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    Hla-binding peptide, dna fragment encoding the same, and recombinant vector
    1.
    发明专利
    Hla-binding peptide, dna fragment encoding the same, and recombinant vector 有权
    HLA-BINDING PEPTIDE，编码其的DNA片段和重组载体

    公开(公告)号：JP2012115274A

    公开(公告)日：2012-06-21

    申请号：JP2012011305

    申请日：2012-01-23

    Applicant: Kochi Univ ,  Nec Corp ,  国立大学法人高知大学 ,  日本電気株式会社

    Inventor： MIYAGAWA TOMOYA ,  UKO KEIKO

    IPC: C12N15/09 ,  C07K7/06 ,  C07K14/47

    CPC classification number: C07K14/70539 ,  C07K16/2833

    Abstract: PROBLEM TO BE SOLVED: To provide an HLA-binding peptide excellent in bondability to an HLA-A type molecule.SOLUTION: The HLA-binding peptide binding to an HLA-A type molecule is an HLA binding peptide which contains a specific amino acid sequence, including not less than 8 and not more than 11 amino acid residues and whose bondability to a human HLA-A molecule is predicted by means of a prediction program employing an active learning experiment method shown in Fig.1. The DNA fragments include a DNA sequence encoding the HLA binding peptide, and a recombinant vector includes the DNA sequence.

    Abstract translation: 待解决的问题：提供对HLA-A型分子的结合性优异的HLA结合肽。 结合HLA-A型分子的HLA结合肽是HLA结合肽，其含有特定氨基酸序列，包括不少于8个且不超过11​​个氨基酸残基，并且其与人的结合能力 通过使用图1所示的主动学习实验方法的预测程序来预测HLA-A分子。 DNA片段包括编码HLA结合肽的DNA序列，重组载体包括DNA序列。 版权所有（C）2012，JPO＆INPIT

    Array display method/device/program/recording medium, and homology retrieval method/device/ program/recording medium
    2.
    发明专利
    Array display method/device/program/recording medium, and homology retrieval method/device/ program/recording medium 审中-公开

    公开(公告)号：JP2004192257A

    公开(公告)日：2004-07-08

    申请号：JP2002358407

    申请日：2002-12-10

    Applicant: Nec Corp ,  日本電気株式会社

    Inventor： MIYAGAWA TOMOYA ,  NAKAZATO TAKERU ,  ASOGAWA MINORU ,  KENMOCHI AKIHISA

    IPC: C12N15/09 ,  C12Q1/68 ,  G06F3/14 ,  G06F7/00 ,  G06F17/30 ,  G06F19/22 ,  G06F19/26

    CPC classification number: G06F19/26 ,  G06F19/22

    Abstract: PROBLEM TO BE SOLVED: To provide an array display method and a homology retrieval method capable of simplifying access to information associated with inter-array variation sites or common sites, and result-displaying a plurality of retrieved arrays as they are.
    SOLUTION: This array display method is provided to add visual characteristics corresponding to variability and/or commonality in a plurality of similar base arrays or amino acid arrays. The visual characteristics are added to variation sites and/or common sites, and added according to the level of variability and/or commonality and the frequency of the variability in the variation sites. Furthermore, the visual characteristics for converting the base arrays into amino acid arrays are added based on the amino acid information including amino acid names and characteristics corresponding to the codon of the variation sites. A link to information associated with the plurality of similar base arrays or amino acid arrays is set. This homology retrieval method is provided to display a retrieval result by using the array display method.
    COPYRIGHT: (C)2004,JPO&NCIPI

    Hla-binding peptide, dna fragment encoding the same and recombinant vector
    4.
    发明专利
    Hla-binding peptide, dna fragment encoding the same and recombinant vector 审中-公开
    HLA-BINDING PEPTIDE，DNA片段编码其和重组载体

    公开(公告)号：JP2011120598A

    公开(公告)日：2011-06-23

    申请号：JP2011012175

    申请日：2011-01-24

    Applicant: Kochi Univ ,  Nec Corp ,  国立大学法人高知大学 ,  日本電気株式会社

    Inventor： MIYAGAWA TOMOYA ,  UKO KEIKO

    IPC: C12N15/09 ,  C07K7/06 ,  C07K14/18 ,  C12N15/11

    CPC classification number: C07K14/47 ,  C07K14/005 ,  C12N2770/24222

    Abstract: PROBLEM TO BE SOLVED: To provide an HLA-binding peptide excellent in binding to an HLA-A type molecule.
    SOLUTION: The HLA-binding peptide, which binds to an HLA-A type molecule, contains a specific amino acid sequences and consists of 8 or more but not more than 11 amino acid residues. Any of the amino acid sequences have been predicted, by a prediction program by the use of the active learning technology shown in Fig. 1, to have the property to bind to a human HLA-A24 and/or a human HLA-A2 molecule.
    COPYRIGHT: (C)2011,JPO&INPIT

    Abstract translation: 待解决的问题：提供与HLA-A型分子结合优异的HLA结合肽。 解决方案：结合HLA-A型分子的HLA结合肽含有特定的氨基酸序列，由8个或更多但不超过11​​个氨基酸残基组成。 通过使用图1所示的主动学习技术的预测程序已经预测了任何氨基酸序列。 1，具有与人HLA-A24和/或人类HLA-A2分子结合的性质。 版权所有（C）2011，JPO＆INPIT

    Hla-binding peptide, dna fragment coding for the same and recombinant vector
    6.
    发明专利
    Hla-binding peptide, dna fragment coding for the same and recombinant vector 审中-公开
    HLA-BINDING PEPTIDE，其DNA片段编码及其重组载体

    公开(公告)号：JP2006230269A

    公开(公告)日：2006-09-07

    申请号：JP2005048660

    申请日：2005-02-24

    Applicant: Kochi Univ ,  Nec Corp ,  国立大学法人高知大学 ,  日本電気株式会社

    Inventor： MIYAGAWA TOMOYA ,  UKO KEIKO

    IPC: C12N15/09 ,  C07K14/82

    Abstract: PROBLEM TO BE SOLVED: To provide an HLA (human leukocyte antigen)-binding peptide excellent in bindability to HLA-A type molecules. SOLUTION: The HLA-binding peptide binds to the HLA-A type molecules, contains one or more species amino acid sequences selected from a group having specific amino acid sequences and comprises 8-11 amino acid residues. Each of the amino acid sequences is predicted for its bindability to the human HLA-A type molecules by making use of a prediction program using an active learning method. COPYRIGHT: (C)2006,JPO&NCIPI

    Abstract translation: 待解决的问题：提供对HLA-A型分子的结合性优异的HLA（人白细胞抗原）结合肽。 解决方案：HLA结合肽结合HLA-A型分子，含有选自具有特定氨基酸序列的一个或多个种类的氨基酸序列并且包含8-11个氨基酸残基。 通过使用使用主动学习方法的预测程序来预测每个氨基酸序列对于HLA-A型分子的可结合性。 版权所有（C）2006，JPO＆NCIPI

    Hla-binding peptide, dna fragment encoding the same and recombinant vector
    7.
    发明专利
    Hla-binding peptide, dna fragment encoding the same and recombinant vector 有权
    HLA-BINDING PEPTIDE，DNA片段编码其和重组载体

    公开(公告)号：JP2012229225A

    公开(公告)日：2012-11-22

    申请号：JP2012135797

    申请日：2012-06-15

    Applicant: Nec Corp ,  日本電気株式会社 ,  Kochi Univ ,  国立大学法人高知大学

    Inventor： MIYAGAWA TOMOYA ,  UKO KEIKO

    IPC: C07K16/28 ,  A61K39/145 ,  C12N15/09

    CPC classification number: C07K14/005 ,  A61K38/00 ,  A61K38/08 ,  A61K39/00 ,  A61K39/12 ,  A61K39/145 ,  C07K7/06 ,  C12N2760/16022 ,  C12N2760/16034

    Abstract: PROBLEM TO BE SOLVED: To provide an HLA-binding peptide and a precursor thereof, to provide a DNA fragment encoding the same, and to provide a recombinant vector.SOLUTION: There is provided an HLA-binding peptide binding to an HLA-A type molecule, which includes one or more amino acid sequence selected from the group consisting of specific sequences, and comprises ≥8 and ≤11 amino acid residues. Additionally, these amino acid sequences are predicted to bind to a human HLA-A molecule by using a prediction program utilizing an active learning system.

    Abstract translation: 待解决的问题：提供HLA结合肽及其前体，以提供编码该HLA的结合肽及其前体，并提供重组载体。 提供了结合HLA-A型分子的HLA结合肽，其包括一个或多个选自特异性序列的氨基酸序列，并且包含≥8个和≤11个氨基酸残基。 另外，通过使用利用主动学习系统的预测程序，预测这些氨基酸序列与人HLA-A分子结合。 版权所有（C）2013，JPO＆INPIT

    Biological information retrieval system and its method
    8.
    发明专利
    Biological information retrieval system and its method 审中-公开

    公开(公告)号：JP2004318321A

    公开(公告)日：2004-11-11

    申请号：JP2003109054

    申请日：2003-04-14

    Applicant: Nec Corp ,  日本電気株式会社

    Inventor： NAKAZATO TAKERU ,  MIYAGAWA TOMOYA ,  KENMOCHI AKIHISA ,  ASOGAWA MINORU

    IPC: G06F17/30

    CPC classification number: G06F19/28

    Abstract: PROBLEM TO BE SOLVED: To provide a biological information retrieval system and method for solving a problem in retrieving a biological database that it is impossible to retrieve a gene or protein with anything other than its name.
    SOLUTION: A user input accepting part 11 which has received an inquiry from a user to a biological information database generates a user query 111, and a query generating part 12 generates a biological information database query 121, and a biological information database retrieval part 13 actually retrieves a biological information database 999, and outputs a biological information database retrieval result 133. A retrieval result analysis part 14 analyzes the retrieval result, and outputs an analysis result 142, and an output control part 15 receives the analysis result, and successively outputs it, and generates a re-retrieval query 151 for non-retrieval, and transmits it to the query generating part 12. An output information designating and holding part 16 preliminarily holds conditions associated with the extraction and output of the retrieval result.
    COPYRIGHT: (C)2005,JPO&NCIPI

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