公开(公告)号：WO1995021576A1

公开(公告)日：1995-08-17

申请号：PCT/US1995001776

申请日：1995-02-08

Applicant: MICROVENA CORPORATION

Inventor： MICROVENA CORPORATION ,  KOTULA, Frank ,  CLAUDE, Timothy

IPC: A61B17/22

CPC classification number: A61B17/320758 ,  A61B2017/00553 ,  A61B2017/22038 ,  A61B2017/22039 ,  A61B2017/320775 ,  A61F2002/30093 ,  A61F2210/0019 ,  A61M25/00

Abstract: The present invention provides a mechanical medical device useful for macerating thrombi or the like. In one embodiment of the invention, the device includes a rotor (50) retained in a distal housing (70) having at least one port (74, 75) for ejecting fluid therethrough. The port or ports in this embodiment are sized and positioned so that the surface area of the ports is not evenly distributed about the circumference of the housing. For example, the housing may include a single port, two or more equiangularly spaced ports of different sizes, or two or more ports of the same size spaced unevenly about the circumference of the housing. When a fluid is ejected through the ports, the housing will tend to deflect toward one side of the vascular channel. In accordance with another embodiment, the device includes a plurality of rotors (50A, 50B, 50C) spaced along a common shaft (10) for rotation therewith. In a third embodiment of the device, fluid directing means (e.g. 240) are provided for directing fluid discharged through a port in the housing back toward the rotor.

Abstract translation: 本发明提供一种用于浸渍血栓等的机械医疗装置。 在本发明的一个实施例中，该装置包括保持在远侧壳体（70）中的转子（50），其具有至少一个用于喷射流体的端口（74,75）。 本实施例中的端口或端口的尺寸和位置使得端口的表面积不均匀分布在壳体的圆周上。 例如，壳体可以包括单个端口，两个或更多个等角度间隔开的不同尺寸的端口，或者两个或更多个相同尺寸的端口围绕壳体的圆周不均匀地间隔开。 当流体通过端口喷射时，壳体将倾向于向血管通道的一侧偏转。 根据另一实施例，该装置包括沿公共轴（10）间隔开以与其一起旋转的多个转子（50A，50B，50C）。 在装置的第三实施例中，提供了流体引导装置（例如240），用于引导通过外壳中的端口排出的流体朝向转子。

公开(公告)号：WO1996001591A1

公开(公告)日：1996-01-25

申请号：PCT/US1995008613

申请日：1995-07-10

Applicant: MICROVENA CORPORATION

Inventor： MICROVENA CORPORATION ,  MAZZOCCHI, Rudy ,  CLAUDE, Timothy ,  SEGERMARK, James

IPC: A61B17/22

CPC classification number: A61F2/013 ,  A61B17/12022 ,  A61B17/12099 ,  A61B17/12109 ,  A61B17/12136 ,  A61B17/12172 ,  A61B17/12177 ,  A61B17/221 ,  A61B2017/00526 ,  A61F2/01 ,  A61F2002/011 ,  A61F2002/016 ,  A61F2230/0006 ,  A61F2230/0067 ,  A61F2230/0069 ,  A61F2230/0078 ,  A61F2230/008 ,  B21F45/008

Abstract: The present invention provides a method of forming a medical device and medical devices which can be formed in accordance with the method. In one embodiment, the method includes the steps of: a) providing a metal fabric formed of a plurality of strands formed of a metal which can be heat treated to substantially set a desired shape; b) deforming the metal fabric to generally conform to a surface of a molding element; c) heat treating the metal fabric in contact with the surface of the molding element to substantially set the shape of the fabric in its deformed state; and d) removing the metal fabric from contact with the molding element. The resulting metal fabric will define a medical device which can be collapsed for passage through a catheter or the like for deployment in a channel of a patient's body. Medical devices made in accordance with this method can have varying structures. In one embodiment, the medical device (250) is carried by a guidewire (260) and has a metal fabric (270) extending between first and second ends (272, 274), one end (274) of the device (250) being adapted to slide along the guidewire (260). The metal fabric (270) has a collapsed configuration in which the ends (272, 274) of the metal fabric (270) are spaced from one another along the guidewire (260) and a preset expanded configuration in which the ends (272, 274) of the metal fabric (270) are positioned closer to one another. The metal fabric (270) will cause the device (250) to elastically substantially resume its preset expanded configuration when released from confinement within a channel in a patient's body.

Abstract translation: 本发明提供一种可以根据该方法形成的医疗装置和医疗装置的形成方法。 在一个实施例中，该方法包括以下步骤：a）提供由多个由金属形成的股线形成的金属织物，该金属纤维可被热处理以基本上设定所需形状; b）使金属织物变形以与模制元件的表面大致相符; c）对与模制元件的表面接触的金属织物进行热处理，以将织物的形状基本上设定在其变形状态; 以及d）去除金属织物与模制元件的接触。 所得到的金属织物将限定医疗装置，其可以被折叠以通过导管等以用于部署在患者身体的通道中。 根据该方法制造的医疗装置可以具有不同的结构。 在一个实施例中，医疗装置（250）由导丝（260）承载，并且具有在第一和第二端（272,274）之间延伸的金属织物（270），装置（250）的一端（274）为 适于沿着导丝（260）滑动。 金属织物（270）具有折叠构造，其中金属织物（270）的端部（272,274）沿着导丝（260）彼此间隔开，并且具有预设的扩展构型，其中端部（272,274） ）的金属织物（270）彼此更靠近。 金属织物（270）将使得装置（250）在从患者身体的通道内的限制释放时基本上恢复其预设的扩张构型。

公开(公告)号：WO1997026939A1

公开(公告)日：1997-07-31

申请号：PCT/US1996000893

申请日：1996-01-24

Applicant: MICROVENA CORPORATION ,  MAZZOCCHI, Rudy

Inventor： MICROVENA CORPORATION

IPC: A61M29/00

CPC classification number: A61F2/013 ,  A61B17/12022 ,  A61B17/12099 ,  A61B17/12109 ,  A61B17/12136 ,  A61B17/12172 ,  A61B17/12177 ,  A61B17/221 ,  A61B2017/00526 ,  A61F2/01 ,  A61F2002/011 ,  A61F2002/016 ,  A61F2230/0006 ,  A61F2230/0067 ,  A61F2230/0069 ,  A61F2230/0078 ,  A61F2230/008 ,  B21F45/008

Abstract: The present invention provides aneurysm occlusion device (60, 160) formed from a resilient metal fabric, and a method for reliably and effectively occluding aneurysms. In accordance with one aspect of the invention, the aneurysm devices include a body portion (80) which is sized to be received within an aneurysm and an anchor (70) which is sized, and may also be preformed into a specific shape to engage the lumen of a vessel having the aneurysm thereon. The aneurysm occlusion device (60) may also include a generally tubular central portion (62) extending between the body portion and the anchor, the central portion being sized and shaped to be received within the neck of the aneurysm. The present invention has particular advantages over prior minimally invasive techniques for occluding aneurysms in that it can both fill the aneurysm and occlude or "stent" the neck of the aneurysm in one step. It also minimizes damage to healthy vessel tissue by localizing contact with the interior of the vessel.

Abstract translation: 本发明提供由弹性金属织物形成的动脉瘤闭塞装置（60,160），以及用于可靠且有效地闭塞动脉瘤的方法。 根据本发明的一个方面，动脉瘤装置包括主体部分（80），其尺寸设置成容纳在动脉瘤内，并且锚固件（70）的尺寸被设计成并且也可以预成形为特定形状以接合 具有动脉瘤的容器的管腔。 动脉瘤闭塞装置（60）还可以包括在主体部分和锚固件之间延伸的大致管状的中心部分（62），中心部分的大小和形状被容纳在动脉瘤的颈部内。 本发明具有优于先前用于闭塞动脉瘤的微创技术的优点，因为它可以在一个步骤中填充动脉瘤并阻塞或“支架”动脉瘤的颈部。 它还通过定位与血管内部的接触来最小化对健康血管组织的损伤。

公开(公告)号：WO1996023441A1

公开(公告)日：1996-08-08

申请号：PCT/US1996001226

申请日：1996-01-26

Applicant: MICROVENA CORPORATION

Inventor： MICROVENA CORPORATION ,  ERICKSON, David, S. ,  MAZZOCCHI, Rudy

IPC: A61B05/00

CPC classification number: A61M25/09 ,  A61M2025/09166 ,  A61M2025/09175

Abstract: An embodiment of the invention provides a guidewire having a coil which comprises at least a distal coil segment (24) and a proximal coil segment (22), one of the coil segments being more radiopaque than at least one of the other coil segments. An elongate wire (14) may extend within the lumen of the coil. In a two segment coil, the distal end of the distal coil segment is attached to the wire (14) and the proximal end of the distal coil segment is attached to the distal end of the proximal coil segment while the proximal end of the proximal coil segment is attached to the wire (14).

Abstract translation: 本发明的一个实施例提供了一种具有线圈的导丝，该线圈至少包括远侧线圈段（24）和近端线圈区段（22），其中一个线圈段比其他线圈段中的至少一个更不透射线。 细长线（14）可以在线圈的内腔内延伸。 在两段线圈中，远侧线圈段的远端附接到线（14），并且远端线圈段的近端附接到近端线圈段的远端，而近端线圈的近端 片段附接到线（14）。

公开(公告)号：WO1992022253A1

公开(公告)日：1992-12-23

申请号：PCT/US1992004787

申请日：1992-06-08

Applicant: MICROVENA CORPORATION

Inventor： MICROVENA CORPORATION ,  KOTULA, Frank ,  CLAUDE, Timothy

IPC: A61B17/22

CPC classification number: A61B17/320758 ,  A61B2017/00553 ,  A61B2017/22038 ,  A61B2017/22039 ,  A61B2017/320775 ,  A61F2002/30093 ,  A61F2210/0019 ,  A61M25/00

Abstract: A medical device to break down thrombus or the like includes an elongated, flexible shaft (10) which may be guided along a vascular path. A rotor (50), or "impeller" is attached to the shaft (10) and is retained in a rotor housing (70). The housing (70) has ports (74) to eject fluid drawn by the rotor (50). A driving source (100) is provided to rapidly rotate the shaft (10) and the rotor.

Abstract translation: 用于分解血栓等的医疗装置包括可以沿着血管路径引导的细长的柔性轴（10）。 转子（50）或“叶轮”附接到轴（10）并保持在转子壳体（70）中。 壳体（70）具有用于喷射由转子（50）抽出的流体的端口（74）。 提供驱动源（100）以使轴（10）和转子快速旋转。