公开(公告)号：DE69834263D1

公开(公告)日：2006-05-24

申请号：DE69834263

申请日：1998-09-24

Applicant: MONASH UNIVERSITY CLAYTON

Inventor： SMALL HENRY ,  SAEZ-VALERO JAVIER ,  SBERNA GIAN

IPC: C12Q1/46 ,  G01N33/573 ,  C12N9/16 ,  C12N9/18 ,  G01N33/68

公开(公告)号：DE60210741D1

公开(公告)日：2006-05-24

申请号：DE60210741

申请日：2002-01-23

Applicant: MONASH UNIVERSITY CLAYTON

Inventor： SMALL HENRY ,  FODERO LISA

IPC: G01N33/68

Abstract: The invention provides a method for the diagnosis of dementia and transmissible spongiform encephalopathies in a subject by detecting the levels of glycoproteins that bind wheat germ agglutinin. The invention also provides a method for diagnosis of dementia and transmissible spongiform encephalopathies in a subject by comparing the levels of glycoproteins that bind wheat germ agglutinin with the glycosylation patterns of biomarkers, acetylcholinesterase and butyrylcholinesterase.