公开(公告)号：US11008628B1

公开(公告)日：2021-05-18

申请号：US14490653

申请日：2014-09-18

Applicant: Labrador Diagnostics LLC

Inventor： Elizabeth A. Holmes ,  Timothy Smith ,  Samartha Anekal ,  James R. Wasson ,  Daniel L. Young ,  Chinmay Pangarkar

IPC: C12Q1/70 ,  G01N33/569 ,  B01L7/00 ,  B01L3/00

Abstract: In one embodiment, a method is provided comprising analyte testing on one or more types of samples.

公开(公告)号：US20210404022A1

公开(公告)日：2021-12-30

申请号：US17319906

申请日：2021-05-13

Applicant: Labrador Diagnostics LLC

Inventor： Elizabeth A. Holmes ,  Timothy Smith ,  Samartha Anekal ,  James R. Wasson ,  Daniel L. Young ,  Chinmay Pangarkar

IPC: C12Q1/70 ,  G01N33/569 ,  B01L7/00 ,  B01L3/00

Abstract: In one embodiment, a method is provided comprising analyte testing on one or more types of samples.

公开(公告)号：US12209290B2

公开(公告)日：2025-01-28

申请号：US17319906

申请日：2021-05-13

Applicant: Labrador Diagnostics LLC

Inventor： Elizabeth A. Holmes ,  Timothy Smith ,  Samartha Anekal ,  James R. Wasson ,  Daniel L. Young ,  Chinmay Pangarkar

IPC: B01L3/00 ,  B01L7/00 ,  C12Q1/70 ,  G01N33/569

Abstract: In one embodiment, a method is provided comprising analyte testing on one or more types of samples.

公开(公告)号：US11644410B2

公开(公告)日：2023-05-09

申请号：US17135437

申请日：2020-12-28

Applicant: Labrador Diagnostics LLC

Inventor： Anthony J. Nugent ,  Daniel L. Young ,  Elizabeth A. Holmes ,  Michael Siegel ,  Ryan Wistort

IPC: G01N21/51 ,  G01N21/03 ,  B04B5/04 ,  G01N21/00 ,  B01L3/02 ,  G01N33/543 ,  H04N23/60 ,  C12Q1/42 ,  C12Q1/48 ,  C12Q1/6809 ,  C12Q1/689 ,  G01N21/59 ,  G01N33/569 ,  G01N33/573 ,  G01N33/74 ,  G01N33/80 ,  G06T3/40 ,  G06T7/00 ,  C12Q1/52 ,  C12Q1/6806 ,  G01N1/40 ,  G01N33/53 ,  G01N33/82 ,  G01N33/92 ,  G01N35/10 ,  G16C20/20 ,  G01N35/00

CPC classification number: G01N21/0303 ,  B01L3/0275 ,  B04B5/0421 ,  C12Q1/42 ,  C12Q1/48 ,  C12Q1/52 ,  C12Q1/6806 ,  C12Q1/689 ,  C12Q1/6809 ,  G01N1/4077 ,  G01N21/00 ,  G01N21/51 ,  G01N21/59 ,  G01N33/5308 ,  G01N33/54326 ,  G01N33/54393 ,  G01N33/56972 ,  G01N33/56983 ,  G01N33/573 ,  G01N33/74 ,  G01N33/743 ,  G01N33/80 ,  G01N33/82 ,  G01N33/92 ,  G01N35/10 ,  G06T3/4084 ,  G06T7/0002 ,  G06T7/0012 ,  H04N23/64 ,  B01L2300/168 ,  C12Q2600/158 ,  G01N2001/4083 ,  G01N2035/00495 ,  G01N2035/1018 ,  G01N2333/575 ,  G01N2333/62 ,  G01N2333/91188 ,  G01N2333/96463 ,  G06T2207/30004 ,  G06T2207/30168 ,  G16C20/20

Abstract: The present invention provides systems, devices, and methods for point-of-care and/or distributed testing services. The methods and devices of the invention are directed toward automatic detection of analytes in a bodily fluid. The components of the device can be modified to allow for more flexible and robust use with the disclosed methods for a variety of medical, laboratory, and other applications. The systems, devices, and methods of the present invention can allow for effective use of samples by improved sample preparation and analysis.

公开(公告)号：US11524299B2

公开(公告)日：2022-12-13

申请号：US16712664

申请日：2019-12-12

Applicant: Labrador Diagnostics LLC

Inventor： Elizabeth A. Holmes ,  Joy Roy ,  John Kent Frankovich ,  Daniel L. Young ,  Timothy Smith ,  Chinmay Pangarkar ,  Samartha Anekal

IPC: G01N35/00 ,  B01L3/00 ,  G01N35/10 ,  B01L3/02 ,  B01L7/00 ,  B01L9/06

Abstract: Systems and methods are provided for sample processing. A device may be provided, capable of receiving the sample, and performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing multiple assays. The device may comprise one or more modules that may be capable of performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing the steps using a small volume of sample.

公开(公告)号：US20220258154A1

公开(公告)日：2022-08-18

申请号：US17514466

申请日：2021-10-29

Applicant: Labrador Diagnostics LLC

Inventor： Xinwei Sam Gong ,  Daniel L. Young ,  William Westrick

IPC: B01L3/00 ,  G01N35/00 ,  G01N21/64 ,  G01N21/27 ,  G01N21/03

Abstract: Devices, methods and systems are provided for reducing the sample volume required for analysis. Inserts placed within a sample container, and substitute sample containers having smaller volume sample chambers are provided. Methods are provided for detection and quantification of target substances in reduced volume samples. Methods include placing a small-volume of sample in a small-volume insert. Methods include diluting a small-volume sample, and placing the diluted sample in a small-volume insert. Methods include reducing the volume of sample, and: increasing illumination; increasing dye concentration or amount; increasing the amount of an enzyme substrate; increasing the amounts, concentration, or labeling of antibodies for detection; increasing optical detector sensitivity; increasing the path length of light passing through the sample; decreasing the separation between sample and detector; altering the wavelength, or polarization, or number of wavelengths, passing through the sample; increasing electronic amplification of electrical signals; altering assay temperature; and other alterations.