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公开(公告)号：WO1993019705A1
公开(公告)日：1993-10-14
申请号：PCT/US1993002998
申请日：1993-03-29
Applicant: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
IPC: A61F07/00
CPC classification number: G10K15/02 , A61B2017/22028 , A61N7/02 , A61N2007/006 , A61N2007/0073 , A61N2007/0078 , A61N2007/0095
Abstract: An ultrasound hyperthermia applicator suitable for medical hyperthermia treatment, and method for using the same, includes two ultrasound sources (14, 16) producing focused ultrasound beams of frequencies f0 and f1. Aiming means direct the two ultrasound beams (20, 22) so that they cross each other confocally at the target. A controller (11) activates the two ultrasound sources so that the target is simultaneously irradiated by the two focused ultrasound beams. The two ultrasound sources provide acoustic energy sufficient to cause significant intermodulation products to be produced at the target due to the interaction of the two ultrasound beams. The intermodulation products are absorbed by the target to enhance heating of the target. In preferred embodiments the ultrasound sources include a pair of signal generators (34, 36) for producing gated ultrasound output signals driving single crystal ultrasound transducers (14, 16). In other embodiments the ultrasound sources include a pair of phased array ultrasound transducers for generating two steerable ultrasound beams. Aiming means are provided for electronically steering and focusing the two ultrasound beams so that they cross each other confocally at the target. Further embodiments employ pluralities of transducers, arrays, or both.
Abstract translation: 适用于医疗高热治疗的超声热疗器及其使用方法包括产生频率为f0和f1的聚焦超声波束的两个超声波源（14,16）。 瞄准是指直接两个超声波束（20,22），使得它们在目标处共同交叉。 控制器（11）激活两个超声源，以使靶被同时被两个聚焦的超声波束照射。 由于两个超声波束的相互作用，两个超声波源提供了足够的声能，从而在目标上产生显着的互调产物。 互调产物被目标吸收，以增强目标的加热。 在优选实施例中，超声源包括一对用于产生驱动单晶超声换能器（14,16）的门控超声输出信号的信号发生器（34,36）。 在其他实施例中，超声源包括一对相控阵超声换能器，用于产生两个可操纵超声波束。 提供了用于电子地转向和聚焦两个超声波束的瞄准装置，使得它们在目标处共同交叉。 另外的实施例采用多个换能器，阵列或两者。
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