公开(公告)号：US20160299097A1

公开(公告)日：2016-10-13

申请号：US15184133

申请日：2016-06-16

Applicant: LifeScan Scotland Limited

Inventor： Timothy LLOYD ,  David MCCOLL ,  Antony SMITH ,  Brian GUTHRIE ,  David ELDER ,  Rossano MASSARI ,  Christian FORLANI

IPC: G01N27/327

CPC classification number: G01N27/3273 ,  G01N27/3274 ,  G01N27/3275

Abstract: An analyte meter having a test strip port is configured to transmit an electric signal through a received test strip with a sample. A pair of electrodes apply the electric signal and receive an electrical response from the test strip. A processing unit analyzes the electrical response and uses the response to determine an analyte level of the sample.

Abstract translation: 具有测试条端口的分析物计量器被配置为通过带有样品的接收的测试条来传输电信号。 一对电极施加电信号并从测试条接收电响应。 处理单元分析电响应并使用响应来确定样品的分析物水平。

公开(公告)号：US20180188200A1

公开(公告)日：2018-07-05

申请号：US15881838

申请日：2018-01-29

Applicant: LifeScan Scotland Limited

Inventor： Michael MALECHA ,  Antony SMITH ,  David MCCOLL

IPC: G01N27/327 ,  G06F19/24 ,  G01N27/26

CPC classification number: G01N27/3274 ,  G01N27/26 ,  G01N27/3272 ,  G16B40/00

Abstract: Various embodiments for a method that allow for a more accurate analyte concentration with a biosensor by determining at least one physical characteristic of the sample containing the analyte and deriving a parameter relating to the biosensor to attain accurate glucose concentration.

公开(公告)号：US20150362454A1

公开(公告)日：2015-12-17

申请号：US14835755

申请日：2015-08-26

Applicant: LifeScan Scotland Limited

Inventor： Lynsey WHYTE ,  Scott SLOSS ,  David MCCOLL ,  Neil WHITEHEAD ,  Antony SMITH

IPC: G01N27/327

CPC classification number: G01N27/3272 ,  B01L3/502 ,  B01L2300/0825 ,  G01N27/3274 ,  G01N33/492

Abstract: An analytical test strip for the determination of an analyte (such as glucose and/or hematocrit) in a bodily fluid sample (such as a whole blood sample) includes a first capillary sample-receiving chamber, a second capillary sample-receiving chamber, and a physical barrier island disposed between the first and second capillary sample-receiving chambers. Moreover, the physical island barrier is disposed such that bodily fluid sample flow between the first capillary sample-receiving chamber and the second capillary sample-receiving chamber is prevented during use of the analytical test strip.

Abstract translation: 用于测定体液样品（例如全血样品）中的分析物（例如葡萄糖和/或血细胞比容）的分析测试条包括第一毛细管样品接收室，第二毛细管样品接收室和 设置在第一和第二毛细管样品接收室之间的物理屏障岛。 此外，物理岛屏障设置成在分析测试条的使用期间防止了体液样品在第一毛细管样品接收室和第二毛细管样品接收室之间流动。

公开(公告)号：US20200271614A1

公开(公告)日：2020-08-27

申请号：US16066133

申请日：2016-12-22

Applicant: LifeScan Scotland Limited

Inventor： David ELDER ,  David MCCOLL

IPC: G01N27/327

Abstract: A hand-held test meter for use with an electro-chemical-based analytical test strip in the determination of an analyte in a bodily fluid sample includes a housing; a strip port connector disposed at least partially within the housing and configured to receive an electro-chemical based analytical test strip; a micro-controller disposed in the housing and configured to generate a micro-controller command signal; an electrode bias drive circuit block disposed in the housing and configured to generate a bias drive signal based on the micro-controller command signal, and a dynamic bias drive adjustment circuit block disposed in the housing and configured to receive at least one sensed electrode voltage and to adjust a bias drive signal from the electrode bias drive circuit block based on the sensed electrode voltage to create an adjusted bias drive signal.

公开(公告)号：US20160091451A1

公开(公告)日：2016-03-31

申请号：US14496464

申请日：2014-09-25

Applicant: LifeScan Scotland Limited

Inventor： David MCCOLL ,  Antony SMITH

IPC: G01N27/327

CPC classification number: G01N27/3274 ,  G01N27/3272 ,  G01N27/3273

Abstract: Various embodiments for a method that allow for a more accurate analyte concentration with a biosensor by determining at least one physical characteristic signal representative of the sample containing the analyte and selecting an analyte measurement sampling time based on measured temperature, physical characteristic and estimated analyte values.

Abstract translation: 用于通过确定代表含有分析物的样品的至少一个物理特征信号并基于测量的温度，物理特性和估计的分析物值来选择分析物测量取样时间来允许通过生物传感器更准确地分析物浓度的方法的各种实施方案。

公开(公告)号：US20160091450A1

公开(公告)日：2016-03-31

申请号：US14495916

申请日：2014-09-25

Applicant: LifeScan Scotland Limited

Inventor： David MCCOLL ,  Antony SMITH

IPC: G01N27/327

CPC classification number: G01N27/3274 ,  G01N27/3272 ,  G01N27/3273

Abstract: Various embodiments for a method that allow for a more accurate analyte concentration with a biosensor by determining at least one physical characteristic signal representative of the sample containing the analyte and selecting an analyte measurement sampling time based on measured temperature, physical characteristic and estimated analyte values along with temperature compensations provided for specific parameters used in the test assay.

Abstract translation: 用于通过确定代表含有分析物的样品的至少一个物理特征信号并基于测量的温度，物理特性和估计的分析物值选择分析物测量取样时间的方法的各种实施方案，其允许通过生物传感器获得更准确的分析物浓度 提供了用于测试测定中使用的具体参数的温度补偿。

公开(公告)号：US20180156750A1

公开(公告)日：2018-06-07

申请号：US15883111

申请日：2018-01-30

Applicant: LifeScan Scotland Limited

Inventor： Michael MALECHA ,  Antony SMITH ,  David MCCOLL

IPC: G01N27/327 ,  G06F19/24 ,  G01N27/26

CPC classification number: G01N27/3274 ,  G01N27/26 ,  G01N27/3272 ,  G16B40/00

Abstract: Various embodiments for methods and systems that allow for a more accurate analyte concentration with a biosensor by determining at least one physical characteristic of the sample containing the analyte and deriving one of a batch slope, sampling time, or combinations thereof to attain accurate glucose concentration.

公开(公告)号：US20170038331A1

公开(公告)日：2017-02-09

申请号：US14818345

申请日：2015-08-05

Applicant: LifeScan Scotland Limited

Inventor： Gavin MACFIE ,  David MCCOLL

IPC: G01N27/327

CPC classification number: G01N27/3274 ,  G01N27/3272 ,  G01N27/3273

Abstract: A system and a method for correcting an analyte concentration measurement taken by a test strip is described herein. The test strip includes at least two spaced apart electrodes defining an electrochemical cell or reaction chamber. An initial polarization parameter of the test strip is determined at the time of test strip manufacture and a testing polarization parameter is determined at the time of testing. A resulting correction factor is then determined based on the initial and testing polarization parameters. The correction parameter can be applied to a measured analyte concentration in order to correct the measured analyte concentration.

Abstract translation: 本文描述了用于校正由测试条进行的分析物浓度测量的系统和方法。 测试条包括限定电化学电池或反应室的至少两个间隔开的电极。 在测试条制造时确定测试条的初始极化参数，并且在测试时确定测试偏振参数。 然后基于初始和测试偏振参数确定产生的校正因子。 校正参数可以应用于测量的分析物浓度，以便校正测得的分析物浓度。

公开(公告)号：US20160320328A1

公开(公告)日：2016-11-03

申请号：US15104995

申请日：2014-12-22

Applicant: LIFESCAN SCOTLAND LIMITED

Inventor： Timothy LLOYD ,  David MCCOLL ,  Rossano MASSARI ,  Christian FORLANI

IPC: G01N27/327

CPC classification number: G01N27/3274 ,  G01N27/3273

Abstract: A hand-held test meter for use with an electrochemical-based analytical test strip in the determination of an analyte in a bodily fluid sample includes a housing (110), a micro-controller (112) disposed in the housing, an operating range test strip simulation circuit block (“ORTSSCB” 114) disposed in the housing and a strip port connector (“SPC” 106) configured to operationally receive an electrochemical-based analytical test strip. The ORTSSCB is in electrical communication with the SPC. In addition, the ORTSSCB is configured to simulate an electrochemical-based analytical test strip inserted into the SPC and an operating range of bodily fluid samples applied to such an electrochemical-based analytical test strip by sequentially presenting a plurality of electrical loads. Each of the plurality of electrical loads is configured as a first resistor in series with a parallel configuration of a second resistor and a first capacitor. Moreover, the SPC is configured in electrical communication with the micro-controller.

Abstract translation: 用于测定体液样品中的分析物的基于电化学的分析测试条的手持测试仪包括壳体（110），设置在壳体中的微控制器（112），操作范围测试 设置在壳体中的带状模拟电路块（“ORTSSCB”114）“和配置成可操作地接收基于电化学的分析测试条的条形端口连接器（”SPC“106”）。 ORTSSCB与SPC电气通信。 此外，ORTSSCB被配置为模拟插入到SPC中的基于电化学的分析测试条和通过依次呈现多个电负载而施加到这种基于电化学的分析测试条的体液样品的操作范围。 多个电负载中的每一个被配置为与第二电阻器和第一电容器的并联配置串联的第一电阻器。 此外，SPC被配置为与微控制器电通信。

公开(公告)号：US20150369813A1

公开(公告)日：2015-12-24

申请号：US14312991

申请日：2014-06-24

Applicant: LifeScan Scotland Limited

Inventor： Scott SLOSS ,  Lynsey WHYTE ,  Antony SMITH ,  David MCCOLL

IPC: G01N33/66 ,  G01N27/327 ,  B01L3/00 ,  G01N33/80

CPC classification number: G01N33/66 ,  B01L3/502715 ,  B01L2300/0645 ,  B01L2300/0825 ,  B01L2300/0838 ,  B01L2300/0861 ,  B01L2300/0887 ,  G01N27/3272 ,  G01N27/3275 ,  G01N33/80 ,  Y10T436/144444

Abstract: An analytical test strip for the determination of an analyte (such as glucose) in, or a characteristic of, a bodily fluid sample includes an electrically-insulating base layer, a first patterned spacer layer disposed on the electrically-insulating base layer, a second patterned spacer layer disposed on the first patterned spacer layer; and a top hydrophilic layer disposed on the second patterned spacer layer. In addition, the electrically-insulating base layer, the first and second patterned spacer layers and the top hydrophilic layer define a tiered capillary chamber(s) that has a first tiered capillary chamber portion defined in the first patterned spacer layer and a second tiered capillary chamber portion defined in the second patterned spacer layer. Moreover, the first tiered capillary chamber portion and the second tiered capillary chamber portion are in direct fluidic communication with one another.

Abstract translation: 用于测定体液样品中的分析物（例如葡萄糖）或其特性的分析测试条包括电绝缘基层，设置在电绝缘基层上的第一图案化间隔层，第二 设置在第一图案化间隔层上的图案间隔层; 以及设置在第二图案化间隔层上的顶部亲水层。 此外，电绝缘基底层，第一和第二图案化间隔层和顶部亲水层限定了分层毛细管腔室，其具有限定在第一图案化间隔层中的第一分层毛细管室部分和第二分层毛细管 限定在第二图案化间隔层中的腔室部分。 此外，第一分层毛细管腔室部分和第二分层毛细管腔室部分彼此直接流体连通。