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    2.
    发明专利
    未知

    公开(公告)号：AT302581T

    公开(公告)日：2005-09-15

    申请号：AT98945345

    申请日：1998-09-22

    Applicant: OREAL

    Inventor： DE LA METTRIE ROLAND ,  COTTERET JEAN ,  DE LABBEY ARNAUD ,  MAUBRU MIREILLE

    IPC: A61K8/00 ,  A61K8/31 ,  A61K8/33 ,  A61K8/36 ,  A61K8/37 ,  A61K8/41 ,  A61K8/44 ,  A61K8/46 ,  A61K8/49 ,  A61K8/60 ,  A61K8/64 ,  A61K8/66 ,  A61K8/73 ,  A61K8/99 ,  A61Q5/00 ,  A61Q5/04 ,  A61Q5/08 ,  A61Q5/10 ,  C09B67/22 ,  A61K7/06 ,  A61K7/50

    Abstract: Cosmetic and/or dermatological composition for treating keratinic fibres comprises a carrier, at least one 2-electron oxidoreductase enzyme, at least one substrate for the enzyme, and at least one anionic surfactant selected from acyl isethionates, acyl taurates, sulphosuccinates, acyl sarcosinates, acyl glutamates, alkoxylated carboxylic acids and their salts, sulphated fatty glucamides, alkyl galactoside uronates, and anionic alkyl polyglucoside derivatives. Preferably the enzyme is an animal, microbial or recombinant uricase and is present in an amount of 0.01-20 (preferably 0.1-5) wt.%. The substrate is selected from uric acid and its salts and is present in an amount of 0.01-20 (preferably 0.1-5) wt.%. The acyl isethionates and taurates are of formula RCH2CH2SO3M; R = R1COO or R1CONR2; R1 = an 8-30C aliphatic group; R2 = H or 1-4C alkyl; and M = H, NH4, Na, K or organic ammonium. The sulphosuccinates are of formula R1OOC-CH(SO3M)-CH2COOM. The acyl sarcosinates and glutamates are of formula R2CO-NR3-CHR4-COOM; R3 = Me; and R4 = H or R3 = H; and R4 = CH2CH2COOM. The alkoxylated carboxylic acids have 2-50 ethylene oxide groups. The alkoxylated carboxylic acids or salts are of formula R5(OC2H4)nOCH2COOA; R5 = 6-20C alkyl or (6-20C alkyl)phenyl; n = 3-10; and A = H, NH4, Na, K, Li, Mg, monoethanolammonium or triethanolammonium.

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