公开(公告)号：US09642956B2

公开(公告)日：2017-05-09

申请号：US13595461

申请日：2012-08-27

Applicant: Matthew D. Landrigan ,  Matthew Swift

Inventor： Matthew D. Landrigan ,  Matthew Swift

IPC: B01L3/00 ,  B01D21/26 ,  A61M1/36 ,  A61M1/02 ,  B01D17/02 ,  B01L9/06

CPC classification number: A61M1/029 ,  A61M1/3693 ,  B01D17/0217 ,  B01D21/262 ,  B01D2221/10 ,  B01L3/50215 ,  B01L9/06 ,  B01L2400/0409 ,  B01L2400/0478 ,  B01L2400/0605 ,  B01L2400/0638

Abstract: A buoy or float can be positioned within a separation container to assist in a physical separation of components of a whole material positioned in the separation container. The buoy can be positioned within the container to move from between and separation a first end and a second end of the container substantially unaffected by a portion of the whole material, including a clotted portion thereof. A first port can be provided near the first end of the container for introduction of the whole material and a second port can be provided near the second end of the container for removal of at least a portion of a separated material.

公开(公告)号：US20120035501A1

公开(公告)日：2012-02-09

申请号：US12849412

申请日：2010-08-03

Applicant: Matthew D. Landrigan ,  James M. McKale

Inventor： Matthew D. Landrigan ,  James M. McKale

IPC: A61B10/00

CPC classification number: A61B10/025 ,  A61B2010/0258

Abstract: A bone marrow aspiration assembly including an outer cannula and an inner cannula. The inner cannula is moved only radially about a longitudinal axis thereof with respect to the outer cannula to selectively align inner openings of only one of distal, intermediate, and proximal opening groups of the inner cannula with outer openings of only one of distal, intermediate, and proximal opening groups of the outer cannula to permit aspiration therethrough.

Abstract translation: 包括外套管和内插管的骨髓抽吸组件。 内套管相对于外套管的纵向轴线径向移动，以便仅选择性地将内套管的远端，中间和近侧开口组中的一个的内部开口与只有远端的，中间的， 和外套管的近端开口组以允许穿过其中。

公开(公告)号：US09078639B2

公开(公告)日：2015-07-14

申请号：US13332799

申请日：2011-12-21

Applicant: Matthew D. Landrigan ,  James M. McKale

Inventor： Matthew D. Landrigan ,  James M. McKale

IPC: A61M25/01 ,  A61B10/02

CPC classification number: A61B10/025 ,  A61B2010/0258

Abstract: A bone marrow aspiration assembly including an outer cannula assembly, an inner cannula assembly, and a flexible seal. The outer cannula assembly includes an outer handle and an outer cannula defining a first passageway and including a plurality of first openings between a first end and a second end of the first passageway. The inner cannula assembly includes an inner handle and an inner cannula defining a second passageway and is configured to be received within the first passageway. The inner cannula includes a plurality of second openings between a first end and a second end of the second passageway. The flexible seal is mounted to the inner handle and positioned such that the seal contacts the outer cannula assembly when the inner cannula assembly is in cooperation with the outer cannula assembly to create a substantially airtight seal therebetween.

Abstract translation: 包括外套管组件，内插管组件和柔性密封件的骨髓抽吸组件。 外套管组件包括外手柄和限定第一通道的外套管，并且包括在第一通道的第一端和第二端之间的多个第一开口。 内部插管组件包括内部手柄和限定第二通道的内部插管，并被配置为容纳在第一通道内。 内套管包括在第二通道的第一端和第二端之间的多个第二开口。 柔性密封件安装到内手柄并定位成使得当内套管组件与外套管组件协作以在其间形成基本上气密的密封时，密封件接触外插管组件。

公开(公告)号：US20110192804A1

公开(公告)日：2011-08-11

申请号：US13089591

申请日：2011-04-19

Applicant: Matthew D. Landrigan ,  Michael D. Leach ,  Joel C. Higgins

Inventor： Matthew D. Landrigan ,  Michael D. Leach ,  Joel C. Higgins

IPC: B01D21/00 ,  B01D21/30

CPC classification number: G01N1/4077 ,  B01D17/0217 ,  B01D21/003 ,  B01D21/262 ,  B01D21/307 ,  B01D2221/10 ,  B01L3/50215 ,  B01L9/54 ,  B01L2200/026 ,  B01L2400/0409 ,  B01L2400/0478 ,  G01N33/491

Abstract: An apparatus that allows for separating and collecting a fraction of a sample. The apparatus, when used with a centrifuge, allows for the creation of at various fractions in the apparatus. A buoy system that may include a first buoy portion and a second buoy member operably interconnected may be used to form at least three fractions from a sample during a substantially single centrifugation process. Therefore, the separation of various fractions may be substantially quick and efficient. Also selected fractions from the sample can be applied to a patient, either alone or as part of a mixture.

公开(公告)号：US08728008B2

公开(公告)日：2014-05-20

申请号：US12849412

申请日：2010-08-03

Applicant: Matthew D. Landrigan ,  James M. McKale

Inventor： Matthew D. Landrigan ,  James M. McKale

IPC: A61M25/10

CPC classification number: A61B10/025 ,  A61B2010/0258

Abstract: A bone marrow aspiration assembly including an outer cannula and an inner cannula. The inner cannula is moved only radially about a longitudinal axis thereof with respect to the outer cannula to selectively align inner openings of only one of distal, intermediate, and proximal opening groups of the inner cannula with outer openings of only one of distal, intermediate, and proximal opening groups of the outer cannula to permit aspiration therethrough.

Abstract translation: 包括外套管和内插管的骨髓抽吸组件。 内套管相对于外套管的纵向轴线径向移动，以便仅选择性地将内套管的远端，中间和近侧开口组中的一个的内部开口与只有远端的，中间的， 和外套管的近端开口组以允许穿过其中。

公开(公告)号：US08567609B2

公开(公告)日：2013-10-29

申请号：US13089591

申请日：2011-04-19

Applicant: Matthew D. Landrigan ,  Michael D. Leach ,  Joel C. Higgins

Inventor： Matthew D. Landrigan ,  Michael D. Leach ,  Joel C. Higgins

IPC: B01D21/26

CPC classification number: G01N1/4077 ,  B01D17/0217 ,  B01D21/003 ,  B01D21/262 ,  B01D21/307 ,  B01D2221/10 ,  B01L3/50215 ,  B01L9/54 ,  B01L2200/026 ,  B01L2400/0409 ,  B01L2400/0478 ,  G01N33/491

Abstract: An apparatus that allows for separating and collecting a fraction of a sample. The apparatus, when used with a centrifuge, allows for the creation of at various fractions in the apparatus. A buoy system that may include a first buoy portion and a second buoy member operably interconnected may be used to form at least three fractions from a sample during a substantially single centrifugation process. Therefore, the separation of various fractions may be substantially quick and efficient. Also selected fractions from the sample can be applied to a patient, either alone or as part of a mixture.

Abstract translation: 允许分离和收集一部分样品的装置。 该设备在与离心机一起使用时允许在设备中以各种分数的形式产生。 可以使用可包括第一浮标部分和可操作地连接的第二浮标部件的浮标系统，以在基本上单个的离心过程期间从样品形成至少三个级分。 因此，各种馏分的分离可以基本上快速有效。 也可以将来自样品的选择的部分单独或作为混合物的一部分施用于患者。

公开(公告)号：US20120136277A1

公开(公告)日：2012-05-31

申请号：US13332799

申请日：2011-12-21

Applicant: Matthew D. Landrigan ,  James M. McKale

Inventor： Matthew D. Landrigan ,  James M. McKale

IPC: A61B10/02

CPC classification number: A61B10/025 ,  A61B2010/0258

Abstract: A bone marrow aspiration assembly including an outer cannula assembly, an inner cannula assembly, and a flexible seal. The outer cannula assembly includes an outer handle and an outer cannula defining a first passageway and including a plurality of first openings between a first end and a second end of the first passageway. The inner cannula assembly includes an inner handle and an inner cannula defining a second passageway and is configured to be received within the first passageway. The inner cannula includes a plurality of second openings between a first end and a second end of the second passageway. The flexible seal is mounted to the inner handle and positioned such that the seal contacts the outer cannula assembly when the inner cannula assembly is in cooperation with the outer cannula assembly to create a substantially airtight seal therebetween.

Abstract translation: 包括外套管组件，内插管组件和柔性密封件的骨髓抽吸组件。 外套管组件包括外手柄和限定第一通道的外套管，并且包括在第一通道的第一端和第二端之间的多个第一开口。 内部插管组件包括内部手柄和限定第二通道的内部插管，并被配置为容纳在第一通道内。 内套管包括在第二通道的第一端和第二端之间的多个第二开口。 柔性密封件安装到内手柄并定位成使得当内套管组件与外套管组件协作以在其间形成基本上气密的密封时，密封件接触外插管组件。