公开(公告)号：US10765709B2

公开(公告)日：2020-09-08

申请号：US16308439

申请日：2017-06-13

Applicant: OXTHERA INTELLECTUAL PROPERTY AB

Inventor： Elisabeth Lindner ,  Maria Åkerman ,  Anna Sjögren ,  Orla McCallion

IPC: A61K35/74 ,  A61P1/00 ,  A61K9/48

Abstract: The present disclosure is related to pharmaceutical compositions and methods for treating and/or preventing oxalate-related disorders. More particularly, the present disclosure pertains to compositions comprising an oxalate-degrading bacteria Oxalobacter formigenes particularly suitable for the treatment and/or prevention of late stage hyperoxaluria characterized by high plasma-oxalate levels and a progressing decrease in kidney function.