公开(公告)号：WO1996032066A1

公开(公告)日：1996-10-17

申请号：PCT/US1996005123

申请日：1996-04-12

Applicant: NEOVISION CORPORATION

Inventor： NEOVISION CORPORATION ,  SHMULEWITZ, Ascher ,  ZIRING, Edo

IPC: A61B08/14

CPC classification number: A61B8/4281 ,  A61B8/0833 ,  A61B8/0841 ,  A61B10/0233 ,  A61B17/3403 ,  A61B90/11 ,  A61B90/17 ,  A61B2090/378 ,  A61B2562/168

Abstract: Apparatus and methods are provided for positioning a biopsy needle (19) for insertion into a tissue mass by correlating, in real-time, the actual needle position prior to insertion with its probable trajectory once inserted. In a preferred embodiment, the biopsy needle (19) location is tracked electronically and projected over a previously stored or real-time image of the tissue, thus allowing a clinician to observe which features of an imaged tissue the biopsy needle (19) is likely to intersect upon insertion. Continued ultrasound scanning of a selected trajectory may be provided to assess depth of penetration of the biopsy needle (19), when inserted. The apparatus is also provided for expanding the region scanned by an ultrasound transducer (13) beyond the periphery of a compression plate.

Abstract translation: 提供了装置和方法，用于通过将插入之前的实际针位置与其插入的可能轨迹实时相关联来定位用于插入到组织块中的活检针（19）。 在优选实施例中，活检针（19）位置被电子跟踪并投影在组织的先前存储的或实时图像上，从而允许临床医生观察活检针（19）可能的成像组织的哪些特征 插入时相交。 可以提供所选轨迹的连续超声扫描，以便在插入时评估活检针（19）的穿透深度。 该装置还用于将由超声换能器（13）扫描的区域扩展到压缩板的周边之外。

公开(公告)号：WO1998002094A1

公开(公告)日：1998-01-22

申请号：PCT/US1997011434

申请日：1997-07-08

Applicant: NEOVISION CORPORATION

Inventor： NEOVISION CORPORATION ,  CROSBY, Peter, Andrew ,  SHMULEWITZ, Ascher

IPC: A61B06/04

CPC classification number: A61B8/0825 ,  A61B6/0414 ,  A61B6/4417 ,  A61B6/502 ,  A61B8/4416 ,  A61B8/483

Abstract: Apparatus and methods are provided for compressing biological tissue for use with a radiographic or sonographic imaging system that enhances imaging of the tissue near a patient's chest wall. The apparatus (10) includes a compression assembly having first (21) and second (22) compression surfaces, and structure (31) for positioning the first compression surface relative to the second compression surface, so that the first and second compression surfaces experience a lateral translation as they move towards one another. In addition, the first and second compression surfaces may be tilted slightly relative to a plane orthogonal to the patient's chest wall to enhance the traction effect, and to provide partial imaging within the patient's chest wall.

Abstract translation: 提供了用于压缩生物组织以用于增强患者胸壁附近的组织的成像的放射照相或超声成像系统的装置和方法。 装置（10）包括具有第一压缩表面（21）和第二压缩表面（22）的压缩组件和用于相对于第二压缩表面定位第一压缩表面的结构（31），使得第一和第二压缩表面经历 横向翻译，因为他们相互转移。 此外，第一和第二压缩表面可以相对于与患者胸壁垂直的平面稍微倾斜以增强牵引效果，并且在患者的胸壁内部提供部分成像。

公开(公告)号：WO1998002097A1

公开(公告)日：1998-01-22

申请号：PCT/US1997011433

申请日：1997-07-08

Applicant: NEOVISION CORPORATION

Inventor： NEOVISION CORPORATION ,  SHMULEWITZ, Ascher ,  ZIRING, Edo

IPC: A61B08/12

CPC classification number: A61B8/4281 ,  A61B8/0833 ,  A61B8/0841 ,  A61B8/4209 ,  A61B8/488 ,  A61B10/0233 ,  A61B17/3403 ,  A61B90/11 ,  A61B90/17 ,  A61B2090/378 ,  A61B2562/168 ,  Y10S128/915

Abstract: Apparatus and methods are provided for positioning a needle or cannula (54) of a biopsy device for insertion into a tissue mass by correlating, in real time, the actual needle or cannula position prior to insertion with its probable trajectory once inserted. In a preferred embodiment, a biopsy device suport block (53) is mechanically coupled to an ultrasound transducer (52) to provide alignment of the biopsy device with the ultrasound image in at least one plane. Continued ultrasound scanning of a selected trajectory may be provided to assess depth of penetration of the needle or cannula of the biopsy device when inserted.

Abstract translation: 提供了设备和方法，用于通过在插入之前实时地将实际的针或套管位置与其插入的可能轨迹相关联来定位用于插入到组织块中的活检装置的针或套管（54）。 在优选实施例中，活检装置支撑块（53）机械地耦合到超声换能器（52），以提供活检装置与至少一个平面中的超声图像的对准。 可以提供所选轨迹的持续超声波扫描，以便在插入时评估活检装置的针或插管的穿透深度。

公开(公告)号：WO1998002095A1

公开(公告)日：1998-01-22

申请号：PCT/US1997011437

申请日：1997-07-08

Applicant: NEOVISION CORPORATION

Inventor： NEOVISION CORPORATION ,  CROSBY, Peter, Andrew ,  SHMULEWITZ, Ascher

IPC: A61B06/04

CPC classification number: A61B8/4281 ,  A61B8/0825 ,  A61B8/0841 ,  A61B8/4209 ,  A61B10/0233 ,  A61B17/3403 ,  A61B90/17 ,  A61B2562/168 ,  Y10S128/915

Abstract: Apparatus (10) and methods are provided for conducting an imaging examination and/or biopsy of biological tissue that enable a patient (P) to remain in an inclined, seated orientation, so that the tissue is readily presented for examination and biopsy, while the examination and biopsy site is screened from the patient's view. Apparatus and methods are also provided for enhancing imaging of the patient's tissue near the chest wall, and for conducting image guided biopsy.

Abstract translation: 提供了用于进行生物组织的成像检查和/或活组织检查的装置（10）和方法，其使得患者（P）能够保持在倾斜的就位方向，使得组织容易地呈现用于检查和活检，而 检查和活检部位从患者的角度进行筛查。 还提供了用于增强胸壁附近患者组织成像并进行图像引导活检的装置和方法。

公开(公告)号：WO1996039939A1

公开(公告)日：1996-12-19

申请号：PCT/US1996009254

申请日：1996-06-05

Applicant: NEOVISION CORPORATION

Inventor： NEOVISION CORPORATION ,  GETZINGER, Thomas, W. ,  SHMULEWITZ, Ascher

IPC: A61B08/08

CPC classification number: G06T3/4061 ,  A61B6/12 ,  A61B6/502 ,  A61B6/5247 ,  A61B8/0825 ,  A61B8/5238 ,  A61B10/0233 ,  A61B17/3403 ,  A61B2562/168

Abstract: Apparatus and methods are provided for correlating radiologic and ultrasonic images of biological tissue (22). An X-ray image and a plurality of corresponding ultrasound images are generated while the biological tissue remains immobilized. X-ray opaque indexing points (72, 74, 76) provide lateral registration of the X-ray film (28) with the ultrasound apparatus (19). The fan-out of X-ray beams penetrating the tissue from a point X-ray source (38) is determined and used to correlate the X-ray image data to the ultrasonic image data. Apparatus and methods are also provided for determining the location of the X-ray source (38) relative to the indexing points (72, 74, 76).

Abstract translation: 提供了用于使生物组织的放射学和超声波图像相关的装置和方法（22）。 在生物组织保持固定的同时产生X射线图像和多个对应的超声图像。 X射线不透明分度点（72,74,76）提供X射线胶片（28）与超声波装置（19）的横向配准。 确定从点X射线源（38）穿透组织的X射线束的扇出，并将其用于将X射线图像数据与超声波图像数据相关联。 还提供了用于确定X射线源（38）相对于分度点（72,74,76）的位置的装置和方法。

公开(公告)号：WO1996027327A1

公开(公告)日：1996-09-12

申请号：PCT/US1996002856

申请日：1996-02-28

Applicant: NEOVISION CORPORATION

Inventor： NEOVISION CORPORATION ,  EGGERS, Philip, E. ,  SHMULEWITZ, Ascher

IPC: A61B05/05

CPC classification number: A61B18/1402 ,  A61B5/0531 ,  A61B18/1206 ,  A61B18/14 ,  A61B18/1477 ,  A61B18/1482 ,  A61B18/1485 ,  A61B18/1487 ,  A61B2018/0022 ,  A61B2018/00577 ,  A61B2018/00666 ,  A61B2018/00678 ,  A61B2018/00708 ,  A61B2018/00761 ,  A61B2018/00827 ,  A61B2018/00875 ,  A61B2018/00886 ,  A61B2018/0091 ,  A61B2018/00916 ,  A61B2018/126 ,  A61B2018/1273 ,  A61B2018/128 ,  A61B2018/1425 ,  A61B2018/162

Abstract: Apparatus and methods are provided for performing an in situ characterization of a tissue mass which may be normal, malignant, or benign, and, based on the measured characteristics of the tissue mass, therapeutically treating the tissue mass to cause necrosis of the tissue. In an illustrative preferred embodiment, the characterization of the tissue is accomplished by measuring an electrical property of the tissue, such as electrical impedance, while treatment is accomplished by supplying heat to the tissue to induce cauterization. A probe (20) includes a plurality of electrodes (51-56) to effect the characterization and treatment.

Abstract translation: 提供了设备和方法，用于对可能是正常，恶性或良性的组织块进行原位表征，并且基于组织块的测量特征，治疗性地治疗组织块以引起组织坏死。 在说明性的优选实施例中，组织的表征通过测量组织的电性质（例如电阻抗）来实现，而通过向组织供应热量以诱导烧灼来实现治疗。 探针（20）包括多个用于进行表征和处理的电极（51-56）。

公开(公告)号：WO1995011627A1

公开(公告)日：1995-05-04

申请号：PCT/US1994012118

申请日：1994-10-21

Applicant: NEOVISION CORPORATION

Inventor： NEOVISION CORPORATION ,  SHMULEWITZ, Ascher

IPC: A61B06/00

CPC classification number: A61B8/4483 ,  A61B6/4291 ,  A61B6/4417 ,  A61B6/502 ,  A61B6/5247 ,  A61B8/0825 ,  A61B8/4209 ,  A61B8/4272 ,  A61B10/0233 ,  A61B17/3403 ,  A61B90/17 ,  A61B2017/00902 ,  A61B2017/00924 ,  A61B2562/168 ,  Y10S128/915

Abstract: Apparatus (10) is provided that combines mammography equipment with an ultrasonic transducer (16) to generate ultrasonic images of the internal structure of breast tissue that are in geometric registration with a mammogram. The apparatus includes a radiolucent and sonolucent compression plate (15), and in alternative embodiments, a gantry driven ultrasound transducer (16) or a phased array ultrasonic transducer. Methods are provided for generating a mammogram and a plurality of corresponding ultrasound images without moving the breast between the mammogram exposure and the ultrasound imaging. Methods are also provided for viewing and analyzing the ultra sound images. Apparatus and methods are also provided for enhancing X-ray images obtained from conventional mammographic systems, and with reduced overall X-ray dosage to the patient.

Abstract translation: 提供了将乳房X线照相设备与超声换能器（16）组合以产生与乳房X线照相几何对准的乳房组织内部结构的超声波图像的装置（10）。 该设备包括射线可透射和声光压缩板（15），并且在替代实施例中，是龙门驱动的超声换能器（16）或相控阵列超声换能器。 提供了用于产生乳房X线照片和多个对应的超声波图像而不在乳房X线照相曝光和超声成像之间移动乳房的方法。 还提供了用于观看和分析超声图像的方法。 还提供了用于增强从常规乳房X线照相系统获得的X射线图像以及减少对患者的总X射线剂量的装置和方法。