公开(公告)号：US20180273529A1

公开(公告)日：2018-09-27

申请号：US15763389

申请日：2016-09-12

Applicant: ONCOTHERAPY SCIENCE, INC.

Inventor： YO MATSUO ,  Shoji Hisada ,  Yusuke Nakamura ,  Anjan Chakrabarti ,  Manish Rawat ,  Sanjay Rai ,  Arvapalli Venkata Satyanarayana ,  Zhiyong Duan ,  Arindam Talukdar ,  Srinivas Ravula ,  Helene Decornez

IPC: C07D471/04 ,  C07D487/04 ,  C07F9/6561

CPC classification number: C07D471/04 ,  A61P35/00 ,  C07D451/00 ,  C07D487/04 ,  C07D519/00 ,  C07F9/6561

Abstract: The present invention directs to a compound represented by formula (I).

公开(公告)号：US09453025B2

公开(公告)日：2016-09-27

申请号：US14565047

申请日：2014-12-09

Applicant: ONCOTHERAPY SCIENCE, INC.

Inventor： Yusuke Nakamura ,  Yo Matsuo ,  Shoji Hisada ,  Feryan Ahmed ,  Raymond Huntley ,  Zohreh Sajjadi-Hashemi ,  David M. Jenkins ,  Robert B. Kargbo ,  Wenge Cui ,  Polivina Jolicia F. Gauuan ,  Joel R. Walker ,  Helene Decornez ,  Mahender Gurram

IPC: A61K31/44 ,  A61K31/38 ,  C07D455/04 ,  C07D333/50 ,  C07D495/04 ,  C07D221/06 ,  C07D487/04 ,  C07D513/04 ,  C07D221/16 ,  C07D401/10 ,  C07D213/64 ,  C07D401/04 ,  C07D519/00

CPC classification number: C07D495/04 ,  C07D213/64 ,  C07D221/06 ,  C07D221/16 ,  C07D401/04 ,  C07D401/10 ,  C07D487/04 ,  C07D513/04 ,  C07D519/00

Abstract: Tricyclic compounds are provided. These compounds are PBK inhibitors, and are useful for the treatment of PBK related diseases, including cancer.

公开(公告)号：US10508109B2

公开(公告)日：2019-12-17

申请号：US15763389

申请日：2016-09-12

Applicant: ONCOTHERAPY SCIENCE, INC.

Inventor： Yo Matsuo ,  Shoji Hisada ,  Yusuke Nakamura ,  Anjan Chakrabarti ,  Manish Rawat ,  Sanjay Rai ,  Arvapalli Venkata Satyanarayana ,  Zhiyong Duan ,  Arindam Talukdar ,  Srinivas Ravula ,  Helene Decornez

IPC: C07D471/04 ,  C07D451/00 ,  C07D487/04 ,  C07D519/00 ,  C07F9/6561 ,  A61P35/00

Abstract: The present invention directs to a compound represented by formula (I).