Abstract:
The present invention provides a unique approach for the diagnosis and management of infections by Chlamydia species, particularly C. pneumoniae. The invention is based, in part, upon the discovery that a combination of agents directed toward the various stages of the chlamydial life cycle is effective in substantially reducing infection. Products comprising combination of antichlamydial agents, novel compositions and pharmaceutical packs are also described.
Abstract:
The present invention provides a unique approach for the diagnosis and management of infections by Chlamydia species, particularly C. pneumoniae. The invention is based, in part, upon the discovery that a combination of agents directed toward the various stages of the chlamydial life cycle is effective in substantially reducing infection. Products comprising combination of antichlamydial agents, novel compositions and pharmaceutical packs are also described.
Abstract:
HIV virus mutants having an alteration which inhibits induction of enhancing antibody to said virus are described. Also described are HIV virus mutants in which an antibody-dependent enhancing domain in gp41 includes amino acid alterations. Also described are HIV vaccines comprising HIV gp160 mutants in which an antibody-dependent enhancing domain in gp41 includes at least one amino acid alteration.