公开(公告)号：US20200325520A1

公开(公告)日：2020-10-15

申请号：US16760296

申请日：2018-10-30

Applicant: KOREA RESEARCH INSTITUTE OF STANDARDS AND SCIENCE

Inventor： In Chul YANG ,  Ha Jeong KWON ,  Ji Seon JEONG ,  Young Kyung BAE

IPC: C12Q1/68 ,  C12Q1/6806

Abstract: In order to quantitatively analyze nucleic acids present in a sample or a complex medium, a nucleic acid extraction or purification process is required. However, the yield of nucleic acid extraction and purification is greatly variable depending on the purification principle and the characteristics of kit and sample used. Hence, efficient normalization of nucleic acid extraction and purification yield is a prerequisite for accurate quantitative analysis of nucleic acid based on the original sample. The present invention relates to a quantitative analysis method of a nucleic acid present in a sample or a complex medium without amplification of a target nucleic acid.