公开(公告)号：US20220258167A1

公开(公告)日：2022-08-18

申请号：US17528070

申请日：2021-11-16

Applicant: Khalifa University of Science and Technology

Inventor： Anas ALAZZAM ,  Habiba ALSAFAR ,  Waqas WAHEED ,  Sueda SAYLAN

IPC: B01L7/00 ,  C12Q1/70

Abstract: A device and method for detecting COVID-19 and other pathogens includes a sample compartment contained within an interior of the device and having multiple apertures for releasably receiving one or more test tubes containing a biological sample. A bottom portion of the test tube is contained within the interior of the device and a top portion of the test tube is exposed to atmosphere. The biological sample is lysed using the device; the lysed sample is mixed with one or more primers and then amplification (RT-LAMP) is performed using the device. A thermally conductive material on or in proximity to the sample compartment can facilitate precise heating of the compartment and sample. A thermally insulative material can be inside the interior of the housing. Multiple samples can be tested simultaneously. The results can be interpreted by a color change of the sample. The device is efficient, portable, reliable, and re-usable.

公开(公告)号：US20250144636A1

公开(公告)日：2025-05-08

申请号：US18947820

申请日：2024-11-14

Applicant: Khalifa University of Science and Technology

Inventor： Anas ALAZZAM ,  Habiba ALSAFAR ,  Waqas WAHEED ,  Sueda SAYLAN

IPC: B01L7/00 ,  C12Q1/70

Abstract: A device and method for detecting COVID-19 and other pathogens includes a sample compartment contained within an interior of the device and having multiple apertures for releasably receiving one or more test tubes containing a biological sample. A bottom portion of the test tube is contained within the interior of the device and a top portion of the test tube is exposed to atmosphere. The biological sample is lysed using the device; the lysed sample is mixed with one or more primers and then amplification (RT-LAMP) is performed using the device. A thermally conductive material on or in proximity to the sample compartment can facilitate precise heating of the compartment and sample. A thermally insulative material can be inside the interior of the housing. Multiple samples can be tested simultaneously. The results can be interpreted by a color change of the sample. The device is efficient, portable, reliable, and re-usable.

公开(公告)号：US20240125781A1

公开(公告)日：2024-04-18

申请号：US17966051

申请日：2022-10-14

Applicant: Khalifa University of Science and Technology

Inventor： Shadi Wajih HASAN ,  Habiba ALSAFAR ,  Ahmed Fayez YOUSEF ,  Vijay Kumar Shankarayya WADI ,  Lina TIZANI ,  Dana KADADOU

IPC: G01N33/569 ,  B05D7/00 ,  G01N27/12 ,  G01N33/543

CPC classification number: G01N33/56983 ,  B05D7/586 ,  G01N27/125 ,  G01N33/5438

Abstract: In some embodiments, a method includes applying an analyte to a rGO biosensor configured to bind to the analyte; applying a DC voltage to the rGO biosensor, wherein the DC voltage is +0.0008V to +0.005V for a negatively charged analyte; or −0.005V to −0.0008 for a positively charged analyte; and monitoring an electrical signal from the rGO biosensor for a response to the analyte.