公开(公告)号：WO1996002824A1

公开(公告)日：1996-02-01

申请号：PCT/US1995007834

申请日：1995-06-20

Applicant: MOLECULAR DYNAMICS

Inventor： MOLECULAR DYNAMICS ,  HUETON, Iain ,  VAN GELDER, Ezra

IPC: G01N21/61

CPC classification number: G01N21/6452 ,  G01N27/44721 ,  G01N2021/6417 ,  G01N2201/101

Abstract: A high-speed fluorescence scanner for scanning a sample at equal angles has most of its optical components, including a light beam source (11), a detector (19), filters (18), lenses (17), and reflectors (15-16), in a fixed position (24), removed from the scan head (22). The lightweight scan head contains a single reflector (13) and lens (12) combination which is reciprocated rapidly along one axis to lengthen and shorten a region of the path of a collimated excitation beam (30) and to form a scan line (25-26) on a sample. The fluorescence emission is gathered by the lens (12) of the scan head and directed back, generally along the optical path of the excitation beam, to a detector. Another embodiment places the light source (43), in miniature form, directly on the scan head. The sample may be translated in an axis orthogonal to the scan line to stimulate fluorescent emission from two-dimensional portion of the sample.

Abstract translation: 用于以相等的角度扫描样品的高速荧光扫描器具有其大部分光学部件，包括光束源（11），检测器（19），滤光器（18），透镜（17）和反射器（15- 在固定位置（24）中，从扫描头（22）移除。 轻型扫描头包含单个反射器（13）和透镜（12）组合，其沿着一个轴线快速往复运动，以延长和缩短准直激励光束（30）的路径的区域并形成扫描线（25- 26）。 荧光发射由扫描头的透镜（12）聚集，并且通常沿着激发光束的光路向后指向检测器。 另一实施例将光源（43）以微型形式放置在扫描头上。 样品可以在与扫描线正交的轴上平移以刺激来自样品的二维部分的荧光发射。

公开(公告)号：WO1996012233A1

公开(公告)日：1996-04-25

申请号：PCT/US1995013334

申请日：1995-10-18

Applicant: MOLECULAR DYNAMICS

Inventor： MOLECULAR DYNAMICS ,  CARLSON, Jeffrey, D. ,  FERNANDES, Jorge, M.

IPC: G06F15/00

CPC classification number: G06F8/34 ,  Y10S715/967

Abstract: A method and apparatus for causing a computer (102) to drive one or more external devices is provided (104, 106, 108, 110). A computer (102) executes instructions which cause the computer to display an experiment design region and a set of icons. A user copies the icons into the experiment design region to specify the various phases of an experiment. By setting controls in windows associated with the icons, a user specifies how the general stages of an experiment will be performed, devices used, stored data format, calculations, and report format by constructing an iconic sequence.

Abstract translation: 提供了一种使计算机（102）驱动一个或多个外部设备的方法和装置（104,106,108,110）。 计算机（102）执行使计算机显示实验设计区域和一组图标的指令。 用户将图标复制到实验设计区域中，以指定实验的各个阶段。 通过在与图标相关联的窗口中设置控件，用户通过构建图标序列来指定实验的一般阶段，使用的设备，存储的数据格式，计算和报告格式。