Patent search ap:("MERCK FROSST CANADA INC") AND inv:"ROY PATRICK" Page 1

1.

发明专利
(METHYLSULFONYL)PHENYL-2-(5H)-FURANONE COMPOUNDS AS COX-2 INHIBITOR 失效

公开(公告)号：JP2001199954A

公开(公告)日：2001-07-24

申请号：JP2000366579

申请日：2000-12-01

Applicant: MERCK FROSST CANADA INC

Inventor： BELLEY MICHEL , GAUTHIER JACQUES Y , ERICH GRIMM , LEBLANC YVES , CHUNG-SING LI , THERIEN MICHEL , BLACK CAMERON , CHEUK-KUN LAU , PETPIBOON PRASIT , ROY PATRICK

IPC: C07D333/06 , A61K31/12 , A61K31/122 , A61K31/34 , A61K31/341 , A61K31/343 , A61K31/38 , A61K31/381 , A61K31/404 , A61K31/4184 , A61K31/4196 , A61K31/425 , A61K31/429 , A61K31/433 , A61K31/435 , A61K31/4355 , A61K31/437 , A61K31/44 , A61K31/4427 , A61K31/443 , A61K31/4433 , A61K31/47 , A61K31/4709 , A61K31/505 , A61K31/506 , A61K31/54 , A61P25/04 , A61P29/00 , A61P43/00 , C07C317/24 , C07D213/64 , C07D307/58 , C07D307/60 , C07D307/62 , C07D307/64 , C07D307/66 , C07D307/68 , C07D307/83 , C07D307/94 , C07D333/26 , C07D405/12 , C07D407/12 , C07D409/12 , C07D417/12 , C07D471/04 , C07D491/04 , C07D491/048 , C07D495/04 , C07D498/04 , C07D513/04

Abstract: PROBLEM TO BE SOLVED: To provide a new compound useful for treating cyclooxygenase-2- mediated diseases. SOLUTION: The compound represented by formula (I), and the medicinal composition for treating cyclooxygenase-2-mediated diseases, such as inflammatory diseases. Concretely, the compound of formula (II) is exemplified.

2.

发明专利
PYRIDOPYRROLIZINE AND PYRIDOINDOLIZINE DERIVATIVES 未知

公开(公告)号：CA2503767C

公开(公告)日：2009-09-22

申请号：CA2503767

申请日：2003-10-28

Applicant: MERCK FROSST CANADA INC

Inventor： LEBLANC YVES , ROY PATRICK , DUFRESNE CLAUDE

IPC: C07D471/14 , A61K31/4375 , A61K31/4745 , A61P11/00 , A61P29/00

Abstract: Pyridopyrrolizine and pyridoindolizine derivatives are prostaglandin recepto r antagonists useful for the treatment of prostaglandin-mediated diseases such as allergic rhinitis, nasal congestion and asthma.

3.

发明专利
(Methylsulfonyl)phenyl-2-(5h)-furanone derivatives and pharmaceutical composition in which the derivatives are comprised 未知

公开(公告)号：CZ295764B6

公开(公告)日：2005-10-12

申请号：CZ110198

申请日：1996-10-09

Applicant: MERCK FROSST CANADA INC

Inventor： BELLEY MICHEL , GAUTHIER JACQUES Y , GRIMM ERICH , LEBLANC YVES , LI CHUNG-SING , THERIEN MICHEL , BLACK CAMERON , LAU CHEUK-KUN , PRASIT PETPIBOON , ROY PATRICK

IPC: C07D333/06 , A61K31/12 , A61K31/122 , A61K31/34 , A61K31/341 , A61K31/343 , A61K31/38 , A61K31/381 , A61K31/404 , A61K31/4184 , A61K31/4196 , A61K31/425 , A61K31/429 , A61K31/433 , A61K31/435 , A61K31/4355 , A61K31/437 , A61K31/44 , A61K31/4427 , A61K31/443 , A61K31/4433 , A61K31/47 , A61K31/4709 , A61K31/505 , A61K31/506 , A61K31/54 , A61P25/04 , A61P29/00 , A61P43/00 , C07C317/24 , C07D213/64 , C07D307/58 , C07D307/60 , C07D307/62 , C07D307/64 , C07D307/66 , C07D307/68 , C07D307/83 , C07D307/94 , C07D333/26 , C07D405/12 , C07D407/12 , C07D409/12 , C07D417/12 , C07D471/04 , C07D491/04 , C07D491/048 , C07D495/04 , C07D498/04 , C07D513/04 , A61K31/365 , A61K31/58

Abstract: The present invention relates to (Methylsulfonyl)phenyl-2-(5h)-furanone derivatives of the general formula I, in which the individual general symbols are as specified in the main Claim, wherein these derivatives are effective inhibitors of cyclooxygenase, exhibit antiphlogistic activity and therefore they can be used for the preparation of a pharmaceutical composition forming a part of the present invention, too and having the above-indicated effect.

4.

发明专利
未知

公开(公告)号：BR0315681A

公开(公告)日：2005-09-06

申请号：BR0315681

申请日：2003-10-28

Applicant: MERCK FROSST CANADA INC

Inventor： LEBLANC YVES , DUFRESNE CLAUDE , ROY PATRICK

IPC: A61K31/4745 , A61P11/00 , A61P29/00 , C07D471/14 , A61K31/4375

Abstract: Pyridopyrrolizine and pyridoindolizine derivatives are prostaglandin receptor antagonists useful for the treatment of prostaglandin-mediated diseases such as allergic rhinitis, nasal congestion and asthma.

5.

发明专利
未知

公开(公告)号：NO20052591A

公开(公告)日：2005-07-29

申请号：NO20052591

申请日：2005-05-27

Applicant: MERCK FROSST CANADA INC

Inventor： LEBLANC YVES , ROY PATRICK , DUFRESNE CLAUDE

IPC: A61K31/4745 , A61P11/00 , A61P29/00 , C07D471/14 , A61K31/4375

CPC classification number: C07D471/14

6.

发明专利
未知

公开(公告)号：DE122005000010I1

公开(公告)日：2005-06-23

申请号：DE122005000010

申请日：1996-10-09

Applicant: MERCK FROSST CANADA INC

Inventor： BELLEY MICHEL , GAUTHIER JACQUES Y , GRIMM ERICH , LEBLANC YVES , LI CHUNG SING , THERIEN MICHEL , BLACK CAMERON , LAU CHEUK KUN , PRASIT PETPIBOON , ROY PATRICK

IPC: C07D333/06 , A61K31/12 , A61K31/122 , A61K31/34 , A61K31/341 , A61K31/343 , A61K31/38 , A61K31/381 , A61K31/404 , A61K31/4184 , A61K31/4196 , A61K31/425 , A61K31/429 , A61K31/433 , A61K31/435 , A61K31/4355 , A61K31/437 , A61K31/44 , A61K31/4427 , A61K31/443 , A61K31/4433 , A61K31/47 , A61K31/4709 , A61K31/505 , A61K31/506 , A61K31/54 , A61P25/04 , A61P29/00 , A61P43/00 , C07C317/24 , C07D213/64 , C07D307/58 , C07D307/60 , C07D307/62 , C07D307/64 , C07D307/66 , C07D307/68 , C07D307/83 , C07D307/94 , C07D333/26 , C07D405/12 , C07D407/12 , C07D409/12 , C07D417/12 , C07D471/04 , C07D491/04 , C07D491/048 , C07D495/04 , C07D498/04 , C07D513/04

Abstract: The invention encompasses the novel compound of formula (I) useful in the treatment of cyclooxygenase-2 mediated diseases. The invention also encompasses certain pharmaceutical compositions for treatment of cyclooxygenase-2 mediated diseases comprising compounds of formula (I).

7.

发明专利
未知

公开(公告)号：NO20052591D0

公开(公告)日：2005-05-27

申请号：NO20052591

申请日：2005-05-27

Applicant: MERCK FROSST CANADA INC

Inventor： LEBLANC YVES , ROY PATRICK , DUFRESNE CLAUDE

IPC: A61K31/4745 , A61P11/00 , A61P29/00 , C07D471/14 , C07D

Abstract: Pyridopyrrolizine and pyridoindolizine derivatives are prostaglandin receptor antagonists useful for the treatment of prostaglandin-mediated diseases such as allergic rhinitis, nasal congestion and asthma.