公开(公告)号：WO2008109298A3

公开(公告)日：2008-12-24

申请号：PCT/US2008055025

申请日：2008-02-26

Applicant: NEURONEXUS TECHNOLOGIES INC ,  VETTER RIO ,  KIPKE DARYL ,  PELLINEN DAVID ,  ANDERSON DAVID ,  HETKE JAMILLE FARRAYE

Inventor： VETTER RIO ,  KIPKE DARYL ,  PELLINEN DAVID ,  ANDERSON DAVID ,  HETKE JAMILLE FARRAYE

IPC: A61N1/00

CPC classification number: A61N1/0534 ,  A61B5/04001 ,  A61N1/0539 ,  A61N1/36082

Abstract: The neural interface system of the preferred embodiments includes an electrode array having a plurality of electrode sites and a carrier that supports the electrode array. The electrode array is coupled to the carrier such that the electrode sites are arranged both circumferentially around the carrier and axially along the carrier. A group of the electrode sites may be simultaneously activated to create an activation pattern. The system of the preferred embodiment is preferably designed for deep brain stimulation, and, more specifically, for deep brain stimulation with fine electrode site positioning, selectivity, tunability, and precise activation patterning. The system of the preferred embodiments, however, may be alternatively used in any suitable environment (such as the spinal cord, peripheral nerve, muscle, or any other suitable anatomical location) and for any suitable reason.

Abstract translation: 优选实施例的神经接口系统包括具有多个电极位置的电极阵列和支撑电极阵列的载体。 电极阵列耦合到载体，使得电极位置沿着载体周向布置并且沿着载体轴向布置。 可以同时激活一组电极部位以产生激活模式。 优选实施例的系统优选地设计用于深部脑刺激，更具体地，针对具有精细电极位置定位，选择性，可调性和精确激活图案化的深部脑刺激。 然而，优选实施例的系统可以替代地在任何合适的环境（例如脊髓，周围神经，肌肉或任何其他合适的解剖学位置）中使用，并且由于任何合适的原因。

公开(公告)号：EP2683439A4

公开(公告)日：2014-08-27

申请号：EP12755209

申请日：2012-03-09

Applicant: NEURONEXUS TECHNOLOGIES INC

Inventor： SEYMOUR JOHN ,  HETKE JAMILLE ,  VETTER RIO ,  KIPKE DARYL ,  PELLINEN DAVID ,  KONG K C

IPC: A61N1/00

CPC classification number: A61N1/0534 ,  A61B1/07 ,  A61M25/0009 ,  A61M25/0023 ,  A61N1/0553 ,  A61N5/0601 ,  A61N2005/0632 ,  H05K1/028 ,  H05K1/118 ,  H05K3/10 ,  H05K2201/051 ,  Y10T29/4913 ,  Y10T29/49147 ,  Y10T29/49155

Abstract: The neural interface system of one embodiment includes a cylindrical shaft, a lateral extension longitudinally coupled to at least a portion of the shaft and having a thickness less than a diameter of the shaft, and an electrode array arranged on the lateral extension and radially offset from the shaft, including electrode sites that electrically interface with their surroundings. The method of one embodiment for making the neural interface system includes forming a planar polymer substrate with at least one metallization layer, patterning on at least one metallization layer an electrode array on a first end of the substrate, patterning conductive traces on at least one metallization layer, rolling a portion of the substrate toward the first end of the substrate, and securing the rolled substrate into a shaft having the first end of the substrate laterally extending from the shaft and the electrode array radially offset from the shaft.

Abstract translation: 一个实施例的神经接口系统包括圆柱形轴，纵向耦合到轴的至少一部分并且具有小于轴的直径的厚度的横向延伸部以及布置在横向延伸部上且径向偏移的电极阵列 轴，包括与其周围环境电接触的电极位置。 用于制造神经界面系统的一个实施例的方法包括形成具有至少一个金属化层的平面聚合物衬底，在至少一个金属化层上图案化在衬底的第一端上的电极阵列，在至少一个金属化层上图案化导电迹线 将基板的一部分朝向基板的第一端滚动，并且将卷绕的基板固定到轴中，该轴具有从轴向轴向延伸的基板的第一端部，并且电极阵列从轴向径向偏移。