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公开(公告)号:NO179480B
公开(公告)日:1996-07-08
申请号:NO902852
申请日:1990-06-27
Applicant: ALZA CORP , MEDTRONIC INC
Inventor: PHIPPS JOSEPH B
IPC: A61N1/30
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公开(公告)号:MX174131B
公开(公告)日:1994-04-22
申请号:MX1812089
申请日:1989-10-27
Applicant: MEDTRONIC INC
Inventor: BRENNEN KENNETH R , UNTEREKER DARREL F , PHIPPS JOSEPH B , CAHALAN PATRICK T
Abstract: An improved iontophoresis electrode employing a current distributing member and a drug reservoir containing an ionic drug. The drug reservoir is applied to the skin of a patient, and includes a charge selective ion permeable membrane adapted to contact the skin, through which the ionic drug is delivered.
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公开(公告)号:NZ231164A
公开(公告)日:1992-02-25
申请号:NZ23116489
申请日:1989-10-26
Applicant: MEDTRONIC INC
Inventor: PHIPPS JOSEPH B , UNTEREKER DARREL F , CAHALAN PATRICK T , BRENNEN KENNETH R
Abstract: An improved iontophoresis electrode employing a current distributing member and a drug reservoir containing an ionic drug. The drug reservoir is applied to the skin of a patient, and includes a charge selective ion permeable membrane adapted to contact the skin, through which the ionic drug is delivered.
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公开(公告)号:CA2001444A1
公开(公告)日:1990-04-28
申请号:CA2001444
申请日:1989-10-25
Applicant: MEDTRONIC INC
Inventor: UNTEREKER DARREL F , PHIPPS JOSEPH B , CAHALAN PATRICK T , BRENNEN KENNETH R
Abstract: An improved iontophoresis electrode employing a current distributing member and a drug reservoir containing an ionic drug. The drug reservoir is applied to the skin of a patient, and includes a charge selective ion permeable membrane adapted to contact the skin, through which the ionic drug is delivered.
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公开(公告)号:AT124871T
公开(公告)日:1995-07-15
申请号:AT91908140
申请日:1991-03-29
Applicant: MEDTRONIC INC
Inventor: JEVNE ALLAN H , HOLMBLAD CAROLANN , PHIPPS JOSEPH B , HOWLAND WARREN W
IPC: A61K9/00 , A61K9/70 , A61K47/32 , A61L15/60 , A61N1/30 , C08L33/02 , C09J133/26 , A61L15/16 , C09J133/14
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公开(公告)号:ES2017187A6
公开(公告)日:1991-01-01
申请号:ES8903650
申请日:1989-10-27
Applicant: MEDTRONIC INC
Inventor: UNTEREKER DARREL F , PHIPPS JOSEPH B , CAHALAN PATRICK T , BRENNEN KENNETH R
Abstract: ELECTRODO DE IONTOFORESIS. UN ELECTRODO DE IONTOFORESIS MEJORADO QUE EMPLEA UN MIEMBRO DE DISTRIBUCION DE CORRIENTE Y UN RECIPIENTE DE DROGA QUE CONTIENE UNA DROGA IONICA. EL RECIPIENTE DE LA DROGA SE APLICA A LA PIEL DE UN PACIENTE E INCLUYE UNA MEMBRANA PERMEABLE A LOS IONES SELECTIVA DE CARGA ADAPTADA PARA ENTRAR EN CONTACTO CON LA PIEL, A TRAVES DE LA CUAL SE ADMINISTRA LA DROGA IONICA.
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公开(公告)号:CA2001446A1
公开(公告)日:1990-04-28
申请号:CA2001446
申请日:1989-10-25
Applicant: MEDTRONIC INC
Inventor: PHIPPS JOSEPH B
IPC: A61N1/30
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公开(公告)号:NO902853D0
公开(公告)日:1990-06-27
申请号:NO902853
申请日:1990-06-27
Applicant: MEDTRONIC INC
Inventor: UNTEREKER DARREL F , PHIPPS JOSEPH B , CAHALAN PATRICK T , BRENNEN KENNETH R
Abstract: An improved iontophoresis electrode employing a current distributing member and a drug reservoir containing an ionic drug. The drug reservoir is applied to the skin of a patient, and includes a charge selective ion permeable membrane adapted to contact the skin, through which the ionic drug is delivered.
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公开(公告)号:CA1267937A
公开(公告)日:1990-04-17
申请号:CA493757
申请日:1985-10-24
Applicant: MEDTRONIC INC
Inventor: PHIPPS JOSEPH B , UNTEREKER DARREL F
Abstract: Improved methods of ionophoretic drug delivery are described. By the intentional selection of drug(s) with specific characteristics, of ionotophoresis device, components or both permits the efficiency of drug delivery is increased. Further described is an improved ion to phoresis drug delivery apparatus or device wherein one or more electrochemically active components are employed or "sacrificed" so as to minimize the hydrolysis of water during drug delivery. Drug delivery is made more efficient and pH changes in the device or adjacent the patient's skin are minimized.
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公开(公告)号:MX170809B
公开(公告)日:1993-09-17
申请号:MX1812189
申请日:1989-10-27
Applicant: MEDTRONIC INC
Inventor: PHIPPS JOSEPH B
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