公开(公告)号：EP3209497A4

公开(公告)日：2018-06-13

申请号：EP15851778

申请日：2015-10-26

Applicant: ORTHOBOND INC

Inventor： CLEVENGER RANDY ,  KIM SE-HO

IPC: C08J7/16 ,  C08F230/02 ,  C08F292/00 ,  C09D5/14

CPC classification number: C08F292/00 ,  C08F230/02 ,  C08F2438/01 ,  C08J7/16 ,  C09D5/14

Abstract: Disclosed herein is a composition comprising a substrate with functionalized surface covalently bound to an anti-infective agent, such as a quaternary phosphonium compound with anti-bacterial activity against a broad range of bacteria, methods of synthesizing an anti-infective composition, and its resultant antimicrobial performance.

公开(公告)号：EP3322365A1

公开(公告)日：2018-05-23

申请号：EP16800608

申请日：2016-05-23

Applicant: ORTHOBOND INC

Inventor： CLEVENGER RANDY ,  KIM SE-HO ,  KATZ JORDAN ,  CAICEDO-CARVAJAL CARLOS

IPC: A61B17/88 ,  B32B27/12

CPC classification number: A61L27/54 ,  A61L27/18 ,  A61L2300/208 ,  A61L2300/404 ,  A61L2430/04 ,  C08F220/34 ,  C08F2438/01 ,  C08L83/04

Abstract: Disclosed are novel compositions and methods for making a polymer substrate and a ligand that includes a proximal portion with a photoactive compound bound to the polymer substrate, a terminal portion with an anti-infective/anti-microbial compound, and a reactive portion attaching the proximal portion and the terminal portion.