公开(公告)号：WO1994023643A1

公开(公告)日：1994-10-27

申请号：PCT/US1993003427

申请日：1993-04-12

Applicant: NONINVASIVE MEDICAL TECHNOLOGY CORPORATION

Inventor： NONINVASIVE MEDICAL TECHNOLOGY CORPORATION ,  STEUER, Robert, R. ,  HARRIS, David, B.

IPC: A61B05/00

CPC classification number: G01N21/3151 ,  A61B5/14535 ,  A61B5/14546 ,  A61B5/14551 ,  A61B5/14552 ,  A61B5/6826 ,  A61B5/6838 ,  A61B5/6843 ,  G01N2021/3144 ,  G01N2021/3148 ,  G01N2021/3181 ,  G01N2201/0625 ,  G01N2201/0691

Abstract: A system for determining the hematocrit transcutaneously and noninvasively. Disclosed are a finger clip assembly (6) and an earlobe clip assembly (10), each including at least a pair of emitters (1, 2) and a photodiode (3) in appropriate alignment to enable operation in either a transmittion mode or a reflectance mode. At least two, and preferably three, predetermined wavelengths of light are passed onto or through body tissues such as the finger (7), earlobe (11), or scalp, etc. and the extinction of each wavelength is detected. Mathematical manipulation of the detected values compensates for the effects of body tissue and fluid and determines the hematocrit value. If a fourth wavelength of light is used which is extinguished substantially differently by oxyhemoglobin and reduced hemoglobin and which is not substantially extinguished by plasma, then the blood oxygen saturation value, is determinable independently of the hematocrit value. It is also within the scope of the present invention to detect and analyze multiple wavelengths using a logarithmic DC analysis technique. In this embodiment, a pulse wave is not required. Hence, this embodiment may be utilized in states of low blood pressure or low blood flow.

Abstract translation: 用于经皮和非侵入性测定血细胞比容的系统。 公开了一种手指夹组件（6）和耳垂夹子组件（10），每个夹片组件（10）均包括至少一对发射器（1,2）和光电二极管（3），以适当对准，以使得能够以透射模式或 反射模式。 至少两个，优选三个预定波长的光通过身体组织，例如手指（7），耳垂（11）或头皮等，并且检测每个波长的消光。 检测值的数学操作可补偿身体组织和液体的影响，并确定血细胞比容值。 如果使用第四波长的光，其通过氧合血红蛋白和血红蛋白降低而基本上不同，并且其基本上不被血浆消除，则血氧饱和度值可以独立于血细胞比容值来确定。 使用对数DC分析技术来检测和分析多个波长也在本发明的范围内。 在本实施例中，不需要脉波。 因此，该实施例可以用于低血压或低血流量的状态。

公开(公告)号：EP0693900A1

公开(公告)日：1996-01-31

申请号：EP93910585.0

申请日：1993-04-12

Applicant: Noninvasive Medical Technology Corporation

Inventor： STEUER, Robert, R. ,  HARRIS, David, B.

IPC: A61B5 ,  G01N21

CPC classification number: G01N21/3151 ,  A61B5/14535 ,  A61B5/14546 ,  A61B5/14551 ,  A61B5/14552 ,  A61B5/6826 ,  A61B5/6838 ,  A61B5/6843 ,  G01N2021/3144 ,  G01N2021/3148 ,  G01N2021/3181 ,  G01N2201/0625 ,  G01N2201/0691

Abstract: A system for determining the hematocrit transcutaneously and noninvasively. Disclosed are a finger clip assembly (6) and an earlobe clip assembly (10), each including at least a pair of emitters (1, 2) and a photodiode (3) in appropriate alignment to enable operation in either a transmittion mode or a reflectance mode. At least two, and preferably three, predetermined wavelengths of light are passed onto or through body tissues such as the finger (7), earlobe (11), or scalp, etc. and the extinction of each wavelength is detected. Mathematical manipulation of the detected values compensates for the effects of body tissue and fluid and determines the hematocrit value. If a fourth wavelength of light is used which is extinguished substantially differently by oxyhemoglobin and reduced hemoglobin and which is not substantially extinguished by plasma, then the blood oxygen saturation value, is determinable independently of the hematocrit value. It is also within the scope of the present invention to detect and analyze multiple wavelengths using a logarithmic DC analysis technique. In this embodiment, a pulse wave is not required. Hence, this embodiment may be utilized in states of low blood pressure or low blood flow.