公开(公告)号：RU2201240C1

公开(公告)日：2003-03-27

申请号：RU2001130870

申请日：2001-11-16

Applicant: KUZNETSOV IGOR VASIL EVICH

Inventor： VASINA T S ,  KUZNETSOV I V ,  SINADSKAJA I A ,  SHEREMET S P

IPC: A61K35/14 ,  A61K9/50

Abstract: FIELD: medicine, technology of medicinal agents, pharmacy. SUBSTANCE: method involves the following stages: powder-like, dried, non-defibrinated blood of Siberian stag, Manchurian wapiti or sika deer is subjected for microcapsulation by preparing the preliminary soaking 8-10% aqueous solution of the above-indicated powder at temperature 30-35 C followed by addition of accessory material to prepared solution. Then the prepared solution is applied on microgranules made of accessory material in granulator device with fluidized bed and with their simultaneous drying. Then accessory-base material envelope is applied on microgranules surface, dried at temperature 38-40 C up to humidity 2%, not less, and calcium stearate is added in granulator device before unloading. Sugar and/or lactose, and/or glucose, and/or fructose, and/or sorbitol are used as accessory material. Ascorbic acid can be used as supplement that is added to solution of accessory material used in envelope applying. Method ensures to prepare preparations showing the enhanced fitness time and no requiring special storage conditions. EFFECT: improved method of preparing. 5 cl