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1.发明申请SELECTIVE EXPANSION OF DIFFERENT SUBPOPULATIONS OF T CELLS BY THE ALTERATION OF CELL SURFACING SIGNALS AND SIGNAL RATIO 审中-公开改变细胞表面信号和信号比率选择性扩增不同T细胞亚群
公开(公告)号：WO2017072251A1
公开(公告)日：2017-05-04
申请号：PCT/EP2016/075973
申请日：2016-10-27
Applicant: LIFE TECHNOLOGIES AS
Inventor： ALMAASBAK, Hilde, Kjersti , AARVAK, Tanja , BERNSTROEM, Kerstin , AAMELLEM, Oystein
IPC: C12N5/0783
CPC classification number: C12N5/0636 , C12N2501/51 , C12N2501/515 , C12N2501/599
Abstract: This invention relates, inter alia , to compositions of expanded T cell populations, methods for the expansion of T cell populations and methods for using such populations of cells. In some aspects, the invention relates to compositions and methods for the selective expansion of T cell subpopulations present in mixed T cell populations, as well as T cell subpopulations produced by methods for the invention.
Abstract translation: 本发明尤其涉及扩大T细胞群体的组合物，扩增T细胞群体的方法和使用此类细胞群体的方法。 在一些方面，本发明涉及用于选择性扩增存在于混合T细胞群体中的T细胞亚群以及通过本发明的方法产生的T细胞亚群的组合物和方法。
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2.发明公开
公开(公告)号：EP3368659A1
公开(公告)日：2018-09-05
申请号：EP16788673.8
申请日：2016-10-27
Applicant: Life Technologies AS
Inventor： ALMAASBAK, Hilde, Kjersti , AARVAK, Tanja , BERNSTROEM, Kerstin , AAMELLEM, Oystein
IPC: C12N5/0783
CPC classification number: C12N5/0636 , C12N2501/51 , C12N2501/515 , C12N2501/599
Abstract: This invention relates, inter alia, to compositions of expanded T cell populations, methods for the expansion of T cell populations and methods for using such populations of cells. In some aspects, the invention relates to compositions and methods for the selective expansion of T cell subpopulations present in mixed T cell populations, as well as T cell subpopulations produced by methods for the invention.
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