公开(公告)号：CA2602360A1

公开(公告)日：1999-07-08

申请号：CA2602360

申请日：1998-12-11

Applicant: MAGNETIC IMAGING TECHNOLOGIES

Inventor： DEATON DANIEL ,  ZOLLINGER DAVID ,  DRIEHUYS BASTIAAN ,  HASSON KENTON CHRISTOPHER ,  LANGHORN ALAN

IPC: F17C13/00 ,  F25J1/00 ,  F25J3/06

公开(公告)号：CA2324269C

公开(公告)日：2007-06-12

申请号：CA2324269

申请日：1999-03-17

Applicant: MAGNETIC IMAGING TECHNOLOGIES

Inventor： HASSON KENTON CHRISTOPHER ,  DRIEHUYS BASTIAAN ,  BOGORAD PAUL LEV

IPC: G01R33/28 ,  A61B5/026 ,  A61B5/0275 ,  A61B5/055 ,  A61K49/18 ,  G01R33/563

Abstract: MR spectroscopy and imaging methods for imaging pulmonary and cardiac vasculature and the cardiac region and evaluating blood flow or circulatory deficits use dissolved phase polarized 129Xe gas and large flip angle excitation pulses. Pulmonary and cardiac vasculature MRI images are obtained by delivering gas to a patient via inhalation such as with a breath-hold delivery-procedure, exciting the dissolved phase gas with a large flip angle pulse, and generating a corresponding image. Preferably, the image is obtained using multi-echo imaging techniques. Blood flow is quantified using low field MR spectroscopy and an RF excitation pulse with a frequency which corresponds to the resonance of the dissolved phase 129Xe.

公开(公告)号：CA2313480C

公开(公告)日：2008-02-05

申请号：CA2313480

申请日：1998-12-11

Applicant: MAGNETIC IMAGING TECHNOLOGIES

Inventor： ZOLLINGER DAVID ,  DEATON DANIEL ,  LANGHORN ALAN ,  DRIEHUYS BASTIAAN ,  HASSON KENTON CHRISTOPHER

IPC: A61K49/00 ,  F25J1/00 ,  A61B5/055 ,  A61K49/18 ,  B01J19/26 ,  F17C13/00 ,  F25J3/02 ,  F25J3/06 ,  G01N24/08 ,  G01R33/28 ,  G02F1/1337

Abstract: Methods of collecting, thawing, and extending the useful polarized life of frozen polarized gases include heating a portion of the flow path and/or directly liquefying the frozen gas during thawing. A polarized noble gas product with an extended polarized life product is also included. Associated apparatus such as an accumulator and heating jacket for collecting, storing, and transporting polarized noble gases include a secondary flow channel which provides heat to a portion of t he collection path during accumulation and during thawing.

公开(公告)号：CA2313480A1

公开(公告)日：1999-07-08

申请号：CA2313480

申请日：1998-12-11

Applicant: MAGNETIC IMAGING TECHNOLOGIES

Inventor： DEATON DANIEL ,  HASSON KENTON CHRISTOPHER ,  LANGHORN ALAN ,  DRIEHUYS BASTIAAN ,  ZOLLINGER DAVID

IPC: A61K49/00 ,  A61B5/055 ,  A61K49/18 ,  B01J19/26 ,  F17C13/00 ,  F25J1/00 ,  F25J3/02 ,  F25J3/06 ,  G01R33/28 ,  G02F1/1337

Abstract: Methods of collecting, thawing, and extending the useful polarized life of frozen polarized gases include heating a portion of the flow path and/or directly liquefying the frozen gas during thawing. A polarized noble gas product with an extended polarized life product is also included. Associated apparatus such as an accumulator and heating jacket for collecting, storing, and transporting polarized noble gases include a secondary flow channel which provides heat to a portion of the collection path during accumulation and during thawing.

公开(公告)号：CA2324269A1

公开(公告)日：1999-09-23

申请号：CA2324269

申请日：1999-03-17

Applicant: MAGNETIC IMAGING TECHNOLOGIES

Inventor： DRIEHUYS BASTIAAN ,  BOGORAD PAUL LEV ,  HASSON KENTON CHRISTOPHER

IPC: A61B5/026 ,  A61B5/0275 ,  A61B5/055 ,  A61K49/18 ,  G01R33/28 ,  G01R33/563

Abstract: MR spectroscopy and imaging methods for imaging pulmonary and cardiac vasculature and the cardiac region and evaluating blood flow or circulatory deficits use dissolved phase polarized 129Xe gas and large flip angle excitation pulses. Pulmonary and cardiac vasculature MRI images are obtained by delivering gas to a patient via inhalation such as with a breath-hold delivery-procedure, exciting the dissolved phase gas with a large flip angle pulse, and generating a corresponding image. Preferably, the image is obtained using multi-echo imaging techniques. Blood flow is quantified using low field MR spectroscopy and an RF excitation pulse with a frequency which corresponds to the resonance of the dissolved phase 129Xe.