-
公开(公告)号：AT18199T
公开(公告)日：1986-03-15
申请号：AT82109756
申请日：1982-10-22
Applicant: MILES LAB
Inventor： ALBARELLA JAMES PAUL , CARRICO ROBERT JOSEPH , LI THOMAS M
IPC: C07K17/06 , C07C101/72 , C07C123/00
-
公开(公告)号：FI68324B
公开(公告)日：1985-04-30
申请号：FI761148
申请日：1976-04-26
Applicant: MILES LAB
IPC: G01N33/542 , C07D209/48 , C07D237/32 , C07D493/10 , C07D495/04 , C07H19/20 , C07H19/207 , C07H21/00 , C12Q1/00 , G01N31/00 , G01N33/50 , G01N33/532 , G01N33/533 , G01N33/536 , G01N33/543 , G01N33/60
-
公开(公告)号：CH635438A5
公开(公告)日：1983-03-31
申请号：CH497976
申请日：1976-04-21
Applicant: MILES LAB
IPC: G01N33/542 , C07D209/48 , C07D237/32 , C07D493/10 , C07D495/04 , C07H19/20 , C07H19/207 , C07H21/00 , C12Q1/00 , G01N31/00 , G01N33/50 , G01N33/532 , G01N33/533 , G01N33/536 , G01N33/543 , G01N33/60 , G01N33/54
-
公开(公告)号：DK150808C
公开(公告)日：1988-02-15
申请号：DK576281
申请日：1981-12-23
Applicant: MILES LAB
IPC: G01N33/542 , C07D209/48 , C07D237/32 , C07D493/10 , C07D495/04 , C07H19/20 , C07H19/207 , C07H21/00 , C12Q1/00 , G01N31/00 , G01N33/50 , G01N33/532 , G01N33/533 , G01N33/536 , G01N33/543 , G01N33/60 , G01N33/531 , G01N33/537
-
公开(公告)号：FI840616A0
公开(公告)日：1984-02-15
申请号：FI840616
申请日：1984-02-15
Applicant: MILES LAB
IPC: G01N20060101 , G01N33/536 , G01N
-
Patent Agency Ranking
公开(公告)号：DE3060374D1
公开(公告)日：1982-06-24
申请号：DE3060374
申请日：1980-10-15
Applicant: MILES LAB
Inventor： CARRICO ROBERT JOSEPH , NGO THAT TJIEN
IPC: G01N33/532 , A61K39/00 , C07H19/20 , C07H19/207 , C07H21/00 , C07K14/00 , C12N9/04 , G01N33/533 , G01N33/535 , C07G7/00
Abstract: Flavin adenine dinucleotide-labeled conjugates of the formula: wherein Riboflavin-Phos)2 Ribose represents the riboflavin-pyrophosphate-ribose residue in flavin adenine dinucleotide (FAD), -NH)L is a protein or polypeptide (e.g., an immunoglobulin) bound through an amino group thereof, n is an integer from 2 through 10, m is an integer from 1 through 10, and p is on the average from 1 to the number of available amino groups in L. The FAD-labeled conjugates are useful as reagents in specific binding assays (e.g., immunoassays) to determine the conjugated protein or polypeptide, or a specific binding analog or partner thereof, in liquid media.
-
公开(公告)号：DE2924332A1
公开(公告)日：1980-01-03
申请号：DE2924332
申请日：1979-06-15
Applicant: MILES LAB
Inventor： CARRICO ROBERT JOSEPH , JOHNSON RICHARD DON
IPC: C07H19/16 , C07H21/00 , G01N33/535 , G01N33/78 , G01N33/00
-
公开(公告)号：DE2754086A1
公开(公告)日：1978-06-22
申请号：DE2754086
申请日：1977-12-05
Applicant: MILES LAB
IPC: G01N33/536 , G01N33/50 , G01N33/53 , G01N33/532 , G01N33/542 , G01N33/543 , G01N31/14 , G01N33/16
Abstract: A specific binding assay method employing, as a labeling substance, a reversibly binding enzyme modulator for the detection of a ligand in a liquid medium. The method follows conventional specific binding assay techniques of either the homogeneous or heterogeneous type wherein the liquid medium to be assayed is combined with reagent means that includes a labeled conjugate to form a binding reaction system having a bound-species and a free-species of the conjugate. The amount of conjugate resulting in the bound-species or the free-species is a function of the amount of ligand present in the liquid medium assayed. In the present invention, the labeled conjugate comprises a reversibly binding enzyme modulator covalently linked to a binding component of the binding reaction system. The distribution of the conjugate between the bound-species and the free-species is determined by addition of an enzyme whose activity is affected, either decreased or increased, by said modulator and measuring the resulting activity of the enzyme. The enzyme modulator may be a conventional enzyme inhibitor, preferably of the coompetitive type, or an allosteric effector.
-
公开(公告)号：AU1335376A
公开(公告)日：1977-11-03
申请号：AU1335376
申请日：1976-04-27
Applicant: MILES LAB
IPC: G01N33/542 , C07D209/48 , C07D237/32 , C07D493/10 , C07D495/04 , C07H19/20 , C07H19/207 , C07H21/00 , C12Q1/00 , G01N31/00 , G01N33/50 , G01N33/532 , G01N33/533 , G01N33/536 , G01N33/543 , G01N33/60 , G01N33/16
-
公开(公告)号：DE2618511A1
公开(公告)日：1976-11-04
申请号：DE2618511
申请日：1976-04-27
Applicant: MILES LAB
IPC: G01N33/542 , C07D209/48 , C07D237/32 , C07D493/10 , C07D495/04 , C07H19/20 , C07H19/207 , C07H21/00 , C12Q1/00 , G01N31/00 , G01N33/50 , G01N33/532 , G01N33/533 , G01N33/536 , G01N33/543 , G01N33/60 , G01N31/22 , G01N31/14 , G01N33/16
-
-
-
-
-
-
-
-
-
Search Results
41
records
(took 0.022 seconds)
