Myoung Choul ,  KIM, Hyun Sik ,  YOO, Jong Shin

IPC: H01J37/30 ,  H01J49/26

Abstract: An ion injector may include: a first electrode comprising a first region allowing ions to pass; and a second electrode disposed to enclose one end of the first electrode. The second electrode may include: a second region aligned with the first region to allow the ions to pass; and a protruding portion extending along the path of the ions passing through the second region. A mass spectrometer may be configured by disposing the ion injector adjacent to a skimmer.

公开(公告)号：WO2013055081A1

公开(公告)日：2013-04-18

申请号：PCT/KR2012/008178

申请日：2012-10-10

Applicant: KOREA BASIC SCIENCE INSTITUTE ,  ASTA CO., LTD.

Inventor： CHOI, Myoung Choul ,  CHOI, Sang Hwan ,  LEE, Se Gyu ,  LEE, Jeong Min ,  KIM, Yang Sun

IPC: H01J49/22

CPC classification number: H01J49/067 ,  H01J49/40

Abstract: An ion regulator for a mass spectrometer may include: a first extraction lens having a first hole through which ions can pass; and a second extraction lens electrically isolated from the first extraction lens and having a second hole which is aligned with the first hole so that the ions passing through the first hole can pass therethrough. The surface of the first hole may be inclined with respect to the moving direction of the ions. Use of the ion regulator will simplify the overall structure of a mass spectrometer and control parameters therefor, and will allow the development of a reliable and efficient compact mass spectrometer.

Abstract translation: 用于质谱仪的离子调节器可以包括：具有离子可以通过的第一孔的第一提取透镜; 以及与所述第一提取透镜电隔离并且具有与所述第一孔对准的第二孔的第二提取透镜，使得穿过所述第一孔的所述离子可以通过。 第一孔的表面可以相对于离子的移动方向倾斜。 离子调节器的使用将简化质谱仪的总体结构并控制其参数，并且将允许开发可靠且高效的紧凑型质谱仪。

公开(公告)号：WO2012074234A2

公开(公告)日：2012-06-07

申请号：PCT/KR2011/008866

申请日：2011-11-21

Applicant: KOREA BASIC SCIENCE INSTITUTE ,  CHOI, Myoung Choul ,  PARK, A Leum ,  KIM, Hyun Sik ,  KIM, Seung Yong ,  YOO, Jong Shin

Inventor： CHOI, Myoung Choul ,  PARK, A Leum ,  KIM, Hyun Sik ,  KIM, Seung Yong ,  YOO, Jong Shin

IPC: G01N27/62 ,  H01J49/26

CPC classification number: H01J49/02 ,  H01J49/0027 ,  H01J49/065 ,  H01J49/38

Abstract: A Fourier transform ion cyclotron resonance mass spectrometer (FT-ICR MS) includes: an ionization source generating ions; a deceleration lens, on which the ions generated by the ionization source and spatially dispersed are incident, selectively decelerating the incident ions so as to decrease the distance between the ions; and an ion cyclotron resonance cell on which the ions passing through the deceleration lens are incident. By preventing dispersing of ions due to mass difference and converging the ions using the deceleration lens, the mass range that can be measured at one time can be extended. Also, measurement sensitivity can be improved since the ions are effectively introduced to the ICR cell.

Abstract translation: 傅里叶变换离子回旋共振质谱仪（FT-ICR MS）包括：产生离子的电离源; 由离子源产生的并且空间分散的离子入射的减速透镜选择性地使入射离子减速以减小离子之间的距离; 以及通过减速透镜的离子入射到其上的离子回旋共振单元。 通过防止由于质量差导致的离子分散和使用减速透镜会聚离子，可以延长一次可以测量的质量范围。 此外，由于离子被有效地引入ICR单元，所以可以提高测量灵敏度。

公开(公告)号：WO2013055085A1

公开(公告)日：2013-04-18

申请号：PCT/KR2012/008183

申请日：2012-10-10

Applicant: KOREA BASIC SCIENCE INSTITUTE

Inventor： CHOI, Myoung Choul ,  CHOI, Sang Hwan ,  LEE, Se Gyu ,  LEE, Jeong Min

IPC: H01L21/265

CPC classification number: H01J49/067 ,  H01J49/0027 ,  H01J49/0054 ,  H01J49/062

Abstract: A lens for electron capture dissociation may include: a first electrode and a second electrode spaced apart from each other and arranged along a first direction; and a third electrode and a fourth electrode spaced apart from each other and arranged along a second direction perpendicular to the first direction. The first electrode and the second electrode may be disposed in a space in which a magnetic field is formed in the first direction and trap electrons. The third electrode and the fourth electrode may be in the form of a flat plate and may apply an electric field to the trapped electrons in the second direction.

Abstract translation: 用于电子捕获解离的透镜可以包括：第一电极和彼此间隔开并沿着第一方向布置的第二电极; 以及与第一方向垂直的第二方向配置的第三电极和第四电极。 第一电极和第二电极可以设置在其中在第一方向上形成磁场并捕获电子的空间中。 第三电极和第四电极可以是平板的形式，并且可以在第二方向上对捕获的电子施加电场。

公开(公告)号：WO2012053799A1

公开(公告)日：2012-04-26

申请号：PCT/KR2011/007740

申请日：2011-10-18

Applicant: KOREA BASIC SCIENCE INSTITUTE ,  CHOI, Myoung Choul ,  KIM, Hyun Sik ,  KIM, Seung Yong

Inventor： CHOI, Myoung Choul ,  KIM, Hyun Sik ,  KIM, Seung Yong

IPC: G01N27/62 ,  H01L21/265 ,  H05H13/00

CPC classification number: H01J49/38

Abstract: A Fourier transform ion cyclotron resonance mass spectrometer (FT-ICR MS) may include: a signal generator generating a sinusoidal, first voltage signal having a DC offset; a voltage amplifier receiving the first voltage signal from the signal generator and generating a second voltage signal by amplifying the first voltage signal; and an ion cyclotron resonance (ICR) trap receiving the second voltage signal and generating an ion cyclotron motion centered on the position determined by the DC offset.

Abstract translation: 傅立叶变换离子回旋共振质谱仪（FT-ICR MS）可以包括：产生具有DC偏移的正弦，第一电压信号的信号发生器; 电压放大器，从信号发生器接收第一电压信号，并通过放大第一电压信号产生第二电压信号; 以及离子回旋共振（ICR）陷阱，其接收第二电压信号并产生以由DC偏移确定的位置为中心的离子回旋加速器运动。

公开(公告)号：WO2011081352A3

公开(公告)日：2011-07-07

申请号：PCT/KR2010/009254

申请日：2010-12-23

Applicant: KOREA BASIC SCIENCE INSTITUTE ,  KANG, Duk Jin ,  CHOI, Myoung Choul ,  YOO, Jong Shin ,  KIM, Hyun Sik

Inventor： KANG, Duk Jin ,  CHOI, Myoung Choul ,  YOO, Jong Shin ,  KIM, Hyun Sik

IPC: G01N27/26 ,  H01J49/04 ,  G01N33/48 ,  G01N33/68

Abstract: An apparatus for electrospray ionization may include: a platform including an inlet port, a first channel connected to the inlet port, a second channel connected to the first channel, and an outlet port connected to the second channel; a nebulizer provided in the first channel and configured to spray inert gas to a sample sprayed into the first channel through the inlet port; and a focusing lens provided in the second channel and configured to focus ions produced from the sprayed sample toward the outlet port.

公开(公告)号：WO2007091754A1

公开(公告)日：2007-08-16

申请号：PCT/KR2006/003618

申请日：2006-09-12

Applicant: KOREA BASIC SCIENCE INSTITUTE ,  KIM, Hyun Sik ,  CHOI, Myoung Choul ,  YOO, Jong Shin

Inventor： KIM, Hyun Sik ,  CHOI, Myoung Choul ,  YOO, Jong Shin

IPC: G01N27/62

CPC classification number: G01N27/62

Abstract: A tandem Fourier transform ion cyclotron resonance mass spectrometer is provided. In the mass spectrometer, the ions selected by a FT-ICR mass analyzer, which can perform an ion selection process and a mass measurement process with a time interval between the processes, are transmitted through an ion guide to a collision cell, which is located a predetermined distance from the FT-ICR mass analyzer, to split into fragment ions. The fragment ions are transmitted to the FT-ICR mass analyzer that measures the mass of the fragment ions. The fragment ions are generated in the collision cell 60 established separately from the FT- ICR mass analyzer 40 according to the mass spectrometer. Accordingly, It can solve various problems (e.g., the radius reduction of cyclotron motion of colliding ions, or the removal of periphery gas after generating the fragment ions) occurred in a tandem mass spectrometer using a conventional tandem-in-time mass analysis method. Also, a high resolution and hith sensitivity measurement can be achieved. Moreover, when a reagent gas instead of a collision gas in the collision cell is injected, the gas phase reaction of the selected ions and the reagent gas can be observed, and the mass of the ions generated in the gas phase reaction can be measured.

Abstract translation: 提供了一种串联傅里叶变换离子回旋共振质谱仪。 在质谱仪中，可以进行离子选择处理的FT-ICR质量分析器选择的离子和在处理之间的时间间隔的质量测量过程通过离子导向器传输到位于 距离FT-ICR质量分析器预定的距离，以分裂为碎片离子。 碎片离子传输到测量碎片离子质量的FT-ICR质量分析仪。 在根据质谱仪与FT-ICR质量分析器40分开设置的碰撞单元60中产生碎片离子。 因此，可以使用常规的串联质量分析方法来解决在串联质谱仪中发生的各种问题（例如，产生碰撞离子的回旋加速器运动的半径减小或产生碎片离子之后的外围气体的去除）。 此外，可以实现高分辨率和高灵敏度测量。 此外，当注入反应气体代替碰撞气体中的碰撞气体时，可以观察到所选择的离子和反应气体的气相反应，并且可以测量在气相反应中产生的离子的质量。

公开(公告)号：EP4002424A1

公开(公告)日：2022-05-25

申请号：EP21208217.6

申请日：2021-11-15

Applicant: Korea Basic Science Institute

Inventor： LEE, Sang Ju ,  CHOI, Myoung Choul ,  CHOI, Chang Min ,  HONG, Aram ,  BAEK, Ji Young

IPC: H01J49/14

Abstract: A mixed gas cluster ion beam generator may include a nozzle chamber to contain a first mixed gas which is a mixed gas that is a mix of a first gas and a second gas, a cluster nozzle to spray gas received from the nozzle chamber in a cluster form, an ionizer to ionize a gas cluster sprayed by the cluster nozzle, and an ion accelerator to emit an ion beam to the outside by accelerating the gas cluster ionized by the ionizer by generating a potential difference to the ionized gas cluster.