公开(公告)号：WO2009142679A3

公开(公告)日：2010-01-14

申请号：PCT/US2009001954

申请日：2009-03-26

Applicant: ORTHOLOGIC CORP ,  STEER RANDOLPH C ,  SHELLER MICHAEL R ,  WAGSTAFF JOHN D

Inventor： STEER RANDOLPH C ,  SHELLER MICHAEL R ,  WAGSTAFF JOHN D

IPC: A61K38/48 ,  A61K38/10 ,  A61P9/10

CPC classification number: A61K38/4833

Abstract: The present invention includes methods of treating acute myocardial infarction in a subject, comprising administering to the subject a therapeutically effective amount of a non-proteolytically activated thrombin receptor agonist.

Abstract translation: 本发明包括在受试者中治疗急性心肌梗死的方法，其包括向受试者施用治疗有效量的非蛋白水解活化的凝血酶受体激动剂。

公开(公告)号：WO2009120300A3

公开(公告)日：2009-11-26

申请号：PCT/US2009001813

申请日：2009-03-24

Applicant: ORTHOLOGIC CORP ,  CARNEY DARRELL H ,  STEER RANDOLPH C

Inventor： CARNEY DARRELL H ,  STEER RANDOLPH C

IPC: A61K38/48 ,  A61P17/00 ,  A61P25/16 ,  A61P25/28 ,  A61P27/06

CPC classification number: A61K38/4833

Abstract: Agonists of a non-proteolytically activated receptor can be used in methods for treating a disease or disorder in a subject. The methods comprise administering to the subject a therapeutically effective amount of an agonist, wherein the disease or disorder is scleroderma, macular degeneration, diabetic retinopathy, Huntington's disease, Parkinson's disease, closed head trauma, glaucoma, optic neuritis or allograft vasculopathy.

Abstract translation: 非蛋白水解活化受体的激动剂可用于治疗受试者的疾病或病症的方法。 所述方法包括向受试者施用治疗有效量的激动剂，其中所述疾病或病症是硬皮病，黄斑变性，糖尿病性视网膜病变，亨廷顿舞蹈病，帕金森病，闭合性头部创伤，青光眼，视神经炎或同种异体移植血管病变。

公开(公告)号：CA2722618A1

公开(公告)日：2009-10-01

申请号：CA2722618

申请日：2009-03-24

Applicant: ORTHOLOGIC CORP

Inventor： CARNEY DARRELL H ,  STEER RANDOLPH C

IPC: A61K38/48 ,  A61P17/00 ,  A61P25/16 ,  A61P25/28 ,  A61P27/02 ,  A61P27/06

Abstract: Agonists of a non-proteolytically activated receptor can be used in methods for treating a disease or disorder in a subject. The methods comprise administering to the subject a therapeutically effective amount of an agonist, wherein the disease or disorder is scleroderma, macular degeneration, diabetic retinopathy, Huntington's disease, Parkinson's disease, closed head trauma, glaucoma, optic neuritis or allograft vasculopathy.

公开(公告)号：CA2719940A1

公开(公告)日：2009-11-26

申请号：CA2719940

申请日：2009-03-26

Applicant: ORTHOLOGIC CORP

Inventor： STEER RANDOLPH C ,  SHELLER MICHAEL R ,  WAGSTAFF JOHN D

IPC: A61K38/48 ,  A61K38/10 ,  A61P9/10

Abstract: The present invention includes methods of treating acute myocardial infarction in a subject, comprising administer-ing to the subject a therapeutically effective amount of a non-proteolytically activated thrombin receptor agonist.