公开(公告)号：CA2691510A1

公开(公告)日：2008-12-31

申请号：CA2691510

申请日：2008-06-26

Applicant: ONCOTHERAPY SCIENCE INC

Inventor： TOGASHI AKIRA ,  TOBITA RYUTARO ,  ISHIZAKI YUKA ,  KONUMA AKIKO

IPC: C12N15/00 ,  A61K31/7105 ,  A61K48/00 ,  A61P35/00

Abstract: The invention features a method for treating cancer by administering a do uble-stranded nucleic acid molecule against a CX gene selected from the grou p consisting of C14orf78, MYBL2, UBE2S and UBE2T. The invention also feature s products, including the double-stranded nucleic acid molecules and vectors encoding them, as well as compositions comprising the molecules or vectors, useful in the provided methods. The methods of the invention are suited for the treatment of cancers including lung cancer, breast cancer, bladder canc er, esophagus cancer, prostate cancer, cholangiocellular carcinoma and testi cular seminoma.

公开(公告)号：BRPI0812932A2

公开(公告)日：2014-12-09

申请号：BRPI0812932

申请日：2008-06-26

Applicant: ONCOTHERAPY SCIENCE INC

Inventor： TOGASHI AKIRA ,  TOBITA RYUTARO ,  ISHIZAKI YUKA ,  KONUMA AKIKO

IPC: C12N15/00 ,  A61K31/7105 ,  A61K48/00 ,  A61P35/00

Abstract: The invention features a method for treating cancer by administering a double-stranded nucleic acid molecule against a CX gene selected from the group consisting of C14orf78, MYBL2, UBE2S and UBE2T. The invention also features products, including the double-stranded nucleic acid molecules and vectors encoding them, as well as compositions comprising the molecules or vectors, useful in the provided methods. The methods of the invention are suited for the treatment of cancers including lung cancer, breast cancer, bladder cancer, esophagus cancer, prostate cancer, cholangiocellular carcinoma and testicular seminoma.

公开(公告)号：EP2176406A4

公开(公告)日：2011-10-19

申请号：EP08776735

申请日：2008-06-26

Applicant: ONCOTHERAPY SCIENCE INC

Inventor： TOGASHI AKIRA ,  TOBITA RYUTARO ,  ISHIZAKI YUKA ,  KONUMA AKIKO

IPC: C12N15/11 ,  A61K31/7105 ,  A61P35/00

CPC classification number: C12N15/113 ,  C12N2310/14