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公开(公告)号:DE69720509T2
公开(公告)日:2003-11-13
申请号:DE69720509
申请日:1997-11-18
Applicant: MID AMERICA COMMERCIALIZATION , BASF AG
Inventor: ANNEN ULRICH , DELINE E , FOLAND D , KLOTTER A , MUELLER JOSEF , MUELLER MICHAEL , MUENDINGER KLAUS , PHILLIPPI A , RULAND ALFRED , SCHAEFER WOLFGANG , SCHUERMANN GREGOR , WIDDER RUDI , ZIELSKE G
IPC: C07D295/14 , C07D265/12 , C07D291/00 , C07D295/15 , C11D3/39 , C07D295/12 , C07D211/26 , C07D211/34
Abstract: A process for the preparation of a compound having the structure of Formula (I) wherein A, R1, R2, R3, Y and Z are as defined in the disclosure. The process includes reacting a heterocyclic amine with a monoaldehyde or a dialdehyde in a pH range of from about 8 to 14 and then quaternizing the so-reacted heterocyclic amine with an alkylating agent at a pH of not less than about 2. The use of a pH control substantially prevents formation of an undesirable protonated intermediate.
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公开(公告)号:DE69727711D1
公开(公告)日:2004-03-25
申请号:DE69727711
申请日:1997-11-18
Inventor: ANNEN ULRICH , DELINE E , KLOTTER A , MUELLER MICHAEL , MUNDINGER KLAUS , PERKINS A , PHILLIPPI A , SCHOLTISSEK MARTIN , SCHOENHERR MICHAEL , SMITH L , ZIELSKE G
IPC: C07D295/14 , C07D295/15 , C11D3/39 , C11D3/395 , D06L3/02 , D06L4/12 , C07D265/30 , C07D295/12 , C07D211/26 , C07D211/34 , C01B3/00 , C11D7/38
Abstract: A substantially solid composition, the composition having therein a compound with the structure of Formula (I) wherein A, R1, R2, R3, Y and Z are as defined in the disclosure.
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公开(公告)号:DE69720509D1
公开(公告)日:2003-05-08
申请号:DE69720509
申请日:1997-11-18
Inventor: ANNEN ULRICH , DELINE E , FOLAND D , KLOTTER A , MUELLER JOSEF , MUELLER MICHAEL , MUENDINGER KLAUS , PHILLIPPI A , RULAND ALFRED , SCHAEFER WOLFGANG , SCHUERMANN GREGOR , WIDDER RUDI , ZIELSKE G
IPC: C07D295/14 , C07D265/12 , C07D291/00 , C07D295/15 , C11D3/39 , C07D295/12 , C07D211/26 , C07D211/34
Abstract: A process for the preparation of a compound having the structure of Formula (I) wherein A, R1, R2, R3, Y and Z are as defined in the disclosure. The process includes reacting a heterocyclic amine with a monoaldehyde or a dialdehyde in a pH range of from about 8 to 14 and then quaternizing the so-reacted heterocyclic amine with an alkylating agent at a pH of not less than about 2. The use of a pH control substantially prevents formation of an undesirable protonated intermediate.
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公开(公告)号:DE69727711T2
公开(公告)日:2004-07-15
申请号:DE69727711
申请日:1997-11-18
Inventor: ANNEN ULRICH , DELINE E , KLOTTER A , MUELLER MICHAEL , MUNDINGER KLAUS , PERKINS A , PHILLIPPI A , SCHOLTISSEK MARTIN , SCHOENHERR MICHAEL , SMITH L , ZIELSKE G
IPC: C07D295/14 , C07D295/15 , C11D3/39 , C11D3/395 , D06L3/02 , D06L4/12 , C07D265/30 , C07D295/12 , C07D211/26 , C07D211/34 , C01B3/00 , C11D7/38
Abstract: A substantially solid composition, the composition having therein a compound with the structure of Formula (I) wherein A, R1, R2, R3, Y and Z are as defined in the disclosure.
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